1,4-dioxane

1,4-dioxane is a colorless organic solvent with the molecular formula C4H8O2 and CAS number 123-91-1. It belongs to the ether family and has a cyclic structure containing two oxygen atoms. With a molecular weight of 88.11 g/mol, it is classified as a flammable liquid and potential carcinogen. This versatile chemical compound is widely used in industrial applications due to its excellent solvent properties and miscibility with both water and organic solvents.

1,4-dioxane is a clear, colorless liquid at room temperature with a faint ethereal odor. It has excellent solubility characteristics, being completely miscible with water and most organic solvents including alcohols, ethers, and aromatic hydrocarbons. The compound has a relatively low viscosity and moderate volatility. Its cyclic ether structure gives it unique chemical stability under normal conditions, making it an effective aprotic solvent for various chemical processes and analytical applications.

1,4-dioxane is primarily used as a versatile industrial solvent in chemical synthesis, particularly in pharmaceutical and polymer manufacturing. It serves as a reaction medium for organometallic chemistry and is commonly used in laboratory applications for extraction and purification processes. The compound is also utilized in the production of adhesives, coatings, and cleaning agents. Its ability to dissolve both polar and nonpolar substances makes it valuable in analytical chemistry and as a stabilizer in certain formulations.

1,4-dioxane must be handled with extreme caution due to its carcinogenic properties and flammability. Always wear appropriate personal protective equipment including nitrile gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid all sources of ignition as it forms flammable vapors. Work in a fume hood to prevent inhalation exposure and ensure proper grounding to prevent static electricity buildup. Never eat, drink, or smoke while handling this substance, and wash hands thoroughly after use.

1,4-dioxane should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers in secondary containment and away from incompatible materials such as strong oxidizing agents. Store below 25°C and protect from light to prevent degradation. The storage area should be equipped with appropriate fire suppression systems and spill containment measures. Regular inspection of containers is essential as the compound can form explosive peroxides over time.

In case of skin contact with 1,4-dioxane, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. In all cases of exposure, contact emergency medical services promptly due to the carcinogenic nature of this substance.

1,4-dioxane must be disposed of as hazardous waste through licensed waste management companies in accordance with local and EU regulations. Never discharge into drains, waterways, or soil due to its environmental persistence and toxicity. Collect waste in appropriate containers, properly labeled with hazard information. Small laboratory quantities may require special incineration at high temperatures. Contact your local environmental authority for specific disposal requirements, as 1,4-dioxane is subject to strict waste management protocols due to its carcinogenic classification.

1,4-dioxane is classified under ADR transport regulations as Class 3 (flammable liquids), Packing Group II, indicating moderate danger level. It must be transported in approved packaging with proper hazard labels including GHS02, GHS08, and GHS07 pictograms. Transport documents must include the correct shipping name and UN identification number. Vehicles must be equipped with appropriate fire extinguishing equipment and drivers require ADR certification. Ensure proper ventilation during transport and avoid exposure to heat sources or mechanical shock.

1,4-dioxane is subject to extensive EU regulations including REACH registration requirements and CLP classification as Carcinogen 1B. It requires safety data sheets and proper hazard labeling with 'Danger' signal word. Workplace exposure limits apply under occupational health regulations. Some EU member states have additional restrictions on its use and sale. Companies handling this substance must implement risk management measures and may require special permits. Regular monitoring of workplace exposure levels is mandatory due to its carcinogenic classification.

1,4-dioxane is available through OYSI, a trusted European distributor of technical chemicals serving industrial and laboratory customers across Europe. OYSI provides this regulated substance with full compliance documentation including safety data sheets and certificates of analysis. As a specialized chemical distributor, OYSI ensures proper packaging, labeling, and transport arrangements in accordance with ADR and CLP regulations. Contact OYSI directly to discuss your specific requirements, quantities, and delivery options for 1,4-dioxane procurement.