1-methyl-2-nitrobenzene

1-methyl-2-nitrobenzene is an aromatic nitro compound with the molecular formula C7H7NO2 and CAS number 88-72-2. This organic chemical features a benzene ring substituted with both a methyl group and a nitro group in ortho positions. With a molecular weight of 137.14 g/mol, it belongs to the nitrotoluene family and is classified as a hazardous substance due to its carcinogenic, mutagenic, and reproductive toxicity properties.

1-methyl-2-nitrobenzene is typically a yellow to orange liquid at room temperature with a characteristic aromatic odor. The compound has limited solubility in water but is soluble in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. Its density is higher than water, and it exhibits typical properties of nitroaromatic compounds including light sensitivity and potential for decomposition under extreme conditions.

1-methyl-2-nitrobenzene serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of dyes, pigments, and other aromatic compounds through reduction or substitution reactions. The compound also finds applications in chemical research as a starting material for synthesizing various derivatives and in the manufacture of specialty chemicals where its unique substitution pattern is required.

1-methyl-2-nitrobenzene requires strict safety measures due to its carcinogenic and mutagenic properties. Personal protective equipment must include chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or fume hoods to prevent inhalation. Avoid skin contact and ingestion completely. Use appropriate engineering controls and ensure all personnel are trained in handling procedures for toxic substances.

1-methyl-2-nitrobenzene must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep away from strong oxidizing agents, reducing agents, and incompatible materials. Storage areas should be equipped with appropriate containment systems and emergency equipment. Containers should be properly labeled and stored in secondary containment to prevent environmental contamination in case of leakage.

Immediate action is required upon contact with 1-methyl-2-nitrobenzene due to its toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure incident.

1-methyl-2-nitrobenzene disposal must comply with local and international hazardous waste regulations due to its toxic properties. The substance should be collected in appropriate containers and disposed of through licensed hazardous waste disposal facilities. Incineration at high temperatures in specialized facilities is typically required. Never dispose of this chemical through regular waste streams, sewers, or soil. Consult local environmental authorities for specific disposal requirements.

1-methyl-2-nitrobenzene is classified as ADR Class 6.1 (toxic substances), Packing Group II, requiring specific transport regulations. Packages must bear appropriate hazard labels and be constructed to withstand transport conditions. Vehicles must carry emergency equipment and drivers need ADR certification. Transport documents must include proper shipping names, hazard classes, and emergency response information. Segregation requirements must be observed to prevent incompatible cargo mixing.

1-methyl-2-nitrobenzene is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. Its classification as Carcinogenic 1B, Mutagenic 1B, and Reproductive toxicant 2 triggers strict handling, labeling, and reporting requirements. Companies must maintain safety data sheets, implement risk management measures, and comply with occupational exposure limits. Import, use, and disposal are regulated under various environmental and health protection laws.

1-methyl-2-nitrobenzene is available through OYSI, a specialized European distributor of chemical products. As a professional chemical supplier, OYSI ensures compliance with all relevant regulations and provides proper documentation including safety data sheets and certificates of analysis. Due to the hazardous nature of this substance, purchases are typically restricted to qualified industrial users with appropriate handling capabilities and regulatory compliance.