Benzene-1,3-diol
C6H6O2
benzene-1,3-diol
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Identification
- CAS Number
- 108-46-3
- EC Number
- 203-585-2
- UN Number
- 2876
- Index Number
- 604-010-00-1
- PubChem CID
- 5054
Physical-chemical properties
- Molecular Formula
- C6H6O2
- Molar Mass
- 110.11 g/mol
- IUPAC Name
- benzene-1,3-diol
Chemical Identifiers
- InChI
- InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
- InChI Key
- GHMLBKRAJCXXBS-UHFFFAOYSA-N
Overview
Benzene-1,3-diol (CAS 108-46-3) is an aromatic dihydroxy compound with strong reducing properties and significant industrial applications. This organic compound, also known by its IUPAC name benzene-1,3-diol, represents a fundamental building block in organic chemistry with the molecular formula C6H6O2 and a molecular weight of 110.11 g/mol. The substance features two hydroxyl groups positioned at the 1 and 3 positions on a benzene ring, creating a meta-dihydroxybenzene structure that exhibits distinctive chemical reactivity patterns. Its European Classification number 203-585-2 reflects its established status in industrial applications across multiple sectors. The compound presents notable safety considerations, classified under multiple hazard categories including Acute Toxicity Category 4, Specific Target Organ Toxicity Single Exposure Category 1, and various irritation and sensitization properties. The Danger signal word and associated GHS pictogrammes (GHS07, GHS08, GHS09) emphasize the need for proper handling protocols. Its ADR Class 6.1 classification requires specialized transportation procedures for safe distribution. Key industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, polymer production, and specialty chemical manufacturing. The compound serves as a precursor in the development of various organic compounds, sharing certain synthetic pathways with substances like 4-[(4-aminophenyl)methyl]aniline in pharmaceutical intermediate chemistry. Its reducing properties make it valuable in specific industrial processes where controlled chemical reduction is required. OYSI maintains reliable supply chains for benzene-1,3-diol, ensuring consistent availability for European industrial customers requiring this essential chemical intermediate.
Safety & Classification
Acute Tox. 4; STOT SE 1; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1B; Aquatic Acute 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2876 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Resorcinol, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is benzene-1,3-diol?
Benzene-1,3-diol is an organic chemical compound with the molecular formula C6H6O2 and CAS number 108-46-3. It is a dihydroxybenzene isomer, commonly known as resorcinol, featuring two hydroxyl groups attached to a benzene ring in meta positions. With a molecular weight of 110.11 g/mol, this aromatic compound serves as an important industrial intermediate in various chemical processes and manufacturing applications.
What are the physicochemical properties of benzene-1,3-diol?
Benzene-1,3-diol appears as white to light beige crystalline needles or powder at room temperature. It has a characteristic sweet odor and exhibits excellent water solubility due to its hydroxyl groups. The compound has a melting point around 110°C and is also soluble in alcohol and ether. It tends to darken upon exposure to light and air, requiring proper storage conditions to maintain its quality and appearance.
What is benzene-1,3-diol used for?
Benzene-1,3-diol serves as a key intermediate in the production of adhesives, particularly resorcinol-formaldehyde resins used in wood bonding applications. It is utilized in the manufacture of rubber compounds, hair dyes, pharmaceuticals, and UV absorbers. The chemical industry also employs it in the synthesis of various specialty chemicals, flame retardants, and as a component in certain photographic developers and antiseptic formulations.
How to handle benzene-1,3-diol safely?
Benzene-1,3-diol requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Irrit. 2, Skin Sens. 1B, and STOT SE 1. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or use local exhaust ventilation to minimize inhalation exposure. Avoid skin and eye contact, and prevent dust formation during handling operations.
How to store benzene-1,3-diol correctly?
Benzene-1,3-diol should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and protected from light to prevent discoloration. Store away from incompatible materials such as strong oxidizing agents and bases. Maintain temperatures below 25°C when possible and ensure storage areas are equipped with appropriate spill containment measures and fire protection systems.
What to do in case of contact with benzene-1,3-diol?
Benzene-1,3-diol contact requires immediate action due to its irritant and sensitizing properties. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. Seek medical advice if symptoms persist or if large amounts were involved.
How to dispose of benzene-1,3-diol appropriately?
Benzene-1,3-diol disposal must comply with local and national hazardous waste regulations due to its classification as harmful and aquatic pollutant. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into drains, waterways, or soil. Small laboratory quantities may be disposed of through approved incineration facilities. Always consult local environmental authorities for specific disposal requirements in your region.
How to transport benzene-1,3-diol?
Benzene-1,3-diol is classified under ADR as Class 6.1 (Toxic substances), Packing Group III, indicating moderate danger during transport. It requires appropriate UN-specification packaging and proper labeling with GHS07, GHS08, and GHS09 pictograms. Transport documents must include the correct shipping name and UN number. Vehicles must carry appropriate emergency equipment and drivers need ADR training for Class 6.1 substances.
Is benzene-1,3-diol subject to particular regulations?
Benzene-1,3-diol is subject to REACH regulation requiring registration for import/manufacture above 1 tonne annually in the EU. It falls under CLP classification with specific labeling requirements including 'Danger' signal word and appropriate hazard statements. While not currently listed as SVHC, its toxic and sensitizing properties require compliance with occupational exposure limits and worker protection measures under various national chemical safety regulations.
Where to buy benzene-1,3-diol in Europe?
Benzene-1,3-diol is available through OYSI, a European distributor specializing in technical chemicals for industrial applications. As an established chemical supplier, OYSI can provide this compound with appropriate documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, packaging options, and delivery throughout Europe, ensuring you receive quality products meeting European standards and regulations.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.