Toluene

C7H8

toluene

CAS108-88-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
108-88-3
EC Number
203-625-9
UN Number
1294
Index Number
601-021-00-3
PubChem CID
1140

Physical-chemical properties

Molecular Formula
C7H8
Molar Mass
92.14 g/mol
IUPAC Name
toluene

Chemical Identifiers

InChI
InChI=1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
InChI Key
YXFVVABEGXRONW-UHFFFAOYSA-N

Overview

Toluene (CAS 108-88-3) is an aromatic hydrocarbon solvent with excellent dissolving properties and moderate volatility. Toluene is a clear, colorless liquid with a distinctive sweet, benzene-like odor that occurs naturally in crude oil and is produced during the refining process. As a member of the BTEX group (benzene, toluene, ethylbenzene, and xylenes), this aromatic compound serves as a fundamental building block in petrochemical manufacturing and industrial applications. With its molecular formula C7H8 and molecular weight of 92.14 g/mol, toluene consists of a benzene ring with a single methyl group attachment, giving it unique solvent characteristics that distinguish it from related compounds like ethylbenzene. The substance exhibits excellent solvent properties for oils, resins, rubber, and many organic compounds, while maintaining relatively low water solubility. However, toluene requires careful handling due to its classification as a flammable liquid (Category 2) and potential health hazards including reproductive toxicity and aspiration toxicity. The GHS02, GHS07, and GHS08 pictograms indicate fire, health, and serious health hazards respectively, necessitating appropriate safety measures during storage, handling, and transportation under ADR Class 3 regulations. Industrial applications include paint and coating formulations, where toluene serves as a solvent and thinner, adhesive manufacturing for its bonding enhancement properties, and chemical synthesis as a feedstock for producing benzene derivatives and other aromatic compounds. The pharmaceutical and rubber industries also utilize toluene in various production processes. OYSI provides high-quality toluene to meet diverse industrial requirements across European markets, ensuring reliable supply for manufacturing and chemical processing applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT SE 3; STOT RE 2 *; Skin Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H304

May be fatal if swallowed and enters airways.

H336

May cause drowsiness or dizziness.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1294
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameToluen
Marine PollutantNo

Frequently Asked Questions

What is toluene?

Toluene is an aromatic hydrocarbon with the chemical formula C7H8 and CAS number 108-88-3. It is a clear, colorless liquid with a distinctive sweet smell, derived from petroleum or coal tar. With a molecular weight of 92.14 g/mol, toluene belongs to the benzene family and is widely used as an industrial solvent and chemical intermediate in various manufacturing processes.

What are the physicochemical properties of toluene?

Toluene is a colorless, flammable liquid with a characteristic aromatic odor at room temperature. It has a boiling point of 110.6°C and a melting point of -95°C. Toluene is practically insoluble in water but miscible with most organic solvents including alcohols, ethers, and hydrocarbons. It has a density of 0.87 g/cm³ and readily evaporates, forming flammable vapor-air mixtures.

What is toluene used for?

Toluene is primarily used as a solvent in paints, coatings, adhesives, and printing inks due to its excellent dissolving properties. It serves as a raw material for producing benzene, phenol, and other chemicals. In the pharmaceutical industry, toluene is used as an intermediate for synthesizing various compounds. Additionally, it finds applications in rubber processing, leather tanning, and as a fuel additive to improve octane ratings.

How to handle toluene safely?

Toluene requires careful handling due to its flammable and toxic properties. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection in poorly ventilated areas. Work in well-ventilated spaces away from ignition sources, heat, and sparks. Avoid skin contact and inhalation as toluene can cause irritation and central nervous system effects. Ground containers during transfer to prevent static electricity buildup.

How to store toluene correctly?

Toluene must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers grounded and use explosion-proof electrical equipment in storage areas. Store away from oxidizing agents and incompatible materials. Maintain temperatures below 30°C and ensure adequate fire suppression systems are in place. Use appropriate containment measures to prevent environmental contamination.

What to do in case of contact with toluene?

In case of skin contact with toluene, immediately remove contaminated clothing and wash affected areas with soap and water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention if breathing difficulties occur. For eye contact, flush with clean water for 15 minutes and remove contact lenses if present. If ingested, do not induce vomiting and seek immediate medical attention.

How to dispose of toluene properly?

Toluene must be disposed of as hazardous waste according to local and national regulations. Do not pour down drains, sewers, or onto the ground as it can contaminate water sources and soil. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities can often be recycled through solvent recovery programs. Always check local environmental regulations and obtain proper waste disposal documentation.

How to transport toluene?

Toluene is classified as ADR Class 3 (flammable liquid), Packing Group II for transportation purposes. It must be transported in UN-approved containers with proper hazard labels and documentation. Vehicles must carry appropriate fire extinguishing equipment and emergency response information. Drivers require hazardous materials training and ADR certification. Ensure containers are properly secured and protected from damage during transport.

Is toluene subject to specific regulations?

Toluene is subject to various European regulations including REACH registration and CLP classification requirements. It is classified as Flam. Liq. 2, Repr. 2, Asp. Tox. 1, STOT SE 3, STOT RE 2, and Skin Irrit. 2 under CLP regulation. While not currently listed as an SVHC substance, its use may be restricted in certain consumer applications. Workplace exposure limits apply, and proper risk assessments are mandatory for industrial use.

Where to buy toluene in Europe?

Toluene is available through OYSI, a European chemical distributor specializing in technical-grade chemicals for industrial applications. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical supplier, OYSI ensures product quality and can assist with technical specifications, handling requirements, and regulatory guidance for toluene procurement and use.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.