Toluene

C7H8

toluene

CAS108-88-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
108-88-3
EC Number
203-625-9
UN Number
1294
Index Number
601-021-00-3
PubChem CID
1140

Physical-chemical properties

Molecular Formula
C7H8
Molar Mass
92.14 g/mol
IUPAC Name
toluene

Chemical Identifiers

InChI
InChI=1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
InChI Key
YXFVVABEGXRONW-UHFFFAOYSA-N

Overview

Toluene (CAS 108-88-3) is an aromatic hydrocarbon solvent with high dissolving power and moderate volatility, widely used in industrial applications. This colorless liquid, with the molecular formula C7H8, represents one of the most important aromatic solvents in the chemical industry. Toluene is characterized by its distinctive sweet, benzene-like odor and excellent solvency properties for a wide range of organic compounds. As a member of the BTEX family (benzene, toluene, ethylbenzene, xylenes), it shares similar chemical properties with related compounds like ethylbenzene and styrene, though it offers distinct advantages in specific applications due to its unique molecular structure. The substance exhibits significant flammability characteristics, classified as Flammable Liquid Category 2 under GHS regulations, requiring careful handling and appropriate safety measures. Its reproductive toxicity classification (Repr. 2) and aspiration toxicity potential (Asp. Tox. 1) necessitate strict occupational health controls and proper ventilation systems during use. The compound also presents skin irritation risks and specific target organ toxicity concerns, making personal protective equipment essential for safe handling. Toluene finds extensive application as a solvent in paint and coating formulations, where its excellent dissolving properties for resins and polymers make it invaluable. The chemical industry utilizes toluene as a key intermediate in the production of benzene derivatives and various aromatic compounds. Additionally, it serves as an important component in adhesive formulations, particularly in contact adhesives and rubber cements, where its rapid evaporation rate and strong solvency are crucial. OYSI maintains reliable supply chains for toluene across European markets, ensuring consistent availability for industrial customers requiring high-quality aromatic solvents.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT SE 3; STOT RE 2 *; Skin Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H304

May be fatal if swallowed and enters airways.

H336

May cause drowsiness or dizziness.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1294
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameToluen
Marine PollutantNo

Frequently Asked Questions

What is toluene?

Toluene is an aromatic hydrocarbon with the molecular formula C7H8 and CAS number 108-88-3. It is a colorless liquid derived from petroleum or coal tar, characterized by a sweet, benzene-like odor. With a molecular weight of 92.14 g/mol, toluene is widely used as an industrial solvent and chemical intermediate. It belongs to the BTEX group of compounds and is classified as a flammable liquid with reproductive toxicity properties under GHS regulations.

What are the physicochemical properties of toluene?

Toluene is a clear, colorless liquid at room temperature with a characteristic sweet, aromatic odor reminiscent of paint thinner. It has a boiling point of 110.6°C and is poorly soluble in water but miscible with most organic solvents including alcohols, ethers, and hydrocarbons. Toluene has a density of approximately 0.87 g/cm³, making it lighter than water, and exhibits high volatility with significant vapor pressure at ambient temperatures.

What is toluene used for?

Toluene serves as a versatile industrial solvent in paint thinners, adhesives, rubber, and printing inks. It is a key feedstock in petrochemical manufacturing for producing benzene, xylenes, and other aromatic compounds. The chemical industry uses toluene to synthesize toluene diisocyanate (TDI) for polyurethane production, benzoic acid, and various pharmaceuticals. Additionally, it functions as an octane booster in gasoline blending and finds applications in the production of explosives like TNT.

How to handle toluene safely?

Toluene requires careful handling due to its flammable and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in poorly ventilated areas. Work in well-ventilated spaces or under fume extraction systems to minimize inhalation exposure. Eliminate ignition sources as toluene vapors can form explosive mixtures with air. Avoid direct skin contact and use appropriate containment measures to prevent spills and environmental release.

How to store toluene correctly?

Toluene must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use original containers or approved flammable liquid storage tanks made of compatible materials. Keep containers tightly sealed to prevent vapor escape and maintain temperatures below 25°C when possible. Store away from oxidizing agents, strong acids, and incompatible materials. Ensure proper grounding and bonding during transfer operations to prevent static electricity buildup.

What to do in case of contact with toluene?

Immediate action is required following toluene exposure. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move the person to fresh air and provide oxygen if breathing is difficult. For ingestion, do not induce vomiting and seek immediate medical assistance.

How to dispose of toluene properly?

Toluene disposal must comply with local and national hazardous waste regulations as it is classified as dangerous waste. Contact licensed hazardous waste disposal companies for proper collection and treatment. Never dispose of toluene down drains, sewers, or onto soil as it can contaminate groundwater. Small quantities may be suitable for solvent recovery programs, while larger volumes typically require incineration at specialized facilities equipped with appropriate emission controls and waste treatment systems.

How to transport toluene?

Toluene is classified under ADR regulations as Class 3 (flammable liquid), Packing Group II, requiring specific transport protocols. Use approved containers and packaging that meet UN specifications for flammable liquids. Vehicles must carry appropriate placarding, emergency response information, and comply with tunnel restrictions. Drivers need ADR training certification, and transport documentation must include proper shipping names, hazard classes, and emergency contact information for regulatory compliance.

Is toluene subject to specific regulations?

Toluene is subject to comprehensive European chemical regulations under REACH and CLP. It is classified with multiple hazard classes including flammable liquid, reproductive toxicity, and aspiration toxicity, requiring safety data sheets and hazard labeling. While not currently listed as an SVHC substance, toluene use is restricted in certain consumer applications. Industrial users must comply with occupational exposure limits, emission controls, and worker health surveillance requirements under various EU directives.

Where to buy toluene in Europe?

Toluene is available through OYSI, a European distributor of technical chemicals serving industrial customers across the continent. As a specialized chemical distributor, OYSI provides quality toluene with proper documentation, safety data sheets, and regulatory compliance support. Professional buyers can access technical-grade toluene suitable for various industrial applications through OYSI's distribution network, ensuring reliable supply chain management and customer service for European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.