Hexane

C6H14

hexane

CAS110-54-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

Consulting for Hexane

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Identification

CAS Number
110-54-3
EC Number
203-777-6
UN Number
1208
Index Number
601-037-00-0
PubChem CID
8058

Physical-chemical properties

Molecular Formula
C6H14
Molar Mass
86.18 g/mol
IUPAC Name
hexane

Chemical Identifiers

InChI
InChI=1S/C6H14/c1-3-5-6-4-2/h3-6H2,1-2H3
InChI Key
VLKZOEOYAKHREP-UHFFFAOYSA-N

Overview

Hexane (CAS 110-54-3) is a saturated aliphatic hydrocarbon with six carbon atoms, commonly used as an industrial solvent and extraction medium. This colorless, volatile liquid belongs to the alkane family and serves as a crucial industrial solvent across multiple sectors. With its molecular formula C6H14 and molar mass of 86.18 g/mol, hexane exhibits excellent solvent properties for non-polar compounds, making it particularly valuable in extraction processes and chemical manufacturing. The substance is characterized by its low boiling point, high volatility, and distinctive petroleum-like odor. From a safety perspective, hexane requires careful handling due to its classification under multiple hazard categories. It presents significant risks as a flammable liquid (Category 2), reproductive toxicant (Category 2), and aspiration hazard (Category 1). The substance can cause skin irritation and poses risks to both specific target organs and the nervous system through repeated exposure. Its environmental classification as Aquatic Chronic 2 indicates potential long-term effects on aquatic ecosystems. The ADR Class 3 classification reflects its flammable nature during transportation. Industrial applications of hexane span several key sectors. It serves as a primary extraction solvent in vegetable oil processing, effectively separating oils from seeds and plant materials. The pharmaceutical and chemical industries utilize hexane for purification processes and as a reaction medium. Additionally, it functions as a cleaning agent in specialized industrial applications. Unlike related compounds such as propylbenzene or more complex structures like 3-ethyl-3-methylpentane, hexane's straight-chain structure provides optimal solvent characteristics for specific extraction processes. OYSI maintains reliable supplies of technical-grade hexane to support European industrial operations, ensuring consistent quality and regulatory compliance for professional applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT SE 3; STOT RE 1; Skin Irrit. 2; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H304

May be fatal if swallowed and enters airways.

H336

May cause drowsiness or dizziness.

H372

Causes damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1208
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameHexan
Marine PollutantNo

Frequently Asked Questions

What is hexane?

Hexane is a saturated hydrocarbon with the molecular formula C6H14 and CAS number 110-54-3. It belongs to the alkane family and has a molecular weight of 86.18 g/mol. This chemical compound is classified as a flammable liquid with significant health hazards including reproductive toxicity, aspiration toxicity, and organ damage potential. Hexane requires careful handling due to its dangerous properties.

What are the physicochemical properties of hexane?

Hexane is a colorless liquid with a gasoline-like odor at room temperature. It has a low boiling point and high volatility, making it easily evaporable. The substance is highly flammable and practically insoluble in water but miscible with most organic solvents. Its low viscosity and non-polar nature make it an excellent solvent for extracting oils and fats from various materials.

What is hexane used for?

Hexane is primarily used as an industrial solvent for extracting vegetable oils from seeds and nuts in food processing. It serves as a cleaning agent for removing grease and oil in manufacturing processes, and as a laboratory solvent for chromatography and extraction procedures. Additionally, hexane is used in the production of adhesives, textiles, and as a component in some specialty chemical formulations.

How to handle hexane safely?

Hexane requires strict safety measures including wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Eliminate all ignition sources as hexane vapors can ignite easily. Avoid skin contact and ensure emergency shower and eyewash stations are readily accessible during handling operations.

How to store hexane correctly?

Hexane must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use only approved containers and storage cabinets designed for flammable liquids. Keep containers tightly sealed to prevent vapor escape and store away from incompatible materials such as strong oxidizing agents. Maintain storage temperature below 25°C and implement appropriate fire suppression systems in storage areas.

What to do in case of contact with hexane?

Hexane exposure requires immediate action: for skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately and provide respiratory support if needed. For ingestion, do not induce vomiting due to aspiration hazard and seek immediate medical care.

How to dispose of hexane appropriately?

Hexane disposal must comply with local and national hazardous waste regulations as it cannot be disposed of with regular waste. The substance should be collected in appropriate containers and handed over to licensed hazardous waste disposal companies. Never pour hexane down drains or sewers, and avoid evaporation into the atmosphere. Consider recovery and recycling options where economically viable to minimize environmental impact.

How to transport hexane?

Hexane is classified under ADR Class 3 (flammable liquids) Packing Group II, requiring specific transport regulations compliance. Use UN-approved packaging and ensure proper hazard labeling with appropriate placarding on transport vehicles. Drivers must hold ADR certification for dangerous goods transport. Vehicles should be equipped with appropriate fire extinguishers and emergency equipment, and routes should avoid populated areas where possible.

Is hexane subject to specific regulations?

Hexane is subject to comprehensive European chemical regulations under REACH and CLP classifications. It carries multiple hazard classifications including reproductive toxicity (Repr. 2) and specific target organ toxicity (STOT RE 1), requiring detailed safety data sheets and risk assessments. While not currently listed as a SVHC substance, its hazardous properties mandate strict workplace exposure limits and comprehensive risk management measures.

Where to buy hexane in Europe?

Hexane is available through OYSI, a European distributor specializing in technical chemical products. As a professional chemical supplier, OYSI can provide hexane with appropriate documentation including safety data sheets and certificates of analysis. Contact OYSI directly to discuss your specific requirements, quantities, and delivery options across European markets while ensuring compliance with all applicable regulations and safety standards.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.