Propyl formate

C4H8O2

propyl formate

CAS110-74-7
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
110-74-7
EC Number
203-798-0
UN Number
1281
Index Number
607-016-00-2
PubChem CID
8073

Physical-chemical properties

Molecular Formula
C4H8O2
Molar Mass
88.11 g/mol
IUPAC Name
propyl formate

Chemical Identifiers

InChI
InChI=1S/C4H8O2/c1-2-3-6-4-5/h4H,2-3H2,1H3
InChI Key
KFNNIILCVOLYIR-UHFFFAOYSA-N

Overview

Propyl formate (CAS 110-74-7) is an aliphatic ester compound with characteristic fruity odor and excellent solvent properties for industrial applications. This colorless liquid ester belongs to the formate family and serves as a versatile chemical intermediate in various industrial processes. With its molecular formula C4H8O2 and molecular weight of 88.11 g/mol, propyl formate exhibits favorable physicochemical properties that make it valuable for specialized technical applications. The compound is synthesized through the esterification of formic acid with propanol, resulting in a product with good volatility and moderate polarity characteristics. From a safety perspective, propyl formate is classified as a flammable liquid (Category 2) requiring careful handling procedures. The substance presents eye irritation hazards (Category 2) and specific target organ toxicity concerns (Category 3), necessitating appropriate personal protective equipment during use. Transport regulations classify it under ADR Class 3 for flammable liquids, and the GHS02 and GHS07 pictograms with the danger signal word indicate the required safety precautions for storage and handling. Industrial applications of propyl formate include its use as a solvent in coating formulations, particularly where controlled evaporation rates are desired. The compound also finds application in the production of specialty chemicals and as an intermediate in pharmaceutical synthesis. Unlike heavier aromatic solvents such as ethylbenzene or styrene, propyl formate offers lower toxicity profiles while maintaining effective solvency characteristics for specific formulations. OYSI maintains reliable supply chains for propyl formate to support European industrial customers requiring consistent quality and technical support for their chemical processing needs.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; STOT SE 3; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H335

May cause respiratory irritation.

H336

May cause drowsiness or dizziness.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1281
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NamePropylformiat
Marine PollutantNo

Frequently Asked Questions

What is propyl formate?

Propyl formate is an organic chemical compound with the molecular formula C4H8O2 and CAS number 110-74-7. This ester has a molecular weight of 88.11 g/mol and belongs to the formate family of compounds. It is classified as a flammable liquid with specific hazard properties including eye irritation and specific target organ toxicity. The substance requires careful handling due to its flammable nature and potential health effects upon exposure.

What are the physicochemical properties of propyl formate?

Propyl formate is a colorless liquid with a characteristic fruity, pleasant ester odor reminiscent of plums or apples. It has a relatively low boiling point and is moderately soluble in water while being miscible with most organic solvents. The compound exhibits typical ester properties and has a density lower than water. Its volatility and flammable characteristics make it important to consider ventilation and ignition sources during handling.

What is propyl formate used for?

Propyl formate is primarily used as a solvent in various industrial applications including coatings, inks, and adhesive formulations. It serves as a flavoring agent in the food industry due to its pleasant fruity aroma and is utilized in perfumery and cosmetic applications. The compound is also employed as an intermediate in organic synthesis and as a solvent for cellulose-based materials and resins in manufacturing processes.

How to handle propyl formate safely?

Propyl formate requires appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume extraction systems due to vapor hazards. Eliminate ignition sources as the substance is highly flammable. Avoid breathing vapors and ensure emergency eyewash stations and safety showers are accessible in work areas.

How to store propyl formate correctly?

Propyl formate must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources, sparks, and open flames. Storage areas should be equipped with appropriate fire suppression systems and maintained below recommended temperature limits. Keep containers away from incompatible materials such as strong oxidizers and acids. Ensure proper grounding and bonding procedures when transferring the material to prevent static electricity buildup.

What to do in case of contact with propyl formate?

Propyl formate exposure requires immediate action depending on the contact route. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention due to its eye irritant properties. If skin contact occurs, wash thoroughly with soap and water. In case of inhalation, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention while providing safety data sheet information to medical personnel.

How to dispose of propyl formate appropriately?

Propyl formate disposal must comply with local, national, and international waste regulations as it is classified as hazardous waste. The substance should never be poured down drains or released into the environment. Disposal should be arranged through licensed hazardous waste contractors who can ensure proper treatment, incineration, or recycling. Empty containers may retain hazardous residues and require proper cleaning or disposal through appropriate waste management channels.

How to transport propyl formate?

Propyl formate is classified under ADR as Class 3 (flammable liquids), Packing Group II, indicating moderate danger level for transportation. Packages must comply with UN specifications and bear appropriate hazard labels including flammable liquid markings. Transport vehicles require proper ventilation, fire extinguishing equipment, and trained drivers with ADR certification. Shipping documentation must include proper shipping names, hazard classifications, and emergency response information.

Is propyl formate subject to specific regulations?

Propyl formate is regulated under European REACH and CLP regulations requiring registration and proper classification and labeling. The substance is not currently listed as a Substance of Very High Concern (SVHC). Suppliers must provide safety data sheets and ensure proper hazard communication through GHS pictograms GHS02 and GHS07 with the signal word 'Danger'. Users must comply with occupational exposure limits and workplace safety requirements in their respective jurisdictions.

Where to buy propyl formate in Europe?

Propyl formate is available through OYSI, a European distributor of chemical products specializing in technical chemicals for industrial applications. OYSI provides reliable supply chains across Europe with proper documentation including certificates of analysis and safety data sheets. As an established chemical distributor, OYSI ensures compliance with European regulations and offers technical support for proper handling and application of propyl formate in various industrial sectors.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.