Hexane-1,6-diamine

C6H16N2

hexane-1,6-diamine

CAS124-09-4
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
124-09-4
EC Number
204-679-6
UN Number
2280
Index Number
612-104-00-9
PubChem CID
16402

Physical-chemical properties

Molecular Formula
C6H16N2
Molar Mass
116.20 g/mol
IUPAC Name
hexane-1,6-diamine

Chemical Identifiers

InChI
InChI=1S/C6H16N2/c7-5-3-1-2-4-6-8/h1-8H2
InChI Key
NAQMVNRVTILPCV-UHFFFAOYSA-N

Overview

Hexane-1,6-diamine (CAS 124-09-4) is a linear aliphatic diamine compound with strong basic properties and industrial polymer applications. This versatile chemical intermediate, also known by its IUPAC designation hexane-1,6-diamine, serves as a crucial building block in various industrial processes. With the molecular formula C6H16N2 and a molecular weight of 116.2 g/mol, this compound features two primary amine groups positioned at opposite ends of a six-carbon chain, giving it distinctive chemical reactivity and cross-linking capabilities. The substance presents significant safety considerations, classified under multiple hazard categories including acute toxicity and skin corrosion. Its classification as Skin Corr. 1B with GHS pictograms GHS05 and GHS07 indicates the corrosive nature requiring careful handling protocols. The ADR Class 8 designation reflects its corrosive properties during transportation, necessitating specialized packaging and safety measures. Hexane-1,6-diamine finds primary applications in polyamide synthesis, where it acts as a key monomer in nylon production, particularly in creating high-performance engineering plastics. The chemical industry also utilizes this diamine in epoxy curing systems and as an intermediate for specialty chemicals production. Its bifunctional nature makes it valuable in cross-linking applications, similar to how other amines like N-cyclohexylcyclohexanamine serve in curing systems, though with different performance characteristics. The compound's linear structure and dual amine functionality distinguish it from related compounds such as phenylmethanamine, offering specific advantages in polymer chain extension and network formation applications. OYSI maintains reliable supply chains for hexane-1,6-diamine, ensuring consistent availability for European industrial customers requiring this essential chemical intermediate.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2280
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameHexamethylendiamin, fest
Marine PollutantNo

Frequently Asked Questions

What is hexane-1,6-diamine?

Hexane-1,6-diamine is an organic chemical compound with the molecular formula C6H16N2 and CAS number 124-09-4. This diamine features two amino groups (-NH2) positioned at opposite ends of a six-carbon chain, making it a linear aliphatic diamine. With a molecular weight of 116.2 g/mol, it serves as an important building block in polymer chemistry and industrial applications. The compound is classified as hazardous with corrosive properties and requires careful handling protocols.

What are the physicochemical properties of hexane-1,6-diamine?

Hexane-1,6-diamine is typically a colorless to pale yellow crystalline solid at room temperature with a characteristic amine odor. The compound is highly soluble in water and polar solvents due to its amino groups, which can form hydrogen bonds. It has a relatively low molecular weight of 116.2 g/mol and exhibits basic properties due to the presence of two primary amine groups that can accept protons in aqueous solutions.

What is hexane-1,6-diamine used for?

Hexane-1,6-diamine is primarily used as a monomer in the production of nylon-6,6, one of the most important engineering plastics. It serves as a key building block for polyamide synthesis, creating strong, durable polymers used in automotive parts, textiles, and industrial components. Additionally, it functions as a curing agent for epoxy resins, a cross-linking agent in polymer chemistry, and an intermediate in the synthesis of various specialty chemicals and additives.

How to handle hexane-1,6-diamine safely?

Hexane-1,6-diamine requires careful handling due to its corrosive properties (Skin Corr. 1B) and acute toxicity. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation or use respiratory protection to avoid inhalation exposure. Work in a well-ventilated area or fume hood, avoid direct skin and eye contact, and have emergency eyewash and safety shower facilities readily available. Handle with chemical-resistant tools and equipment.

How to store hexane-1,6-diamine correctly?

Hexane-1,6-diamine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and properly labeled with hazard information. Store away from incompatible materials such as strong acids, oxidizing agents, and moisture-sensitive compounds. Maintain storage temperatures as recommended by the supplier and ensure storage areas have appropriate spill containment measures and emergency equipment accessible.

What to do in case of contact with hexane-1,6-diamine?

Hexane-1,6-diamine contact requires immediate emergency response due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush affected area with plenty of water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. In all cases, seek immediate medical attention and provide safety data sheet information to medical personnel.

How to dispose of hexane-1,6-diamine appropriately?

Hexane-1,6-diamine disposal must comply with local, national, and international waste regulations as it is classified as hazardous waste. Do not pour down drains or release into the environment. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require neutralization under controlled conditions before disposal. Always consult current waste disposal regulations and safety data sheets for specific disposal requirements in your jurisdiction.

How to transport hexane-1,6-diamine?

Hexane-1,6-diamine is classified under ADR Class 8 (Corrosive substances), Packing Group III for transportation. It requires appropriate corrosive substance packaging, labeling with UN identification numbers, and proper shipping documentation. Transport vehicles must carry appropriate placarding and emergency response information. Only use UN-specification packaging and ensure compliance with dangerous goods transportation regulations. Drivers must have proper training and certification for transporting corrosive materials.

Is hexane-1,6-diamine subject to particular regulations?

Hexane-1,6-diamine is subject to various European chemical regulations including REACH registration requirements and CLP classification and labeling obligations. It is not currently listed as a Substance of Very High Concern (SVHC) under REACH. Companies must comply with safety data sheet requirements, workplace exposure limits, and proper hazard communication. Industrial users may need to implement risk management measures and ensure downstream user information requirements are met according to chemical safety regulations.

Where to buy hexane-1,6-diamine in Europe?

Hexane-1,6-diamine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures quality products that meet industrial specifications and provides technical support for safe handling and application guidance. Contact OYSI directly for availability, specifications, and delivery options in your European location.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.