2-(diethylamino)ethanol

C6H15NO

CAS100-37-8
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
100-37-8
EC Number
202-845-2
UN Number
2686
Index Number
603-048-00-6
PubChem CID
7497

Physical-chemical properties

Molecular Formula
C6H15NO
Molar Mass
117.19 g/mol
IUPAC Name
2-(diethylamino)ethanol

Chemical Identifiers

InChI
InChI=1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
InChI Key
BFSVOASYOCHEOV-UHFFFAOYSA-N

Overview

2-(diethylamino)ethanol (CAS 100-37-8) is a tertiary amine alcohol compound with both basic amine and hydroxyl functional groups, exhibiting significant corrosive and flammable properties. This bifunctional organic compound serves as an important intermediate in various chemical synthesis processes and industrial applications. The molecule combines the reactivity of a tertiary amine with the versatility of a primary alcohol, making it valuable for numerous chemical transformations. Its molecular structure, featuring diethylamino and ethanol moieties, provides both nucleophilic and electrophilic reaction sites that are exploited in pharmaceutical, polymer, and specialty chemical manufacturing. From a safety perspective, 2-(diethylamino)ethanol requires careful handling due to its classification as a flammable liquid and corrosive substance. The compound presents acute toxicity risks through multiple exposure routes and can cause severe skin and eye damage. Its corrosive nature necessitates appropriate personal protective equipment and ventilation systems during handling and processing. The flammable properties require standard fire prevention measures and proper storage away from ignition sources. Industrial applications include its use as a catalyst and curing agent in polyurethane foam production, where its tertiary amine functionality promotes efficient polymerization reactions. The compound also serves as an intermediate in the synthesis of pharmaceuticals and agrochemicals, leveraging its dual functionality for complex molecular construction. In metalworking applications, it functions as a corrosion inhibitor and pH adjustment agent. Related compounds such as 2-(dimethylamino)ethanol share similar applications but offer different reactivity profiles due to their distinct alkyl substituents. OYSI supplies 2-(diethylamino)ethanol to meet diverse industrial requirements across European markets, ensuring consistent quality and reliable delivery for professional applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2686
ADR Class8
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name2-Diethylaminoethanol
Marine PollutantNo

Frequently Asked Questions

What is 2-(diethylamino)ethanol?

2-(diethylamino)ethanol is a tertiary amine alcohol with the molecular formula C6H15NO and CAS number 100-37-8. This organic compound has a molecular weight of 117.19 g/mol and combines both amine and alcohol functional groups in its structure. It appears as a clear, colorless to slightly yellow liquid with an ammonia-like odor and is miscible with water and most organic solvents due to its polar nature.

What are the physicochemical properties of 2-(diethylamino)ethanol?

2-(diethylamino)ethanol is a clear, colorless to pale yellow liquid at room temperature with a characteristic ammonia-like or fishy odor. The compound has a molecular weight of 117.19 g/mol and is highly soluble in water due to its hydroxyl group. It also dissolves readily in alcohols and other polar organic solvents, making it versatile for various chemical applications and formulations.

What is 2-(diethylamino)ethanol used for?

2-(diethylamino)ethanol is primarily used as a chemical intermediate in pharmaceutical synthesis and as a catalyst in polyurethane foam production. It serves as a corrosion inhibitor in metalworking fluids, an emulsifier in cosmetic formulations, and a neutralizing agent in various chemical processes. The compound is also utilized in the manufacture of surfactants, textile auxiliaries, and as a pH regulator in industrial applications.

How to handle 2-(diethylamino)ethanol safely?

2-(diethylamino)ethanol requires careful handling due to its corrosive and toxic properties. Always wear chemical-resistant gloves, safety goggles, and protective clothing when handling this substance. Work in well-ventilated areas or use local exhaust ventilation to prevent inhalation of vapors. Avoid contact with skin, eyes, and clothing. Keep away from heat sources, sparks, and open flames as it is a flammable liquid.

How to store 2-(diethylamino)ethanol correctly?

2-(diethylamino)ethanol should be stored in tightly sealed containers made of compatible materials in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep away from oxidizing agents, strong acids, and incompatible materials. Storage areas should be equipped with appropriate fire suppression systems and spill containment measures. Maintain storage temperatures below 25°C and protect from direct sunlight to prevent degradation.

What to do in case of contact with 2-(diethylamino)ethanol?

In case of skin contact with 2-(diethylamino)ethanol, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. For eye contact, rinse thoroughly with water for at least 15 minutes and seek immediate medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek medical attention immediately. Always consult a physician in case of exposure.

How to dispose of 2-(diethylamino)ethanol appropriately?

2-(diethylamino)ethanol must be disposed of as hazardous waste according to local, national, and international regulations. Do not pour down drains or release into the environment. Contact licensed waste disposal companies for proper treatment and disposal. Small quantities may be incinerated in approved facilities with appropriate emission controls. Always check current waste classification codes and follow proper packaging and labeling requirements for hazardous waste transport.

How to transport 2-(diethylamino)ethanol?

2-(diethylamino)ethanol is classified under ADR as Class 8 (corrosive substances), Packing Group II. It must be transported in approved packaging that meets UN specification requirements for corrosive liquids. Proper shipping documentation, labeling with corrosive hazard labels, and placarding of transport vehicles are mandatory. Transport should comply with ADR regulations for dangerous goods and be handled by trained personnel with appropriate emergency response procedures.

Is 2-(diethylamino)ethanol subject to specific regulations?

2-(diethylamino)ethanol is regulated under multiple European frameworks including REACH registration requirements and CLP classification as a flammable liquid and corrosive substance. It requires safety data sheets and proper labeling with GHS pictograms (GHS02, GHS05, GHS07). The compound is not currently listed as a SVHC (Substance of Very High Concern) but must comply with occupational exposure limits and environmental protection regulations in EU member states.

Where to buy 2-(diethylamino)ethanol in Europe?

2-(diethylamino)ethanol is available through OYSI, a leading European distributor of specialty chemicals. OYSI provides high-quality chemical products with proper documentation, including safety data sheets and certificates of analysis. As an established supplier in the European market, OYSI ensures compliance with all relevant regulations and can provide technical support for your specific application requirements. Contact OYSI for availability, specifications, and pricing information.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.