Cyclohexanamine
C6H13N
cyclohexanamine
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Identification
- CAS Number
- 108-91-8
- EC Number
- 203-629-0
- UN Number
- 2357
- Index Number
- 612-050-00-6
- PubChem CID
- 7965
Physical-chemical properties
- Molecular Formula
- C6H13N
- Molar Mass
- 99.17 g/mol
- IUPAC Name
- cyclohexanamine
Chemical Identifiers
- InChI
- InChI=1S/C6H13N/c7-6-4-2-1-3-5-6/h6H,1-5,7H2
- InChI Key
- PAFZNILMFXTMIY-UHFFFAOYSA-N
Overview
Cyclohexanamine (CAS 108-91-8) is a cyclic primary aliphatic amine with strong basic properties and characteristic ammonia-like odor. This versatile organic compound, also known by its IUPAC name cyclohexanamine, represents an important building block in chemical synthesis and industrial applications. With the molecular formula C6H13N and a molecular weight of 99.17 g/mol, cyclohexanamine features a cyclohexane ring directly bonded to an amino group, giving it distinctive chemical reactivity patterns typical of primary amines. From a safety perspective, cyclohexanamine requires careful handling due to its classification under multiple hazard categories. The substance carries a "Danger" signal word and displays several GHS pictograms including flammability (GHS02), health hazard (GHS08), exclamation mark (GHS07), and corrosion (GHS05) symbols. Its classification as Skin Corr. 1B indicates severe skin corrosive properties, while the Acute Tox. 4 rating reflects moderate acute toxicity concerns. The compound is also classified as Repr. 2, indicating suspected reproductive toxicity, and Flam. Liq. 3 for flammable liquid properties. For transportation, it falls under ADR Class 8 as a corrosive substance. In industrial applications, cyclohexanamine serves primarily as an intermediate in pharmaceutical synthesis, rubber processing chemicals, and corrosion inhibitor formulations. Its chemical structure relates it to other important amines like ethane-1,2-diamine, though cyclohexanamine's cyclic structure provides different reactivity profiles. The compound also finds use in the production of fungicides and as a curing agent for epoxy resins. OYSI maintains reliable supply chains for cyclohexanamine to support diverse industrial requirements across Europe.
Safety & Classification
Flam. Liq. 3; Repr. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B
GHS Pictograms
Flame
GHS02
Flammable. May ignite on contact with air, water, or heat sources.
Health Hazard
GHS08
Serious health hazard. May cause cancer, organ damage, or genetic defects.
Exclamation Mark
GHS07
Harmful. May cause irritation, allergic reactions, or drowsiness.
Corrosion
GHS05
Corrosive. Causes severe skin burns and eye damage.
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2357 |
| ADR Class | 8 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Cyclohexylamin |
| Marine Pollutant | No |
Frequently Asked Questions
What is cyclohexanamine?
Cyclohexanamine is an organic compound with the molecular formula C6H13N and a molecular weight of 99.17 g/mol. It is a primary aliphatic amine derived from cyclohexane, where one hydrogen atom is replaced by an amino group (-NH2). This chemical compound appears as a colorless to pale yellow liquid with a strong fishy, ammonia-like odor. Cyclohexanamine is classified as a hazardous substance with multiple danger classes including flammability, acute toxicity, skin corrosion, and reproductive toxicity.
What are the physicochemical properties of cyclohexanamine?
Cyclohexanamine is a colorless to pale yellow liquid at room temperature with a characteristic strong, fishy, ammonia-like odor. It has a molecular weight of 99.17 g/mol and is highly soluble in water and most organic solvents. The compound is hygroscopic, meaning it readily absorbs moisture from air. It has a boiling point around 134°C and is volatile at room temperature. Cyclohexanamine is basic in nature due to its amino group and can form salts with acids.
What is cyclohexanamine used for?
Cyclohexanamine is primarily used as an intermediate in chemical synthesis and manufacturing processes. It serves as a key raw material in the production of synthetic rubber, particularly in vulcanization accelerators. The compound is also utilized in the manufacture of corrosion inhibitors, dyes, and pharmaceuticals. Additionally, it finds application in the production of insecticides and fungicides. In industrial settings, cyclohexanamine is used as a building block for various specialty chemicals and polymer additives.
How to handle cyclohexanamine safely?
Cyclohexanamine requires careful handling due to its corrosive and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face shield, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin, eyes, and clothing. Use appropriate ventilation systems and avoid generating vapors. Handle containers carefully to prevent spills and always use proper lifting techniques. Emergency eyewash stations and safety showers should be readily accessible.
How to store cyclohexanamine correctly?
Cyclohexanamine must be stored in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers tightly closed and store below 25°C to minimize vapor generation. The substance should be kept away from incompatible materials such as strong acids, oxidizing agents, and reactive metals. Storage areas should have appropriate fire suppression systems and be constructed of compatible materials. Containers should be properly labeled and stored in secondary containment to prevent environmental contamination in case of leaks.
What to do in case of contact with cyclohexanamine?
Cyclohexanamine exposure requires immediate action due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush affected area with plenty of water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for at least 15 minutes while holding eyelids open. If inhaled, move person to fresh air and seek medical attention if breathing difficulties occur. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure incident.
How to dispose of cyclohexanamine appropriately?
Cyclohexanamine disposal must comply with local, national, and international environmental regulations as it is classified as hazardous waste. The substance should never be discharged into drains, water sources, or soil. Professional hazardous waste disposal companies should handle the disposal process through authorized treatment facilities. Small quantities may require neutralization before disposal, but this should only be done by trained personnel. Container disposal must also follow hazardous waste protocols, including proper labeling and documentation for waste tracking purposes.
How to transport cyclohexanamine?
Cyclohexanamine is classified as ADR Class 8 (corrosive substances) with Packing Group II, indicating significant transport hazards. Transportation requires UN-approved packaging and proper hazard labeling with corrosive substance markings. Vehicles must carry appropriate emergency equipment and documentation. Drivers need specialized training for hazardous materials transport. The substance requires segregation from incompatible materials during transport and must be secured to prevent container damage. Emergency response information must accompany shipments, and transport routes should avoid populated areas where possible.
Is cyclohexanamine subject to specific regulations?
Cyclohexanamine is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance must be properly classified and labeled according to GHS standards with appropriate pictograms (GHS02, GHS05, GHS07, GHS08). It falls under reproductive toxicity Category 2 regulations, requiring special handling protocols. Industrial users must implement risk management measures and maintain safety data sheets. The compound may be subject to additional restrictions depending on specific applications and local regulations governing toxic and corrosive substances.
Where to buy cyclohexanamine in Europe?
Cyclohexanamine is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substance supply. As a professional chemical distributor, OYSI provides cyclohexanamine with proper documentation, safety data sheets, and regulatory compliance support. The company serves industrial customers across Europe with reliable supply chains for specialty chemicals. Due to the hazardous nature of cyclohexanamine, purchases typically require proper licensing and demonstrated technical competence. Contact OYSI directly for availability, specifications, and technical support regarding cyclohexanamine procurement.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.