2-hexoxyethanol

C8H18O2

CAS112-25-4
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
112-25-4
EC Number
203-951-1
UN Number
2810
Index Number
603-178-00-3
PubChem CID
8170

Physical-chemical properties

Molecular Formula
C8H18O2
Molar Mass
146.23 g/mol
IUPAC Name
2-hexoxyethanol

Chemical Identifiers

InChI
InChI=1S/C8H18O2/c1-2-3-4-5-7-10-8-6-9/h9H,2-8H2,1H3
InChI Key
UPGSWASWQBLSKZ-UHFFFAOYSA-N

Overview

2-hexoxyethanol (CAS 112-25-4) is a glycol ether solvent with excellent solubility properties and moderate toxicity characteristics. This chemical compound belongs to the family of ethylene glycol ethers, featuring a hexyl group attached to an ethylene glycol backbone. With its molecular formula C8H18O2 and molecular weight of 146.23 g/mol, 2-hexoxyethanol combines the polar characteristics of ethylene glycol with the hydrophobic properties of the hexyl chain, resulting in unique amphiphilic behavior that makes it valuable across multiple industrial applications. The substance presents significant safety considerations, classified under acute toxicity category 4 and skin corrosion category 1B according to CLP regulations. The "Danger" signal word and associated GHS pictograms GHS07 and GHS05 indicate its corrosive nature and potential health hazards upon exposure. Transportation falls under ADR class 6.1, reflecting its toxic properties that require specialized handling protocols during shipping and storage. Key applications include its use as a solvent in coating formulations, particularly in industrial paints and varnishes where its slow evaporation rate and excellent film-forming properties are advantageous. The chemical also serves as an intermediate in cleaning product formulations and as a process solvent in various chemical syntheses. Unlike simpler compounds such as phenylmethanamine, 2-hexoxyethanol offers superior compatibility with both polar and non-polar substances, making it particularly useful in formulations requiring broad solubility ranges. Industrial users appreciate its stability under normal conditions and its ability to enhance the performance characteristics of final products. OYSI maintains reliable supply chains for 2-hexoxyethanol to meet the demanding requirements of European technical markets.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2810
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameEthylenglycolmonohexylether
Marine PollutantNo

Frequently Asked Questions

What is 2-hexoxyethanol?

2-hexoxyethanol is an organic chemical compound with the formula C8H18O2 and CAS number 112-25-4. This glycol ether has a molecular weight of 146.23 g/mol and belongs to the family of alkoxy alcohols. It is classified as a hazardous substance with acute toxicity and skin corrosive properties, requiring careful handling in industrial applications.

What are the physicochemical properties of 2-hexoxyethanol?

2-hexoxyethanol is typically a colorless liquid at room temperature with a characteristic mild odor. As a glycol ether, it exhibits good solubility in both water and organic solvents, making it an effective coupling agent. Its molecular structure (C8H18O2) provides both hydrophilic and lipophilic properties, contributing to its versatility in various formulations.

What is 2-hexoxyethanol used for?

2-hexoxyethanol is primarily used as a solvent in industrial applications, particularly in coatings, paints, and cleaning products. It serves as a coupling agent between water and oil-based components due to its dual solubility properties. Additionally, it finds applications in textile processing, surface treatments, and as an intermediate in chemical synthesis processes.

How to handle 2-hexoxyethanol safely?

2-hexoxyethanol requires careful handling due to its Skin Corr. 1B and Acute Tox. 4 classifications. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or use local exhaust ventilation. Avoid skin and eye contact, and prevent inhalation of vapors. Emergency eyewash and shower facilities should be readily accessible.

How to store 2-hexoxyethanol correctly?

2-hexoxyethanol should be stored in tightly sealed original containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and protected from physical damage. Store separately from incompatible materials such as strong acids, bases, and oxidizing agents. Ensure storage area has appropriate spill containment measures and temperature control.

What to do in case of contact with 2-hexoxyethanol?

Immediate action is required due to the corrosive nature of 2-hexoxyethanol. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, flush immediately with water for 15-20 minutes. If inhaled, move to fresh air. Seek immediate medical attention in all cases of exposure and provide safety data sheet to medical personnel.

How to dispose of 2-hexoxyethanol appropriately?

2-hexoxyethanol must be disposed of as hazardous waste according to local and European regulations. Contact licensed waste disposal companies for proper treatment and disposal. Never discharge into sewers, waterways, or soil. Small quantities should be collected in appropriate containers and labeled clearly. Follow national waste codes and ensure proper documentation for waste tracking and compliance with environmental regulations.

How to transport 2-hexoxyethanol?

2-hexoxyethanol is classified under ADR as Class 6.1 (Toxic substances), Packing Group III, indicating moderate toxicity during transport. Packages must be properly labeled with appropriate hazard labels and meet UN specification requirements. Transport vehicles require appropriate placarding and documentation. Drivers must have ADR certification and carry emergency response information during transit.

Is 2-hexoxyethanol subject to specific regulations?

2-hexoxyethanol is subject to European REACH regulation and must comply with CLP classification requirements. It carries GHS07 and GHS05 pictograms with 'Danger' signal word due to its acute toxicity and corrosive properties. The substance is not currently listed as SVHC under REACH. Users must ensure proper registration, safety data sheet provision, and compliance with occupational exposure limits where established.

Where to buy 2-hexoxyethanol in Europe?

2-hexoxyethanol is available through OYSI, a reliable European distributor of industrial chemicals. OYSI provides quality chemicals with proper documentation, safety data sheets, and regulatory compliance for European markets. As a specialized chemical distributor, OYSI ensures proper handling, packaging, and delivery of hazardous materials like 2-hexoxyethanol to industrial customers across Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.