2-hexoxyethanol

C8H18O2

CAS112-25-4
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
112-25-4
EC Number
203-951-1
UN Number
2810
Index Number
603-178-00-3
PubChem CID
8170

Physical-chemical properties

Molecular Formula
C8H18O2
Molar Mass
146.23 g/mol
IUPAC Name
2-hexoxyethanol

Chemical Identifiers

InChI
InChI=1S/C8H18O2/c1-2-3-4-5-7-10-8-6-9/h9H,2-8H2,1H3
InChI Key
UPGSWASWQBLSKZ-UHFFFAOYSA-N

Overview

2-hexoxyethanol (CAS 112-25-4) is a glycol ether solvent with excellent solvency properties and moderate volatility characteristics. This versatile chemical compound belongs to the glycol ether family and serves as an important industrial solvent in various manufacturing processes. With its molecular formula C8H18O2 and molecular weight of 146.23 g/mol, 2-hexoxyethanol exhibits unique chemical properties that make it valuable for specialized applications requiring controlled evaporation rates and superior dissolving capabilities. The substance is classified under significant safety considerations, bearing GHS pictograms GHS07 and GHS05 with a "Danger" signal word. Its hazard classification includes Acute Toxicity Category 4 and Skin Corrosion Category 1B, necessitating proper handling protocols and protective equipment during industrial use. The ADR classification as Class 6.1 indicates its toxic nature requires specific transportation and storage requirements. In industrial applications, 2-hexoxyethanol primarily functions as a solvent in coating formulations, particularly in high-performance paints and varnishes where controlled drying characteristics are essential. The chemical industry also utilizes this compound in cleaning formulations and as a process solvent in manufacturing operations. Its solvency profile makes it particularly effective for dissolving various organic compounds, though unlike simpler compounds such as phenylmethanamine, it offers more complex solvent characteristics suitable for demanding applications. The compound's moderate volatility and excellent solvency properties distinguish it from other glycol ethers, making it suitable for applications requiring specific evaporation profiles. Safety protocols must always be implemented due to its corrosive and toxic properties. OYSI maintains reliable supply chains for 2-hexoxyethanol to support European industrial customers requiring consistent quality and technical support.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2810
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameEthylenglycolmonohexylether
Marine PollutantNo

Frequently Asked Questions

What is 2-hexoxyethanol?

2-hexoxyethanol is an organic chemical compound with the molecular formula C8H18O2 and CAS number 112-25-4. This glycol ether has a molecular weight of 146.23 g/mol and belongs to the family of alkoxy alcohols. It is classified as a hazardous substance with acute toxicity and skin corrosion properties, requiring careful handling and appropriate safety measures during use.

What are the physicochemical properties of 2-hexoxyethanol?

2-hexoxyethanol is typically a colorless to pale yellow liquid at room temperature with a characteristic mild odor. As a glycol ether, it exhibits good solubility in both water and organic solvents, making it an effective coupling agent. The compound has moderate volatility and viscosity, with its amphiphilic structure providing excellent wetting and penetration properties essential for its various industrial applications.

What is 2-hexoxyethanol used for?

2-hexoxyethanol serves primarily as a solvent and coupling agent in industrial formulations. It is commonly used in coatings, paints, and inks due to its excellent solvent properties and ability to improve flow and leveling. The compound also finds applications in cleaning products, where it acts as a surfactant and solvent, and in textile processing as a wetting agent and dye carrier.

How to handle 2-hexoxyethanol safely?

2-hexoxyethanol must be handled with appropriate personal protective equipment due to its Skin Corr. 1B and Acute Tox. 4 classifications. Workers should wear chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Ensure adequate ventilation to minimize inhalation exposure, and avoid eating, drinking, or smoking in work areas. Always wash hands thoroughly after handling the substance.

How to store 2-hexoxyethanol correctly?

2-hexoxyethanol should be stored in tightly sealed original containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and protected from physical damage. Store separately from incompatible materials such as strong oxidizing agents and acids. Ensure storage areas comply with local fire safety regulations and maintain appropriate temperature controls to prevent degradation.

What to do in case of contact with 2-hexoxyethanol?

Immediate action is required if contact occurs with 2-hexoxyethanol due to its corrosive properties. For skin contact, immediately remove contaminated clothing and rinse affected areas with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water for 15-20 minutes. If inhaled, move to fresh air immediately. Seek immediate medical attention for all exposure incidents.

How to dispose of 2-hexoxyethanol properly?

2-hexoxyethanol waste must be disposed of according to local and national hazardous waste regulations as it is classified under ADR Class 6.1. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of the substance down drains, in soil, or with regular waste. Small quantities may require special collection procedures, while larger amounts need professional hazardous waste management services.

How to transport 2-hexoxyethanol?

2-hexoxyethanol is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. It must be transported in appropriate UN-approved packaging with proper hazard labels and documentation. Vehicles must comply with ADR regulations for toxic substances, including appropriate placarding and driver certification. Ensure packages are secured and protected from damage during transit.

Is 2-hexoxyethanol subject to specific regulations?

2-hexoxyethanol is subject to various European chemical regulations including REACH registration requirements and CLP classification obligations. It is not currently listed as a Substance of Very High Concern (SVHC), but its hazard classification requires compliance with workplace safety regulations and proper risk assessment. Users must follow occupational exposure limits and implement appropriate risk management measures as required by chemical safety legislation.

Where to buy 2-hexoxyethanol in Europe?

2-hexoxyethanol is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI can provide this substance with full regulatory compliance documentation including safety data sheets and certificates of analysis. Contact OYSI directly for availability, packaging options, and delivery throughout Europe, ensuring you receive quality products that meet industry standards and regulatory requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.