Methyl 2-chloroacetate

Methyl 2-chloroacetate is a chlorinated organic ester with the molecular formula C3H5ClO2 and CAS number 96-34-4. This chemical compound has a molecular weight of 108.52 g/mol and belongs to the chloroacetate family. It is classified as a dangerous substance with multiple hazard classes including flammable liquid, acute toxicity, skin irritation, and eye damage. The substance requires careful handling due to its toxic and corrosive properties.

Methyl 2-chloroacetate is typically a colorless to pale yellow liquid at room temperature with a characteristic pungent odor. As an ester compound, it exhibits moderate volatility and is soluble in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The substance has limited water solubility but can hydrolyze in aqueous solutions. Its physical properties make it suitable for various synthetic applications while requiring appropriate ventilation during handling.

Methyl 2-chloroacetate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a key building block for producing various chemicals, including herbicides, pesticides, and pharmaceutical compounds. The substance is also utilized in the synthesis of amino acids, particularly glycine derivatives, and in the production of specialty chemicals. Its reactive chloroacetate group makes it valuable for alkylation reactions in fine chemical synthesis.

Methyl 2-chloroacetate requires strict safety measures due to its acute toxicity and corrosive properties. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure emergency eyewash stations are readily available. Training on proper handling procedures is essential before working with this substance.

Methyl 2-chloroacetate must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points. Use tightly sealed, chemically compatible containers preferably made of glass or appropriate plastic materials. Keep away from strong bases, oxidizing agents, and metals that may cause decomposition. Storage areas should be equipped with appropriate spill containment measures and emergency response equipment. Temperature control is important to prevent degradation and vapor buildup.

Immediate action is required for any contact with methyl 2-chloroacetate due to its corrosive and toxic nature. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. In case of eye contact, flush immediately with large amounts of water and seek medical attention promptly. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Always consult a physician after any exposure incident.

Methyl 2-chloroacetate disposal must comply with local environmental regulations and hazardous waste management requirements. The substance cannot be disposed of through regular waste streams due to its toxic and corrosive properties. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require neutralization or chemical treatment before disposal. Always consult local environmental authorities and maintain proper documentation of waste disposal activities.

Methyl 2-chloroacetate is classified under ADR Class 6.1 (toxic substances), Packing Group I, indicating high toxicity requiring strict transport regulations. Shipments must use UN-approved packaging and proper hazard labeling including GHS pictograms GHS02, GHS06, and GHS05. Transport vehicles require appropriate placarding and emergency response information. Only trained personnel should handle transportation, and shipments must comply with international dangerous goods regulations including proper documentation and emergency procedures.

Methyl 2-chloroacetate is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance carries multiple hazard classifications requiring proper labeling, safety data sheets, and risk assessment documentation. While not currently listed as a SVHC (Substance of Very High Concern), it requires compliance with occupational exposure limits and industrial emission controls. Users must maintain proper chemical inventories and worker safety training records.

Methyl 2-chloroacetate is available through OYSI, a specialized European distributor of technical chemicals and laboratory reagents. OYSI provides reliable supply chains for industrial customers requiring this substance for synthesis and manufacturing applications. As a professional chemical distributor, OYSI ensures proper packaging, documentation, and regulatory compliance for European markets. Contact OYSI directly for availability, specifications, and delivery arrangements to meet your specific requirements for methyl 2-chloroacetate.