(E)-but-2-enal

C4H6O

CAS4170-30-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
4170-30-3
EC Number
224-030-0
UN Number
1143
Index Number
605-009-00-9
PubChem CID
447466

Physical-chemical properties

Molecular Formula
C4H6O
Molar Mass
70.09 g/mol
IUPAC Name
(E)-but-2-enal

Chemical Identifiers

InChI
InChI=1S/C4H6O/c1-2-3-4-5/h2-4H,1H3/b3-2+
InChI Key
MLUCVPSAIODCQM-NSCUHMNNSA-N

Overview

(E)-but-2-enal (CAS 4170-30-3) is an α,β-unsaturated aldehyde with highly reactive properties and significant industrial applications. This organic compound, also known by its IUPAC name (E)-but-2-enal, represents a critical intermediate in various chemical synthesis processes. With the molecular formula C4H6O and a molecular weight of 70.09 g/mol, this aldehyde features a characteristic double bond in the E-configuration between the second and third carbon atoms, contributing to its unique reactivity profile. The compound belongs to the family of unsaturated aldehydes, which are valued for their versatility in organic synthesis and industrial applications. The safety profile of (E)-but-2-enal requires careful consideration, as indicated by its classification under multiple hazard categories including flammable liquid category 2, mutagenicity category 2, and acute toxicity categories 2 and 3. The compound carries the "Danger" signal word and displays multiple GHS pictograms (GHS02, GHS08, GHS06, GHS05, GHS09), reflecting its potential for fire hazards, health effects, and environmental impact. Its ADR classification as class 6.1 underscores the need for specialized handling and transportation protocols. In industrial applications, (E)-but-2-enal serves as a valuable building block in pharmaceutical synthesis, flavor and fragrance production, and as an intermediate in the manufacture of specialty chemicals. Its reactive aldehyde group and conjugated system make it particularly useful in condensation reactions and cycloaddition processes. Unlike more specialized compounds such as 2,2-dibromo-2-cyanoacetamide or 1-chloro-4-isocyanatobenzene, (E)-but-2-enal offers broader synthetic utility across multiple industry sectors. OYSI provides reliable access to high-quality (E)-but-2-enal for European industrial customers, ensuring consistent supply for critical manufacturing processes.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Muta. 2; Acute Tox. 2 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT SE 3; STOT RE 2 *; Sk...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H341

Suspected of causing genetic defects.

H330

Fatal if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H335

May cause respiratory irritation.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H318

Causes serious eye damage.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1143
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameCrotonaldehyd, stabilisiert
Marine PollutantNo

Frequently Asked Questions

What is (E)-but-2-enal?

(E)-but-2-enal is an organic compound with the molecular formula C4H6O and CAS number 4170-30-3. It is an α,β-unsaturated aldehyde with a molecular weight of 70.09 g/mol. This chemical belongs to the aldehyde family and contains a conjugated system with a double bond adjacent to the carbonyl group. It is classified as a highly hazardous substance with multiple health and safety risks including flammability, mutagenicity, and acute toxicity.

What are the physicochemical properties of (E)-but-2-enal?

(E)-but-2-enal is a liquid organic compound at room temperature with characteristic aldehyde properties. As an unsaturated aldehyde, it typically has a pungent, irritating odor. The compound has a molecular weight of 70.09 g/mol and contains both a carbonyl group and a carbon-carbon double bond in trans configuration. Its chemical structure makes it reactive toward nucleophiles and prone to polymerization under certain conditions.

What is (E)-but-2-enal used for?

(E)-but-2-enal is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. It serves as a building block for the production of various chemicals, pharmaceuticals, and specialty compounds. Due to its reactive aldehyde group and conjugated double bond system, it participates in numerous chemical reactions including condensation, addition, and polymerization reactions. Its applications are typically limited to industrial and research settings due to its high toxicity profile.

How to handle (E)-but-2-enal safely?

(E)-but-2-enal requires extreme caution during handling due to its high toxicity and flammability. Personal protective equipment must include chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or under fume hoods. Avoid all sources of ignition as it is classified as Flam. Liq. 2. Prevent skin and eye contact, and avoid inhalation of vapors. Work in controlled environments with emergency procedures in place due to its Acute Tox. 2 and 3 classifications.

How to store (E)-but-2-enal correctly?

(E)-but-2-enal must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers tightly sealed in secondary containment to prevent leaks. Store separately from incompatible materials such as strong oxidizers, bases, and reducing agents. Temperature control is essential to prevent degradation or dangerous reactions. Access should be restricted to trained personnel only, with appropriate fire suppression systems nearby due to its flammable nature.

What to do in case of contact with (E)-but-2-enal?

Immediate action is critical due to the high acute toxicity of (E)-but-2-enal. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and rinse mouth with water. Seek immediate medical attention in all cases of exposure.

How to dispose of (E)-but-2-enal appropriately?

(E)-but-2-enal must be disposed of as hazardous waste according to local and national regulations. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never discharge into drains, soil, or waterways due to environmental risks. Small quantities should be collected in appropriate containers and labeled clearly for hazardous waste pickup. Incineration at authorized facilities may be required. Always consult current waste disposal regulations and safety data sheets before disposal.

How to transport (E)-but-2-enal?

(E)-but-2-enal is classified under ADR as Class 6.1 (toxic substances) Packing Group I, indicating very high danger during transport. Special packaging, labeling, and documentation requirements apply for road transport. Vehicles must display appropriate hazard placards and carry emergency response information. Only trained personnel with proper certifications should handle transportation. Packaging must meet UN specification requirements and be compatible with the chemical to prevent leakage or reactions during transit.

Is (E)-but-2-enal subject to specific regulations?

(E)-but-2-enal is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification for hazard communication. Its Muta. 2 classification places it under strict handling and use restrictions. Although not currently listed as a SVHC, its high toxicity profile means it may face additional regulatory scrutiny. Companies must comply with occupational exposure limits, reporting requirements, and safety data sheet obligations when manufacturing, importing, or using this substance.

Where to buy (E)-but-2-enal in Europe?

(E)-but-2-enal is available through specialized chemical distributors in Europe, including OYSI, which supplies high-quality chemicals to industrial customers across the European market. Due to its hazardous nature and regulatory requirements, purchases typically require proper documentation, safety assessments, and compliance verification. Buyers must demonstrate appropriate handling capabilities and end-use justification. Contact OYSI's technical team for availability, specifications, and regulatory support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.