Ethyl nitrite
C2H5NO2
ethyl nitrite
Consulting for Ethyl nitrite
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Identification
- CAS Number
- 109-95-5
- EC Number
- 203-722-6
- UN Number
- Index Number
- 007-006-00-2
- PubChem CID
- 8026
Physical-chemical properties
- Molecular Formula
- C2H5NO2
- Molar Mass
- 75.07 g/mol
- IUPAC Name
- ethyl nitrite
Chemical Identifiers
- InChI
- InChI=1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3
- InChI Key
- QQZWEECEMNQSTG-UHFFFAOYSA-N
Overview
Ethyl nitrite (CAS 109-95-5) is an organic nitrite compound with vasodilatory properties and high flammability characteristics. Ethyl nitrite represents a significant compound in the nitrite ester family, characterized by its molecular formula C2H5NO2 and molecular weight of 75.07 g/mol. This colorless gas exhibits distinctive chemical properties that make it valuable for specific industrial applications while requiring careful handling due to its hazardous nature. The compound is classified under multiple danger categories including flammable gas, pressurized gas, and acute toxicity, necessitating appropriate safety protocols during storage, transport, and use. The substance demonstrates high volatility and flammability, requiring storage under pressurized conditions and away from ignition sources. Its classification with GHS pictograms GHS02, GHS04, and GHS07 indicates flame, gas under pressure, and health hazard warnings respectively. Unlike simpler compounds such as ethene, ethyl nitrite contains a nitrite functional group that significantly influences its reactivity and biological activity. The compound's acute toxicity classification across multiple exposure routes emphasizes the importance of proper ventilation and personal protective equipment during handling. Industrial applications of ethyl nitrite primarily include its use as an intermediate in organic synthesis and as a precursor for pharmaceutical compounds. The chemical industry utilizes this compound in specialized manufacturing processes where its unique nitrite functionality provides specific reactivity patterns. Additionally, it serves applications in analytical chemistry and research settings where controlled nitrite chemistry is required. OYSI maintains reliable supply chains for ethyl nitrite, ensuring consistent availability for European industrial customers requiring this specialized chemical compound for their technical applications.
Safety & Classification
Flam. Gas 1; Press. Gas; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Frequently Asked Questions
What is ethyl nitrite?
Ethyl nitrite is an organic chemical compound with the molecular formula C2H5NO2 and CAS number 109-95-5. It belongs to the nitrite ester family and has a molecular weight of 75.07 g/mol. This compound is classified as a flammable and pressurized gas with acute toxicity properties, making it a hazardous substance requiring careful handling and storage procedures in industrial applications.
What are the physicochemical properties of ethyl nitrite?
Ethyl nitrite is a colorless gas at room temperature with a characteristic sweet, fruity odor. As indicated by its classification as a pressurized gas, it exists in gaseous form under normal conditions but can be liquefied under pressure. The compound has limited solubility in water but dissolves readily in organic solvents such as ethanol and ether, typical of nitrite esters.
What is ethyl nitrite used for?
Ethyl nitrite is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a nitrosating agent in various chemical reactions and can be used in the production of other organic compounds. Additionally, it has applications in analytical chemistry as a reagent and historically has been used in medical applications, though its use is now highly regulated due to safety concerns.
How to handle ethyl nitrite safely?
Ethyl nitrite requires strict safety protocols due to its flammable and toxic nature. Personnel must wear appropriate personal protective equipment including gas-tight chemical suits, respiratory protection, and safety goggles. Work should be conducted in well-ventilated areas or under fume hoods, away from ignition sources. Emergency safety equipment including eyewash stations and safety showers must be readily accessible during handling operations.
How to store ethyl nitrite correctly?
Ethyl nitrite must be stored in pressure-rated containers in cool, well-ventilated areas away from heat sources and ignition points. Storage areas should be equipped with appropriate ventilation systems and gas detection equipment. The compound should be kept away from incompatible materials such as strong oxidizers and reducing agents. Storage facilities must comply with local regulations for flammable and pressurized gases.
What to do in case of contact with ethyl nitrite?
Ethyl nitrite exposure requires immediate medical attention due to its acute toxicity. In case of inhalation, move the person to fresh air immediately and provide oxygen if breathing is difficult. For skin contact, remove contaminated clothing and rinse with plenty of water. If ingested, do not induce vomiting and seek immediate medical care. Always contact emergency services and provide the safety data sheet to medical personnel.
How to dispose of ethyl nitrite appropriately?
Ethyl nitrite disposal must comply with local and national hazardous waste regulations due to its classification as dangerous goods. The substance should never be released into the environment or disposed of through regular waste streams. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may require special neutralization procedures before disposal, always following regulatory guidelines.
How to transport ethyl nitrite?
Ethyl nitrite transport requires compliance with dangerous goods regulations as it is classified as a flammable and pressurized gas. Specialized pressure vessels and appropriate packaging materials must be used. Transportation vehicles must be properly placarded and drivers must hold relevant dangerous goods certifications. Shipping documentation must include proper hazard classifications and emergency response information.
Is ethyl nitrite subject to specific regulations?
Ethyl nitrite is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification regulations. Its acute toxicity and flammable gas properties mandate compliance with workplace safety standards and environmental protection laws. The compound is not listed as an SVHC substance but requires proper notification and documentation for commercial use and distribution throughout the supply chain.
Where to buy ethyl nitrite in Europe?
Ethyl nitrite is available through specialized chemical distributors in Europe, including OYSI, which supplies high-quality chemical products to industrial customers. Due to its hazardous classification, purchases typically require proper documentation, safety certifications, and compliance with regulatory requirements. Buyers must demonstrate appropriate handling capabilities and storage facilities before procurement from authorized distributors.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.