Chloro(methoxy)methane

C2H5ClO

chloro(methoxy)methane

CAS107-30-2
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
107-30-2
EC Number
203-480-1
UN Number
1239
Index Number
603-075-00-3
PubChem CID
7864

Physical-chemical properties

Molecular Formula
C2H5ClO
Molar Mass
80.51 g/mol
IUPAC Name
chloro(methoxy)methane

Chemical Identifiers

InChI
InChI=1S/C2H5ClO/c1-4-2-3/h2H2,1H3
InChI Key
XJUZRXYOEPSWMB-UHFFFAOYSA-N

Overview

Chloro(methoxy)methane (CAS 107-30-2) is an organochlorine compound with high volatility and significant toxicological properties. This versatile chemical intermediate, also known by its molecular formula C2H5ClO, represents an important class of halogenated ethers widely utilized in industrial synthesis processes. With a molecular weight of 80.51 g/mol, chloro(methoxy)methane exhibits characteristics typical of low molecular weight organochlorine compounds, including high vapor pressure and lipophilic properties that influence both its industrial utility and safety considerations. The compound is classified under multiple hazard categories, including Category 1A carcinogen and Category 2 flammable liquid, necessitating stringent handling protocols and specialized storage conditions. Its GHS classification encompasses fire hazard (GHS02), health hazard (GHS08), and acute toxicity (GHS07) pictograms, reflecting the comprehensive safety measures required during transport and use. The ADR Class 6.1 designation further emphasizes its toxic nature, requiring specialized logistics management. Industrially, chloro(methoxy)methane serves primarily as a chemical intermediate in pharmaceutical synthesis, particularly in the production of methylating agents and specialized organic compounds. It also finds application in research laboratories for specific organic transformations and as a reagent in fine chemical manufacturing. Unlike structurally different compounds such as 2-(chloromethyl)oxirane, chloro(methoxy)methane offers unique reactivity patterns due to its methoxy functionality. The compound requires careful handling protocols similar to other toxic organochlorine substances, with particular attention to its carcinogenic classification and flammability characteristics. OYSI maintains availability of chloro(methoxy)methane with full technical documentation and regulatory compliance support for qualified industrial customers.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 1A; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H350

May cause cancer.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1239
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameMethylchlormethylether
Marine PollutantNo

Frequently Asked Questions

What is chloro(methoxy)methane?

Chloro(methoxy)methane is an organochlorine compound with the molecular formula C2H5ClO and CAS number 107-30-2. This chemical substance has a molecular weight of 80.51 g/mol and belongs to the category of chlorinated ethers. It is classified as a highly hazardous substance due to its carcinogenic properties (Category 1A) and flammable nature. The compound requires careful handling and is subject to strict safety regulations due to its significant health and fire risks.

What are the physicochemical properties of chloro(methoxy)methane?

Chloro(methoxy)methane is a volatile organic liquid at room temperature with characteristic ether-like properties. As a chlorinated ether compound, it typically exhibits good solubility in organic solvents while having limited water solubility. The substance is highly flammable, classified as Flammable Liquid Category 2, meaning it has a flash point below 23°C. Its relatively low molecular weight of 80.51 g/mol contributes to its volatile nature and potential for vapor formation.

What is chloro(methoxy)methane used for?

Chloro(methoxy)methane serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. Due to its reactive chlorine and methoxy functional groups, it is utilized in the production of various organic compounds through substitution and coupling reactions. The substance may also find applications in specialized chemical processes requiring chlorinated ether compounds. However, its use is heavily restricted due to its carcinogenic classification, limiting applications to controlled industrial environments with appropriate safety measures.

How to handle chloro(methoxy)methane safely?

Chloro(methoxy)methane requires extreme caution during handling due to its carcinogenic and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection to prevent inhalation exposure. Work must be conducted in well-ventilated areas or under fume hoods to minimize vapor exposure. Due to its flammable nature, eliminate all ignition sources and use explosion-proof equipment. Only trained personnel should handle this substance, following strict occupational hygiene protocols.

How to store chloro(methoxy)methane correctly?

Chloro(methoxy)methane must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources, sparks, and open flames. Storage areas should be equipped with appropriate fire suppression systems and maintained below 25°C. The substance should be segregated from incompatible materials such as strong oxidizers, acids, and bases. Secondary containment is recommended to prevent environmental release. Access should be restricted to authorized personnel only, with proper inventory tracking due to its hazardous classification.

What to do in case of contact with chloro(methoxy)methane?

Immediate action is required following exposure to chloro(methoxy)methane due to its toxic properties. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move the person to fresh air immediately and seek medical attention. For ingestion, do not induce vomiting and seek immediate medical care. Always consult a poison control center or medical professional.

How to dispose of chloro(methoxy)methane appropriately?

Chloro(methoxy)methane requires disposal as hazardous waste through licensed waste management facilities specializing in carcinogenic substances. Due to its Category 1A carcinogenic classification, it cannot be disposed of through normal waste streams. Incineration at high temperatures in approved hazardous waste facilities is typically the preferred method. All disposal activities must comply with local environmental regulations and waste classification codes. Maintain detailed disposal records and use only certified waste contractors with appropriate permits for carcinogenic materials.

How to transport chloro(methoxy)methane?

Chloro(methoxy)methane is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating high toxicity requiring stringent transport conditions. Transportation must comply with dangerous goods regulations using appropriate UN-specification packaging designed for toxic liquids. Vehicles must display proper hazard placards and carry emergency response information. Only certified dangerous goods drivers can transport this substance, and shipments require proper documentation including safety data sheets. Emergency response equipment must be available during transport.

Is chloro(methoxy)methane subject to specific regulations?

Chloro(methoxy)methane is subject to extensive regulatory oversight under multiple frameworks including REACH, CLP, and national chemical safety legislation. Its Category 1A carcinogenic classification triggers strict workplace exposure limits and mandatory risk assessments. The substance requires authorization or restriction under REACH due to its hazardous properties. Manufacturing, importation, and use are heavily regulated, requiring compliance with occupational safety directives and environmental protection laws. Users must maintain detailed exposure records and implement appropriate risk management measures.

Where to buy chloro(methoxy)methane in Europe?

Chloro(methoxy)methane is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. Due to the compound's carcinogenic classification and regulatory restrictions, procurement requires verification of legitimate industrial use and appropriate safety infrastructure. OYSI ensures full regulatory compliance, proper documentation, and safe packaging for transportation. Customers must demonstrate adequate handling capabilities and regulatory compliance before purchase approval, as this substance is restricted to qualified industrial users only.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.