Chloro(methoxy)methane
C2H5ClO
chloro(methoxy)methane
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Identification
- CAS Number
- 107-30-2
- EC Number
- 203-480-1
- UN Number
- 1239
- Index Number
- 603-075-00-3
- PubChem CID
- 7864
Physical-chemical properties
- Molecular Formula
- C2H5ClO
- Molar Mass
- 80.51 g/mol
- IUPAC Name
- chloro(methoxy)methane
Chemical Identifiers
- InChI
- InChI=1S/C2H5ClO/c1-4-2-3/h2H2,1H3
- InChI Key
- XJUZRXYOEPSWMB-UHFFFAOYSA-N
Overview
Chloro(methoxy)methane (CAS 107-30-2) is an organohalogen compound with highly flammable properties and significant toxicological concerns requiring specialized handling protocols. This volatile organic compound, also known by its IUPAC designation chloro(methoxy)methane, represents a critical chemical intermediate in industrial synthesis applications. With the molecular formula C2H5ClO and a molecular weight of 80.51 g/mol, this substance exhibits dual functional groups that make it particularly reactive in organic chemistry processes. The compound is classified under multiple hazard categories including Flammable Liquid Category 2 and Carcinogen Category 1A, necessitating stringent safety measures during storage, handling, and transportation. The substance's hazard profile is reflected in its GHS pictograms including flame (GHS02), health hazard (GHS08), and exclamation mark (GHS07) symbols, with the signal word "Danger" emphasizing the severity of associated risks. Its ADR classification as Class 6.1 further underscores the toxic nature of this material during transport operations. The acute toxicity ratings across multiple exposure routes demand comprehensive personal protective equipment and engineered controls in workplace environments. Industrial applications of chloro(methoxy)methane primarily focus on its role as a methylating agent in pharmaceutical synthesis and as an intermediate in the production of specialized organic compounds. The chemical industry also utilizes this substance in certain polymer modification processes, though its use is increasingly regulated due to carcinogenic properties. Unlike structurally different compounds such as 2-(chloromethyl)oxirane, which serves in epoxy applications, chloro(methoxy)methane's specific reactivity profile makes it valuable for targeted synthetic transformations. OYSI provides chloro(methoxy)methane to qualified industrial customers with comprehensive documentation supporting safe handling and regulatory compliance throughout European markets.
Safety & Classification
Flam. Liq. 2; Carc. 1A; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1239 |
| ADR Class | 6.1 |
| Packing Group | I |
| Tunnel Code | C/D |
| Proper Shipping Name | Methylchlormethylether |
| Marine Pollutant | No |
Frequently Asked Questions
What is chloro(methoxy)methane?
Chloro(methoxy)methane is an organochlorine compound with the molecular formula C2H5ClO and CAS number 107-30-2. This chemical substance has a molecular weight of 80.51 g/mol and belongs to the class of chlorinated ethers. It is classified as a Category 1A carcinogen and flammable liquid, making it a highly hazardous substance requiring strict handling protocols in industrial applications.
What are the physicochemical properties of chloro(methoxy)methane?
Chloro(methoxy)methane is a volatile organic compound that typically exists as a colorless liquid at room temperature. As a chlorinated ether, it exhibits moderate polarity and is likely miscible with organic solvents. The compound has a relatively low molecular weight of 80.51 g/mol, contributing to its volatile nature and flammable characteristics classified under Flam. Liq. 2 category.
What is chloro(methoxy)methane used for?
Chloro(methoxy)methane serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. Its reactive chloro and methoxy functional groups make it valuable for creating more complex molecular structures. However, due to its Category 1A carcinogenic classification, its use is heavily restricted and limited to specialized industrial processes with stringent safety controls and regulatory oversight.
How to handle chloro(methoxy)methane safely?
Safe handling of chloro(methoxy)methane requires comprehensive personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection due to its carcinogenic and toxic properties. Work must be conducted in well-ventilated areas or fume hoods to prevent inhalation exposure. All handling procedures should follow strict protocols given its Acute Tox. 4 classification and flammable nature.
How to store chloro(methoxy)methane correctly?
Proper storage of chloro(methoxy)methane requires cool, dry, well-ventilated areas away from heat sources and ignition points due to its Flam. Liq. 2 classification. Containers must be tightly sealed and stored in secondary containment systems. The storage area should be equipped with appropriate fire suppression systems and emergency response equipment, with access restricted to authorized personnel only.
What to do in case of contact with chloro(methoxy)methane?
Immediate emergency response for chloro(methoxy)methane exposure includes removing contaminated clothing and flushing affected skin or eyes with copious amounts of water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention. Given its carcinogenic properties and acute toxicity, all exposures require prompt medical evaluation and monitoring by qualified healthcare professionals.
How to dispose of chloro(methoxy)methane appropriately?
Disposal of chloro(methoxy)methane must be conducted through licensed hazardous waste disposal facilities due to its carcinogenic classification and environmental hazards. The substance cannot be disposed of in regular waste streams or sewage systems. All disposal activities must comply with local, national, and EU waste regulations, requiring proper documentation and tracking throughout the disposal process.
How to transport chloro(methoxy)methane?
Transportation of chloro(methoxy)methane falls under ADR Class 6.1 (toxic substances) Packing Group I, indicating high danger level. Vehicles must carry appropriate hazard placards and emergency response information. Drivers require specialized training for hazardous materials transport, and shipments must use UN-approved packaging. All transport documentation must comply with international dangerous goods regulations for road transport.
Is chloro(methoxy)methane subject to specific regulations?
Chloro(methoxy)methane is subject to stringent regulations under EU REACH and CLP regulations due to its Category 1A carcinogenic classification. Its use is heavily restricted and requires authorization for specific applications. Companies handling this substance must comply with occupational exposure limits, worker protection requirements, and reporting obligations. Special permits may be required for import, use, and distribution activities.
Where to buy chloro(methoxy)methane in Europe?
Chloro(methoxy)methane is available through specialized chemical distributors like OYSI, which serves the European market with technical-grade chemicals. Due to its highly regulated status and carcinogenic properties, procurement requires proper licensing, safety documentation, and compliance with REACH regulations. Buyers must demonstrate legitimate industrial use and appropriate safety management systems before purchase authorization.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.