Butan-1-amine

Butan-1-amine is a primary aliphatic amine with the molecular formula C4H11N and CAS number 109-73-9. It consists of a four-carbon chain with an amino group (-NH2) attached to the terminal carbon. With a molecular weight of 73.14 g/mol, this colorless liquid belongs to the class of short-chain primary amines and exhibits typical basic properties due to its amino functional group.

Butan-1-amine is a colorless liquid with a strong ammonia-like odor characteristic of primary amines. It has a boiling point of approximately 78°C and is highly soluble in water due to hydrogen bonding between the amino group and water molecules. The compound is also miscible with most organic solvents and exhibits basic properties with a pKa around 10.6, making it a moderately strong base.

Butan-1-amine serves as an important intermediate in pharmaceutical synthesis, particularly for producing active pharmaceutical ingredients and drug precursors. It is used in the manufacture of pesticides, rubber chemicals, and corrosion inhibitors. The compound also finds applications in the production of surfactants, dyes, and as a building block for various organic synthesis reactions in fine chemical manufacturing.

Butan-1-amine requires careful handling due to its corrosive nature and flammability. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from ignition sources, heat, and sparks. Use explosion-proof electrical equipment and ensure proper grounding of containers during transfer operations.

Butan-1-amine must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points due to its flammable nature. Use tightly sealed containers made of compatible materials and keep away from acids, oxidizing agents, and strong electrophiles. Storage temperature should remain below 25°C, and containers should be grounded to prevent static electricity buildup during handling.

Butan-1-amine contact requires immediate action due to its corrosive properties. For skin contact, immediately flush with large amounts of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse thoroughly with water and seek medical attention immediately. If inhaled, move to fresh air and seek medical help. Never induce vomiting if ingested; rinse mouth and seek immediate medical attention.

Butan-1-amine disposal must comply with local and national hazardous waste regulations as it is classified as corrosive and flammable waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never pour down drains or release into the environment. Small quantities may be neutralized carefully with dilute acids under controlled conditions by trained personnel, followed by appropriate wastewater treatment.

Butan-1-amine is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations. Packages must meet UN specification standards and be properly labeled with appropriate hazard labels and markings. Transport vehicles must be equipped with appropriate safety equipment and drivers must hold ADR certification. Segregation from incompatible materials and proper documentation are mandatory for legal transport.

Butan-1-amine is subject to various European regulations including REACH registration requirements and CLP classification as a hazardous substance. It is not currently listed as an SVHC (Substance of Very High Concern). Companies must comply with safety data sheet requirements, workplace exposure limits, and proper labeling according to GHS standards. Industrial users may need permits depending on quantities and local regulations.

Butan-1-amine is available through OYSI, a trusted European distributor of technical chemicals serving various industries across Europe. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. As a specialized chemical distributor, OYSI ensures reliable supply chains and technical expertise to support your industrial applications and research needs.