Ethyl (E)-4-oxo-4-phenylbut-2-enoate

Ethyl (E)-4-oxo-4-phenylbut-2-enoate is an organic chemical compound with the molecular formula C12H12O3 and CAS number 15121-89-8. This substance has a molecular weight of 204.22 g/mol and belongs to the class of aromatic ketone esters. It features a phenyl group attached to a butenoate structure with specific E-configuration stereochemistry, making it valuable for various synthetic applications in organic chemistry.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate is an organic ester compound with a molecular weight of 204.22 g/mol and formula C12H12O3. As an aromatic ketone ester, it typically exists as a solid or liquid at room temperature depending on purity and conditions. The compound contains both hydrophobic aromatic components and polar ester functionalities, affecting its solubility characteristics in various solvents.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate serves as an important intermediate in organic synthesis and pharmaceutical chemistry. This compound is primarily utilized in the development of active pharmaceutical ingredients, fine chemicals, and specialized organic compounds. Its unique structure with both aromatic and ester functionalities makes it valuable for creating complex molecular frameworks in research and industrial applications.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Dam. 1, and Skin Sens. 1. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin and eye contact, and ensure immediate access to eyewash stations and safety showers.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate should be stored in tightly sealed, chemically compatible containers in a cool, dry, and well-ventilated area. Keep away from heat sources, direct sunlight, and incompatible materials. Due to its hazard classification including eye damage and skin irritation potential, ensure secure storage away from unauthorized access and maintain proper labeling with GHS pictograms GHS07, GHS05, and GHS09.

Immediate action is required if contact occurs with ethyl (E)-4-oxo-4-phenylbut-2-enoate due to its eye damage and skin irritation classification. For eye contact, flush immediately with plenty of water for at least 15 minutes and seek medical attention. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air. Remove contaminated clothing and seek medical advice if irritation persists or symptoms develop.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate must be disposed of according to local and national hazardous waste regulations due to its toxicity classification and environmental hazard designation (Aquatic Acute 1). Contact licensed waste disposal companies specialized in hazardous chemical waste. Never dispose of this substance through regular waste streams, sewage systems, or soil. Ensure proper documentation and compliance with waste tracking requirements in your jurisdiction.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. This classification requires appropriate hazardous material packaging, labeling, and documentation during transport. Drivers must have proper hazmat certification, and vehicles must display appropriate placards. Ensure compliance with international dangerous goods regulations including proper shipping names, UN numbers, and emergency response information.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate is regulated under European CLP regulation with specific hazard classifications and labeling requirements including GHS pictograms. The substance is not currently listed as a SVHC under REACH regulation. However, its toxic and environmentally hazardous properties require compliance with workplace safety regulations, environmental protection laws, and proper hazard communication throughout the supply chain including safety data sheet provisions.

Ethyl (E)-4-oxo-4-phenylbut-2-enoate is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical supplier, OYSI ensures quality standards and proper handling procedures for laboratory and industrial customers across Europe requiring this specialized organic compound.