4-chloro-3-methylphenol
C7H7ClO
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Identification
- CAS Number
- 59-50-7
- EC Number
- 200-431-6
- UN Number
- 3437
- Index Number
- 604-014-00-3
- PubChem CID
- 1732
Physical-chemical properties
- Molecular Formula
- C7H7ClO
- Molar Mass
- 142.58 g/mol
- IUPAC Name
- 4-chloro-3-methylphenol
Chemical Identifiers
- InChI
- InChI=1S/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3
- InChI Key
- CFKMVGJGLGKFKI-UHFFFAOYSA-N
Overview
4-chloro-3-methylphenol (CAS 59-50-7) is a chlorinated phenolic compound with antimicrobial properties and industrial antiseptic applications. This halogenated phenol derivative represents an important class of industrial chemicals widely utilized across various sectors for its biocidal and preservative characteristics. The compound features a benzene ring substituted with both chlorine and methyl groups alongside a hydroxyl functional group, contributing to its distinctive chemical behavior and biological activity. With the molecular formula C7H7ClO and a molecular mass of 142.58 g/mol, 4-chloro-3-methylphenol exhibits enhanced stability and efficacy compared to unsubstituted phenols. The substance is classified under multiple hazard categories, including acute toxicity (Category 4), skin corrosion (Category 1C), and aquatic toxicity, requiring careful handling protocols and appropriate safety measures during storage, transportation, and application. Its ADR classification as Class 6.1 emphasizes the need for specialized logistics considerations. The compound shares structural similarities with other chlorinated aromatics, though it differs significantly from quaternary phosphonium salts like methyl(triphenyl)phosphanium chloride in terms of mechanism of action and application scope. Primary industrial applications include formulation of disinfectants, wood preservatives, and antimicrobial agents for various industrial processes. The compound also serves as an intermediate in pharmaceutical synthesis and specialty chemical manufacturing. Its effectiveness against a broad spectrum of microorganisms makes it valuable in industries requiring stringent hygiene standards. OYSI maintains reliable supply chains for 4-chloro-3-methylphenol, ensuring consistent availability for European industrial customers requiring high-quality chemical intermediates and specialty compounds.
Safety & Classification
Acute Tox. 4; STOT SE 3; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1B; Aquatic Acute 1; Aquatic Chron...
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Harmful if swallowed.
May cause respiratory irritation.
Causes severe skin burns and eye damage.
Causes serious eye damage.
May cause an allergic skin reaction.
Very toxic to aquatic life.
Harmful to aquatic life with long lasting effects.
Very toxic to aquatic life with long lasting effects.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3437 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | 4-Chlor-m-cresol, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is 4-chloro-3-methylphenol?
4-chloro-3-methylphenol is an organochlorine compound with the molecular formula C7H7ClO and CAS number 59-50-7. This chemical substance belongs to the phenol family and features both chlorine and methyl substituents on the benzene ring. With a molecular weight of 142.58 g/mol, it is classified as a hazardous substance requiring careful handling due to its toxic, corrosive, and sensitizing properties.
What are the physicochemical properties of 4-chloro-3-methylphenol?
4-chloro-3-methylphenol is typically a solid crystalline substance at room temperature with a characteristic phenolic odor. As a phenolic compound, it exhibits moderate solubility in water and good solubility in organic solvents such as alcohols and ethers. The presence of both chlorine and methyl groups affects its volatility and stability compared to unsubstituted phenol.
What is 4-chloro-3-methylphenol used for?
4-chloro-3-methylphenol is primarily used as an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic chemicals. It serves as a building block in the production of antimicrobial agents and preservatives. The compound is also utilized in research and development applications within the chemical industry for creating specialized chemical products and formulations.
How to handle 4-chloro-3-methylphenol safely?
4-chloro-3-methylphenol requires strict safety measures including wearing appropriate personal protective equipment: chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Due to its corrosive nature (Skin Corr. 1C) and sensitizing properties (Skin Sens. 1B), prevent all skin and eye contact. Ensure emergency shower and eyewash stations are accessible.
How to store 4-chloro-3-methylphenol correctly?
4-chloro-3-methylphenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers in secondary containment to prevent spills. Store separately from incompatible materials such as strong oxidizers and bases. Ensure storage areas are equipped with appropriate spill control measures and maintain proper inventory records.
What to do in case of contact with 4-chloro-3-methylphenol?
Skin contact with 4-chloro-3-methylphenol requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Contact poison control if necessary.
How to dispose of 4-chloro-3-methylphenol appropriately?
4-chloro-3-methylphenol must be disposed of as hazardous waste through licensed waste management companies in accordance with local and European regulations. Due to its aquatic toxicity classification (Aquatic Acute 1), prevent environmental release. Contaminated packaging should also be treated as hazardous waste. Never dispose of this substance down drains or in regular waste streams.
How to transport 4-chloro-3-methylphenol?
4-chloro-3-methylphenol is classified under ADR as Class 6.1 (toxic substances), Packing Group II, requiring specialized packaging and documentation for transport. Shipments must comply with dangerous goods regulations including proper labeling with GHS pictogrammes (GHS05, GHS07, GHS09) and hazard warnings. Only authorized carriers experienced in handling toxic chemicals should transport this substance.
Is 4-chloro-3-methylphenol subject to specific regulations?
4-chloro-3-methylphenol is subject to REACH registration requirements and CLP classification regulations in Europe. While not currently listed as an SVHC (Substance of Very High Concern), it requires safety data sheets and proper hazard communication due to its multiple hazard classifications including acute toxicity, skin corrosion, and environmental hazards. Compliance with occupational exposure limits may apply.
Where to buy 4-chloro-3-methylphenol in Europe?
4-chloro-3-methylphenol is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides this substance with proper documentation including safety data sheets and certificates of analysis. Contact OYSI directly for availability, packaging options, and technical support to ensure compliance with your specific application requirements and regulatory obligations.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.