4-chloro-3-methylphenol

4-chloro-3-methylphenol is an organochlorine compound with the molecular formula C7H7ClO and CAS number 59-50-7. This chemical belongs to the phenol family and has a molecular weight of 142.58 g/mol. It is characterized by a benzene ring substituted with a hydroxyl group, a chlorine atom at the 4-position, and a methyl group at the 3-position, making it a halogenated phenolic derivative with specific chemical properties.

4-chloro-3-methylphenol is typically a crystalline solid at room temperature with a characteristic phenolic odor. As a chlorinated phenol derivative, it exhibits moderate solubility in water and good solubility in organic solvents like alcohols and ethers. The presence of both the hydroxyl group and chlorine substituent influences its polarity and reactivity. Its molecular structure contributes to its stability under normal conditions while maintaining reactivity typical of phenolic compounds.

4-chloro-3-methylphenol is primarily used as an intermediate in chemical synthesis and pharmaceutical manufacturing. It serves as a building block for producing various organic compounds, including dyes, pharmaceuticals, and specialty chemicals. The compound finds applications in research and development activities, particularly in the synthesis of more complex molecules. Its phenolic structure makes it valuable for creating derivatives with enhanced biological or chemical properties for industrial applications.

4-chloro-3-methylphenol requires careful handling due to its classification as Danger with multiple hazard classes. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or use fume hoods to avoid inhalation. The compound is corrosive to skin and eyes, toxic if swallowed, and may cause skin sensitization, requiring strict adherence to safety protocols during handling.

4-chloro-3-methylphenol should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and in original packaging to prevent contamination and moisture absorption. Store away from strong bases, oxidizing agents, and reactive metals. Ensure storage areas are equipped with appropriate spill containment measures and maintain temperature control to prevent decomposition or unwanted reactions.

Immediate action is crucial due to the corrosive nature of 4-chloro-3-methylphenol. For skin contact, remove contaminated clothing and rinse affected area with copious amounts of water for at least 15 minutes. For eye contact, flush immediately with water for 15-20 minutes and remove contact lenses if present. If swallowed, do not induce vomiting and seek immediate medical attention. For inhalation, move to fresh air immediately and seek medical help if symptoms persist.

4-chloro-3-methylphenol must be disposed of as hazardous waste according to local and European regulations due to its toxic and environmental hazard classifications. The compound requires specialized treatment at authorized waste disposal facilities equipped to handle chlorinated organic compounds. Never dispose of down drains or in regular waste. Contact licensed waste management companies for proper collection and disposal, ensuring compliance with ADR transport requirements during waste removal.

4-chloro-3-methylphenol is classified under ADR Class 6.1 (Toxic substances) Packing Group II, indicating moderate toxicity requiring specific transport precautions. Packaging must comply with UN specifications for dangerous goods, using appropriate containers that prevent leakage and contamination. Transport vehicles must display proper hazard placards and carry emergency response information. Only trained personnel should handle the transport, and proper documentation including safety data sheets must accompany shipments.

4-chloro-3-methylphenol is regulated under European REACH and CLP regulations due to its hazardous properties, though it is not currently listed as a Substance of Very High Concern (SVHC). The compound must comply with classification and labeling requirements showing GHS pictograms GHS05, GHS07, and GHS09. Users must follow occupational exposure limits and implement appropriate risk management measures. Registration requirements may apply depending on import/manufacturing volumes and intended uses.

4-chloro-3-methylphenol is available through OYSI, a trusted European distributor of specialty chemicals serving industrial and research customers across Europe. OYSI provides quality-assured products with complete documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures compliance with European regulations and offers reliable supply chain management for customers requiring this specialized phenolic compound for their industrial or research applications.