4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline;hydrochloride

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride is a halogenated aromatic amine compound with CAS number 113674-95-6. This chemical features a complex molecular structure containing chlorine, fluorine, and trifluoromethyl groups attached to a phenoxy-aniline backbone. With a molecular formula of C13H9Cl2F4NO and molecular weight of 342.11 g/mol, it belongs to the class of substituted anilines commonly used in pharmaceutical and chemical synthesis applications.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride is a solid compound at room temperature with a molecular weight of 342.11 g/mol. The presence of multiple halogen substituents (chlorine and fluorine atoms) and the trifluoromethyl group significantly influences its chemical stability and solubility characteristics. As a hydrochloride salt, it typically exhibits enhanced water solubility compared to its free base form, making it more suitable for various chemical processes and applications.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride is primarily used as an intermediate in pharmaceutical synthesis and chemical manufacturing. Its unique halogenated structure makes it valuable for developing agrochemicals, specialty chemicals, and pharmaceutical compounds. The compound serves as a building block in organic synthesis reactions, particularly in the production of more complex molecules where the specific arrangement of fluorine, chlorine, and trifluoromethyl groups provides desired chemical and biological properties.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride requires careful handling due to its classification as Acute Tox. 4, Eye Dam. 1, and Skin Sens. 1. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or use local exhaust ventilation to minimize inhalation exposure. Avoid generating dust and ensure proper hygiene practices including thorough hand washing after handling.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protected from moisture, heat, and direct sunlight. Due to its aquatic toxicity classification (Aquatic Acute 1, Aquatic Chronic 1), ensure storage areas are designed to prevent environmental release. Store separately from strong oxidizing agents, acids, and bases. Maintain appropriate temperature conditions to preserve chemical stability and prevent decomposition.

In case of skin contact with 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek immediate medical attention due to its Eye Dam. 1 classification. If inhaled, move to fresh air immediately. In all cases of exposure, seek medical advice promptly and provide the safety data sheet to medical personnel.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride must be disposed of as hazardous waste according to local, national, and EU regulations. Due to its aquatic toxicity (Aquatic Acute 1, Aquatic Chronic 1), prevent release to water bodies, soil, or atmosphere. Contact licensed waste disposal companies specialized in handling toxic chemicals. Incineration at high temperatures in approved facilities is typically the recommended disposal method. Never dispose of this substance through regular waste streams or pour down drains.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride is classified as ADR Class 6.1 (toxic substances), Packing Group III for transportation. It requires appropriate hazardous goods packaging, labeling, and documentation according to ADR regulations. Vehicles must display proper hazard placards and carry emergency response information. Only trained personnel should handle the transportation, and drivers must possess appropriate hazardous materials certifications. Ensure packages are properly secured and protected from damage during transit.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride is subject to REACH regulation requiring registration for manufacture or import above one tonne per year. It must comply with CLP regulation for classification, labeling, and packaging with GHS pictograms (GHS05, GHS07, GHS08, GHS09) and danger signal word. While not currently listed as SVHC, its multiple hazard classifications require strict compliance with occupational safety regulations and environmental protection measures throughout the supply chain.

4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline hydrochloride is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with proper regulatory documentation, safety data sheets, and certificates of analysis. As a professional chemical supplier, OYSI ensures compliance with European regulations including REACH registration requirements and proper hazardous goods handling. Contact OYSI directly for availability, specifications, and pricing information for your specific application requirements.