Ethoxyethane

C4H10O

ethoxyethane

CAS60-29-7
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
60-29-7
EC Number
200-467-2
UN Number
1155
Index Number
603-022-00-4
PubChem CID
3283

Physical-chemical properties

Molecular Formula
C4H10O
Molar Mass
74.12 g/mol
IUPAC Name
ethoxyethane

Chemical Identifiers

InChI
InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3
InChI Key
RTZKZFJDLAIYFH-UHFFFAOYSA-N

Overview

Ethoxyethane (CAS 60-29-7) is a highly flammable ether solvent with excellent dissolving properties and low boiling point characteristics. Ethoxyethane, commonly known as diethyl ether, represents one of the most important ether compounds in industrial chemistry. This colorless, volatile organic solvent with the molecular formula C4H10O exhibits exceptional solvent properties that have made it indispensable across numerous technical applications. With its characteristic sweet, pungent odor and molecular weight of 74.12 g/mol, ethoxyethane demonstrates unique physical and chemical properties that distinguish it from other organic solvents. The compound's classification as Flammable Liquid Category 1 under GHS regulations reflects its extremely low flash point and high vapor pressure, requiring stringent safety measures during handling and storage. Its acute toxicity classification (Category 4) and specific target organ toxicity designation emphasize the importance of proper ventilation and personal protective equipment in occupational settings. The ADR Class 3 classification governs its transportation requirements as a dangerous good. Industrial applications of ethoxyethane span multiple sectors, including its use as an extraction solvent in pharmaceutical manufacturing, where its selective dissolving properties prove invaluable for isolating organic compounds. The chemical industry utilizes ethoxyethane as a reaction medium and starting material for various synthetic processes. Unlike aromatic solvents such as ethylbenzene, ethoxyethane offers unique advantages in applications requiring rapid evaporation and minimal residue formation. The compound's versatility extends to laboratory applications, where its anhydrous properties and chemical inertness make it suitable for sensitive reactions requiring moisture-free conditions. Quality control and proper storage are essential due to its tendency to form explosive peroxides upon prolonged exposure to air and light. OYSI maintains reliable supply chains for ethoxyethane, ensuring consistent availability for European industrial customers requiring this essential technical solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 1; Acute Tox. 4 *; STOT SE 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H224

Extremely flammable liquid and vapour.

H302

Harmful if swallowed.

H336

May cause drowsiness or dizziness.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1155
ADR Class3
Packing GroupI
Tunnel CodeD/E
Proper Shipping NameDiethylether
Marine PollutantNo

Frequently Asked Questions

What is ethoxyethane?

Ethoxyethane is an organic chemical compound with the molecular formula C4H10O and CAS number 60-29-7. Also commonly known as diethyl ether, it has a molecular weight of 74.12 g/mol and belongs to the ether family of compounds. This substance is classified as a highly flammable liquid with acute toxicity properties and specific target organ toxicity. It carries the danger signal word and requires careful handling due to its hazardous nature.

What are the physical and chemical properties of ethoxyethane?

Ethoxyethane is a colorless, volatile liquid with a characteristic sweet, pungent odor at room temperature. It has excellent solvent properties and is highly volatile, making it easily evaporable. The compound is relatively lightweight with its molecular mass of 74.12 g/mol and has low boiling point characteristics typical of ethers. Its chemical structure consists of two ethyl groups connected by an oxygen atom, giving it distinctive ether properties including high flammability and low flash point.

What is ethoxyethane used for?

Ethoxyethane serves primarily as a laboratory solvent and extraction agent in chemical processes. It is widely used in pharmaceutical manufacturing, organic synthesis, and analytical chemistry applications. The compound acts as an excellent solvent for fats, oils, waxes, and various organic compounds. In industrial settings, it functions as a reaction medium and extraction solvent. Its volatility and solvent properties make it valuable in chromatography and purification processes, though its use requires strict safety protocols.

How to handle ethoxyethane safely?

Ethoxyethane requires strict safety protocols including use of appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and respiratory protection when necessary. Work must be conducted in well-ventilated areas or under fume hoods to prevent vapor accumulation. Eliminate all ignition sources as the substance is extremely flammable (Class 1 flammable liquid). Use grounded equipment to prevent static electricity buildup and ensure emergency procedures are readily available for spill management and exposure incidents.

How to store ethoxyethane correctly?

Ethoxyethane must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its Class 1 flammable liquid classification. Use appropriate flame-resistant storage cabinets and ensure containers are tightly sealed to prevent vapor escape. Store away from oxidizing agents and incompatible materials. Maintain storage temperatures below recommended limits and implement proper inventory rotation. Ground all storage containers and transfer equipment to prevent static electricity accumulation during handling operations.

What to do in case of contact with ethoxyethane?

Ethoxyethane exposure requires immediate action depending on the contact route. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately and seek medical attention if breathing difficulties occur. For ingestion, do not induce vomiting and seek immediate medical assistance while providing safety data sheet information to medical personnel.

How to dispose of ethoxyethane appropriately?

Ethoxyethane disposal must comply with local and European waste regulations as hazardous chemical waste. The substance cannot be disposed of through regular waste streams due to its flammable and toxic properties. Contact licensed hazardous waste disposal companies for proper collection and treatment. Ensure containers are properly labeled and segregated from other waste types. Recovery or recycling may be possible through specialized facilities, but incineration at authorized high-temperature facilities is typically the preferred disposal method for contaminated materials.

How to transport ethoxyethane?

Ethoxyethane is classified under ADR Class 3 (flammable liquids), Packing Group I, indicating high danger level for transport. Shipments require proper dangerous goods packaging, labeling with appropriate hazard symbols, and transport documentation including safety data sheets. Vehicles must comply with ADR regulations including equipment requirements and route restrictions. Only trained personnel should handle transportation, and emergency response information must accompany shipments. Special precautions against static electricity and ignition sources are mandatory during loading and unloading operations.

Is ethoxyethane subject to specific regulations?

Ethoxyethane is regulated under European REACH and CLP regulations requiring registration and classification as Flam. Liq. 1; Acute Tox. 4; STOT SE 3 with danger signal word and GHS02, GHS07 pictograms. While not currently listed as a Substance of Very High Concern (SVHC), it requires safety data sheets and proper hazard communication. National regulations may impose additional restrictions on storage quantities, workplace exposure limits, and handling requirements. Users must ensure compliance with occupational safety regulations and environmental protection requirements in their respective countries.

Where to buy ethoxyethane in Europe?

Ethoxyethane is available through OYSI, a European distributor specializing in technical chemical products. As an established chemical supplier, OYSI can provide ethoxyethane with proper documentation including safety data sheets, certificates of analysis, and regulatory compliance information. Professional customers can contact OYSI for availability, specifications, and delivery options across European markets. Due to the substance's hazardous classification, purchases typically require demonstration of legitimate professional use and compliance with applicable safety and storage requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.