Ethyl acetate

C4H8O2

ethyl acetate

CAS141-78-6
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
141-78-6
EC Number
205-500-4
UN Number
1173
Index Number
607-022-00-5
PubChem CID
8857

Physical-chemical properties

Molecular Formula
C4H8O2
Molar Mass
88.11 g/mol
IUPAC Name
ethyl acetate

Chemical Identifiers

InChI
InChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
InChI Key
XEKOWRVHYACXOJ-UHFFFAOYSA-N

Overview

Ethyl acetate (CAS 141-78-6) is an ester compound with excellent solvent properties and characteristic fruity odor. This versatile organic solvent belongs to the acetate ester family and serves as one of the most widely used industrial solvents in Europe. With its molecular formula C4H8O2 and molar mass of 88.11 g/mol, ethyl acetate combines favorable physical properties with relatively low toxicity compared to many other organic solvents. The compound exhibits moderate volatility and complete miscibility with most organic solvents, while maintaining limited water solubility, making it ideal for extraction and purification processes. From a safety perspective, ethyl acetate is classified as a flammable liquid (Category 2) and requires appropriate fire prevention measures during handling and storage. The substance may cause eye irritation and can affect the central nervous system at high concentrations, necessitating adequate ventilation in work areas. Transport regulations classify it under ADR Class 3, reflecting its flammable nature. Industrial applications of ethyl acetate span multiple sectors, with primary uses in paint and coating formulations where it serves as an effective solvent for resins and polymers. The pharmaceutical and food industries utilize it extensively for extraction processes and as a processing aid. In the adhesives sector, ethyl acetate functions similarly to other acetate esters like propyl acetate, though with different evaporation rates and solvency characteristics. The printing industry also employs this solvent in ink formulations due to its clean evaporation profile. OYSI maintains reliable supplies of technical-grade ethyl acetate to support diverse industrial applications across European markets, ensuring consistent quality and regulatory compliance for our customers' manufacturing processes.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H336

May cause drowsiness or dizziness.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1173
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameEthylacetat
Marine PollutantNo

Frequently Asked Questions

What is ethyl acetate?

Ethyl acetate is an organic chemical compound with the molecular formula C4H8O2 and CAS number 141-78-6. It is an ester formed from ethanol and acetic acid, with a molecular weight of 88.11 g/mol. This colorless liquid is classified as a flammable liquid (Class 2) and carries danger warnings due to its eye irritation properties and specific target organ toxicity. It is widely used as a solvent in various industrial applications and is recognized by its characteristic sweet, fruity odor reminiscent of nail polish remover.

What are the physicochemical properties of ethyl acetate?

Ethyl acetate is a colorless, volatile liquid with a characteristic sweet, fruity odor. It has a molecular weight of 88.11 g/mol and boils at approximately 77°C. The compound is moderately soluble in water (about 8.3% at 20°C) but miscible with most organic solvents including alcohols, ethers, and hydrocarbons. It has a relatively low viscosity and density of about 0.9 g/cm³. Its high volatility and low boiling point make it an excellent solvent that evaporates quickly at room temperature.

What is ethyl acetate used for?

Ethyl acetate is primarily used as a solvent in various industrial applications including paints, coatings, inks, and adhesives. It serves as an extraction solvent in pharmaceutical manufacturing and food processing industries. The compound is widely used in nail polish removers and other cosmetic products due to its effective dissolving properties and relatively low toxicity. It also finds applications in the production of artificial flavors, decaffeination of coffee and tea, and as a cleaning agent in electronics manufacturing.

How to handle ethyl acetate safely?

Ethyl acetate must be handled with appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing to prevent eye and skin contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation of vapors. Due to its flammable nature (Flam. Liq. 2), eliminate all ignition sources and use explosion-proof equipment. Avoid static electricity buildup and ensure proper grounding of containers. Emergency shower and eyewash facilities should be readily accessible when working with this substance.

How to store ethyl acetate correctly?

Ethyl acetate should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable classification (Class 3, Group II). Use only approved containers and keep them tightly sealed to prevent vapor release. Storage areas must be equipped with appropriate fire suppression systems and maintained below 25°C when possible. Keep away from oxidizing agents and strong acids or bases. Ensure adequate spacing between containers and provide proper secondary containment to prevent spill spread.

What to do in case of contact with ethyl acetate?

In case of skin contact with ethyl acetate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately and seek medical attention if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a healthcare professional after significant exposure incidents.

How to dispose of ethyl acetate properly?

Ethyl acetate must be disposed of according to local, national, and international environmental regulations as hazardous waste. The substance cannot be discharged into sewers, waterways, or soil. Contact licensed waste disposal companies for proper collection and treatment. Small quantities may be recovered through distillation for reuse. Contaminated materials like rags or absorbents should also be treated as hazardous waste. Always consult your local environmental authority for specific disposal requirements and approved disposal facilities in your region.

How to transport ethyl acetate?

Ethyl acetate is classified under ADR as Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations. It must be transported in UN-approved packaging with proper labeling including GHS02 and GHS07 pictograms and 'Danger' signal word. Vehicles must carry appropriate fire extinguishing equipment and drivers need ADR certification. Transport documents must include the proper shipping name, UN number, and emergency response information. Ensure adequate ventilation during transport and avoid exposure to heat sources or mechanical impacts that could cause container damage.

Is ethyl acetate subject to particular regulations?

Ethyl acetate is regulated under various European legislations including REACH and CLP regulations. It must be classified and labeled according to CLP with pictograms GHS02 and GHS07, and the danger signal word due to its flammable and eye irritation properties. The substance is not currently listed as a Substance of Very High Concern (SVHC) under REACH. Industrial users must comply with workplace exposure limits and may need to prepare safety data sheets. Specific restrictions may apply depending on the intended use and concentration in mixtures.

Where to buy ethyl acetate in Europe?

Ethyl acetate is available through OYSI, a European distributor specializing in technical chemicals for industrial applications. OYSI provides high-quality ethyl acetate with comprehensive documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures regulatory compliance and reliable supply chains across European markets. For pricing, availability, and technical specifications tailored to your specific application requirements, contact OYSI directly through their sales channels to discuss your ethyl acetate procurement needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.