Ethyl acetate

C4H8O2

ethyl acetate

CAS141-78-6
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
141-78-6
EC Number
205-500-4
UN Number
1173
Index Number
607-022-00-5
PubChem CID
8857

Physical-chemical properties

Molecular Formula
C4H8O2
Molar Mass
88.11 g/mol
IUPAC Name
ethyl acetate

Chemical Identifiers

InChI
InChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
InChI Key
XEKOWRVHYACXOJ-UHFFFAOYSA-N

Overview

Ethyl acetate (CAS 141-78-6) is an organic ester solvent with excellent dissolving properties and characteristic fruity odor. This versatile chemical compound, also known by its IUPAC name ethyl acetate, represents one of the most widely used ester solvents in industrial applications. With the molecular formula C4H8O2 and a molecular weight of 88.11 g/mol, ethyl acetate demonstrates exceptional performance characteristics that make it indispensable across numerous sectors. The substance belongs to the same chemical family as propyl acetate and shares similar solvent properties with compounds like 3-methylbutyl formate, though each offers distinct advantages depending on the specific application requirements. As a Class 2 flammable liquid under GHS classification, ethyl acetate requires appropriate handling precautions. The substance carries the signal word "Danger" and is associated with pictograms GHS02 and GHS07, indicating its flammable nature and potential for eye irritation (Eye Irrit. 2) and specific target organ toxicity following single exposure (STOT SE 3). Its ADR classification as Class 3 reflects its transportation requirements as a flammable liquid, with EC number 205-500-4 confirming its regulatory status within European markets. The compound's excellent solvency power, relatively low toxicity compared to other organic solvents, and favorable evaporation rate make it particularly valuable in paint and coating formulations, where it provides optimal viscosity control and film formation. In the pharmaceutical industry, ethyl acetate serves as a critical extraction and purification solvent, while the food industry utilizes its natural occurrence and pleasant aroma in flavor applications. OYSI maintains reliable supply chains for ethyl acetate to support diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H336

May cause drowsiness or dizziness.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1173
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameEthylacetat
Marine PollutantNo

Frequently Asked Questions

What is ethyl acetate?

Ethyl acetate is an organic chemical compound with the molecular formula C4H8O2 and CAS number 141-78-6. It is an ester formed from ethanol and acetic acid, with a molecular weight of 88.11 g/mol. This colorless liquid is widely used as a solvent in various industrial applications due to its excellent dissolving properties and relatively low toxicity compared to other organic solvents.

What are the physicochemical properties of ethyl acetate?

Ethyl acetate is a colorless liquid with a characteristic sweet, fruity odor reminiscent of nail polish remover. It has excellent solvent properties and is moderately soluble in water but miscible with most organic solvents. The compound is highly volatile at room temperature and has a relatively low boiling point, making it useful for applications requiring rapid evaporation.

What is ethyl acetate used for?

Ethyl acetate is primarily used as a solvent in paints, coatings, adhesives, and printing inks due to its excellent dissolving properties. It serves as a key ingredient in nail polish removers and is widely used in the pharmaceutical industry for drug extraction and purification processes. Additionally, it finds applications in the food industry as a flavoring agent and in laboratories as an extraction solvent.

How to handle ethyl acetate safely?

Ethyl acetate requires careful handling due to its flammable nature (Flam. Liq. 2) and potential for eye irritation (Eye Irrit. 2). Workers should wear appropriate personal protective equipment including safety goggles, gloves, and ensure adequate ventilation to prevent vapor accumulation. The substance can cause specific target organ toxicity (STOT SE 3), so exposure should be minimized and work areas should be well-ventilated.

How to store ethyl acetate correctly?

Ethyl acetate must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable properties. Containers should be tightly sealed to prevent vapor escape and stored in accordance with local fire prevention regulations. The storage area should be equipped with appropriate fire suppression systems and incompatible materials should be kept separate.

What to do in case of contact with ethyl acetate?

In case of skin contact with ethyl acetate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water. For eye contact, flush immediately with plenty of clean water for at least 15 minutes and seek medical attention if irritation persists. If inhaled, move the person to fresh air and seek medical advice if respiratory symptoms develop.

How to dispose of ethyl acetate properly?

Ethyl acetate waste must be disposed of in accordance with local and national hazardous waste regulations. The substance should not be poured down drains or into the environment. Waste should be collected in appropriate containers and disposed of through licensed waste management companies specializing in flammable solvents. Recovery and recycling options should be considered where possible to minimize environmental impact.

How to transport ethyl acetate?

Ethyl acetate is classified as ADR Class 3 (flammable liquids), Packing Group II for transportation purposes. It must be packaged in approved containers meeting UN specification requirements and transported by qualified carriers with appropriate hazardous goods training. Vehicles must carry proper placarding and documentation, and drivers must have valid ADR certification for transporting flammable liquids.

Is ethyl acetate subject to specific regulations?

Ethyl acetate is subject to CLP regulation classification as Flam. Liq. 2, STOT SE 3, and Eye Irrit. 2, requiring appropriate labeling with GHS02 and GHS07 pictograms and the signal word 'Danger'. It falls under REACH registration requirements for manufacturers and importers. The substance is not classified as a Substance of Very High Concern (SVHC), but users must comply with occupational exposure limits and safety data sheet requirements.

Where to buy ethyl acetate in Europe?

Ethyl acetate is available through OYSI, a European distributor of technical chemicals offering reliable supply across Europe. OYSI provides quality ethyl acetate with proper documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures compliance with European regulations and offers professional technical support to help customers with their specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.