(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea

C7H6Cl2N4S

CAS5836-73-7
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
5836-73-7
UN Number
2757
Index Number
616-016-00-1
PubChem CID
5483266

Physical-chemical properties

Molecular Formula
C7H6Cl2N4S
Molar Mass
249.12 g/mol
IUPAC Name
(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea

Chemical Identifiers

InChI
InChI=1S/C7H6Cl2N4S/c8-5-2-1-4(3-6(5)9)11-13-12-7(10)14/h1-3H,(H3,10,11,12,14)
InChI Key
BOQUJWASRWDQOS-UHFFFAOYSA-N

Overview

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea (CAS 5836-73-7) is an organosulfur compound featuring dichlorophenyl and hydrazinylidene functional groups with significant toxicological properties. This specialized chemical compound belongs to the thiourea derivative family and presents a molecular structure characterized by the presence of two chlorine atoms on the phenyl ring, combined with hydrazinylidene and thiourea moieties. With a molecular formula of C7H6Cl2N4S and a molecular weight of 249.12 g/mol, this substance exhibits distinct chemical properties that make it valuable for specific industrial applications while requiring careful handling protocols. The compound is classified under acute toxicity category 2, necessitating strict safety measures during storage, handling, and transportation. The GHS06 pictogram and "Danger" signal word indicate its potential health hazards, while its ADR class 6.1 classification reflects its toxic nature for shipping purposes. These safety characteristics are similar to other chlorinated aromatic compounds such as chloromethylbenzene, which also requires specialized handling procedures in industrial settings. Industrial applications of (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea primarily include its use as an intermediate in pharmaceutical synthesis, particularly in the development of compounds requiring thiourea-based chemistry. The compound also finds application in analytical chemistry as a reagent for metal detection and complexation studies. Additionally, it serves as a building block in the synthesis of specialized organic compounds where the unique combination of dichlorophenyl and thiourea functionalities is required. Like other nitrogen-containing aromatics such as N-methylaniline, this compound requires expertise in handling and storage to ensure workplace safety and regulatory compliance. OYSI provides this specialized chemical compound to qualified industrial customers across Europe, supporting advanced chemical synthesis and research applications.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H300

Fatal if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2757
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NamePromurit
Marine PollutantNo

Frequently Asked Questions

What is (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea is an organic chemical compound with the molecular formula C7H6Cl2N4S and CAS number 5836-73-7. This substance belongs to the thiourea derivative family and contains dichlorophenyl and hydrazinylidene functional groups. With a molecular weight of 249.12 g/mol, it is classified as highly toxic (Acute Tox. 2) and requires careful handling procedures in industrial applications.

What are the physicochemical properties of (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea is a solid organic compound at room temperature with a molecular weight of 249.12 g/mol. The substance contains chlorine atoms and sulfur in its structure, which influence its chemical stability and reactivity. As a thiourea derivative with dichlorophenyl substitution, it exhibits specific solubility characteristics in organic solvents. Detailed physical properties should be confirmed through technical datasheets from suppliers.

What is (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea used for?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea is primarily used as an intermediate in pharmaceutical synthesis and chemical research applications. Its thiourea structure makes it valuable in organic synthesis reactions, particularly in the development of bioactive compounds. The dichlorophenyl group provides specific reactivity for targeted chemical transformations. Given its high toxicity classification, its use is restricted to professional industrial and research environments with appropriate safety measures.

How to handle (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea safely?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea requires strict safety protocols due to its Acute Tox. 2 classification and GHS06 pictogram. Mandatory personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Personnel should be trained in emergency procedures and have access to safety data sheets before handling this dangerous substance.

How to store (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea correctly?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea must be stored in a secure, well-ventilated area away from incompatible materials. Keep containers tightly closed in a cool, dry place with restricted access due to its high toxicity. Storage areas should have appropriate warning signs and emergency equipment. Avoid exposure to heat, moisture, and incompatible chemicals. Regular inventory checks and proper labeling are essential for safe storage management of this hazardous substance.

What to do in case of contact with (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea?

Immediate medical attention is required for any contact with (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea due to its high toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with clean water continuously. For ingestion, do not induce vomiting and seek emergency medical care. Always consult the safety data sheet for complete first aid procedures.

How to dispose of (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea appropriately?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea must be disposed of as hazardous waste through licensed waste management companies in accordance with local and European regulations. Due to its high toxicity classification, it cannot be disposed of with regular chemical waste. Incineration at high temperatures in specialized facilities is typically required. All disposal activities must comply with ADR transport regulations and waste tracking documentation requirements for dangerous substances.

How to transport (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea is classified under ADR Class 6.1 (toxic substances) Packing Group I, indicating high danger during transport. Special packaging requirements, labeling, and documentation are mandatory for shipment. Transport vehicles must comply with ADR regulations for toxic materials, including appropriate placarding and driver certification. Only certified dangerous goods carriers should handle transportation, with emergency response information readily available throughout the shipping process.

Is (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea subject to specific regulations?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea is subject to European REACH and CLP regulations due to its chemical classification. The substance is not currently identified as an SVHC (Substance of Very High Concern). However, its Acute Tox. 2 classification requires compliance with strict labeling, safety data sheet, and handling requirements. Users must ensure proper registration and authorization for industrial use, following all applicable chemical safety regulations in their jurisdiction.

Where to buy (E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea in Europe?

(E)-[(3,4-dichlorophenyl)hydrazinylidene]thiourea is available through OYSI, a specialized European distributor of technical chemicals. As a professional supplier, OYSI provides this substance exclusively to qualified industrial and research customers with appropriate safety certifications. The company ensures compliance with all regulatory requirements, proper packaging, and comprehensive documentation. Contact OYSI directly for availability, technical specifications, and regulatory support for this controlled hazardous substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.