2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine
C12H19N6OP
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Identification
- CAS Number
- 1031-47-6
- UN Number
- 2783
- Index Number
- 015-024-00-7
- PubChem CID
- 13943
Physical-chemical properties
- Molecular Formula
- C12H19N6OP
- Molar Mass
- 294.29 g/mol
- IUPAC Name
- 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine
Chemical Identifiers
- InChI
- InChI=1S/C12H19N6OP/c1-16(2)20(19,17(3)4)18-12(13)14-11(15-18)10-8-6-5-7-9-10/h5-9H,1-4H3,(H2,13,14,15)
- InChI Key
- BABJTMNVJXLAEX-UHFFFAOYSA-N
Overview
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine (CAS 1031-47-6) is an organophosphorus compound featuring both triazole and phosphoramide functional groups with significant biological activity potential. This specialized chemical compound represents a unique intersection of organophosphorus chemistry and heterocyclic triazole structures. With its molecular formula C12H19N6OP and molecular weight of 294.29 g/mol, this substance exhibits the characteristic properties of both phosphoramide derivatives and nitrogen-rich heterocycles. The compound's structure incorporates a phenyl-substituted 1,2,4-triazole ring system linked to a bis(dimethylamino)phosphoryl group, creating a molecule with distinctive chemical and biological properties. The safety profile of this compound requires careful attention, as indicated by its Acute Toxicity Category 1 and 2 classifications under GHS. The presence of the skull and crossbones pictogram (GHS06) and "Danger" signal word emphasizes the need for appropriate handling procedures and protective equipment. Transportation falls under ADR Class 6.1, reflecting its toxic nature and requiring specialized shipping protocols. In industrial applications, compounds of this type are primarily utilized in pharmaceutical research and development, particularly in studies involving enzyme inhibition and bioactive compound synthesis. The organophosphorus moiety makes it valuable for research into acetylcholinesterase inhibitors, while the triazole component contributes to antifungal and antimicrobial research applications. Similar compounds in this chemical family include N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine, which shares the phosphoramide functionality, and other organophosphorus derivatives used in biological studies. OYSI maintains availability of this specialized research compound for qualified industrial and research customers requiring high-purity organophosphorus materials.
Safety & Classification
Acute Tox. 1; Acute Tox. 2 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2783 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Triamiphos (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is a specialized organophosphorus compound with CAS number 1031-47-6. This chemical features a triazole ring system combined with phosphoryl and phenyl functional groups, giving it a molecular formula of C12H19N6OP and molecular weight of 294.29 g/mol. It is classified as highly toxic with acute toxicity categories 1 and 2, requiring extreme caution in handling and use.
What are the physicochemical properties of 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is an organophosphorus compound with a molecular weight of 294.29 g/mol and formula C12H19N6OP. The compound contains multiple nitrogen atoms within its triazole structure, along with dimethylamino groups attached to a phosphoryl moiety. Its specific physical properties such as melting point, boiling point, and solubility characteristics should be confirmed through technical data sheets from suppliers.
What is 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine used for?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is primarily used in specialized chemical research and pharmaceutical intermediate synthesis. The compound's unique triazole-phosphoryl structure makes it valuable for developing pharmaceutical compounds, agrochemical products, and advanced materials. Its applications are typically limited to professional laboratory and industrial settings due to its high acute toxicity classification, requiring specialized handling protocols and expertise.
How to handle 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine safely?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine requires extreme safety precautions due to its Acute Tox. 1 and 2 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles, respiratory protection, and full protective clothing. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion completely. Only trained personnel should handle this substance, following strict safety protocols and emergency procedures.
How to store 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine correctly?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine must be stored in a secure, well-ventilated area away from heat, ignition sources, and incompatible materials. Keep containers tightly sealed and clearly labeled with appropriate hazard warnings. Storage should be limited to authorized personnel only, with restricted access due to the high acute toxicity. Maintain appropriate temperature conditions and ensure compatibility with storage materials to prevent degradation or dangerous reactions.
What to do in case of contact with 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine?
Immediate medical attention is required for any contact with 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine due to its extreme toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled or ingested, seek emergency medical care immediately. Do not induce vomiting unless directed by medical professionals. Have safety data sheet available for medical personnel.
How to dispose of 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine appropriately?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine must be disposed of as hazardous waste according to local and international regulations. The substance requires specialized treatment due to its acute toxicity classification and cannot be disposed of through regular waste streams. Contact licensed hazardous waste disposal companies for proper collection and treatment. Maintain detailed waste disposal records and ensure compliance with REACH, national waste regulations, and transport requirements during disposal.
How to transport 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is classified as ADR Class 6.1 (toxic substances), Packing Group II, requiring specialized dangerous goods transport procedures. Shipments must use approved packaging, proper labeling with GHS06 pictograms, and appropriate transport documentation. Only certified dangerous goods carriers can transport this material. Packages must be clearly marked with hazard warnings and emergency contact information, following strict ADR/IMDG/IATA dangerous goods regulations.
Is 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine subject to specific regulations?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is subject to strict chemical safety regulations including REACH registration requirements and CLP classification as Acute Tox. 1 and 2. The substance is not currently listed as SVHC but requires comprehensive safety data sheets, hazard communication, and restricted handling procedures. Companies must comply with occupational safety regulations, transport restrictions under ADR Class 6.1, and potential national restrictions on toxic substances.
Where to buy 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine in Europe?
2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this highly regulated substance to qualified industrial and research customers with proper handling capabilities. Due to the extreme toxicity classification, purchases require verification of appropriate safety protocols, trained personnel, and legitimate industrial applications. Contact OYSI directly for availability, technical specifications, and regulatory compliance documentation.
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2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.