2-chloro-N,N,6-trimethylpyrimidin-4-amine

2-chloro-N,N,6-trimethylpyrimidin-4-amine is a chlorinated pyrimidine derivative with the molecular formula C7H10ClN3 and CAS number 535-89-7. This organic compound has a molecular weight of 171.63 g/mol and belongs to the class of substituted pyrimidines. It is classified as an acute toxicity hazard (Acute Tox. 2) and requires careful handling due to its dangerous properties. The compound features a pyrimidine ring substituted with chlorine and multiple methyl groups.

2-chloro-N,N,6-trimethylpyrimidin-4-amine is an organic solid with a molecular weight of 171.63 g/mol and formula C7H10ClN3. As a chlorinated pyrimidine derivative, it typically appears as a crystalline solid at room temperature. The compound contains both hydrophobic (methyl groups) and polar (amino and pyrimidine) regions, affecting its solubility profile. Its physical state and appearance may vary depending on purity and crystalline form.

2-chloro-N,N,6-trimethylpyrimidin-4-amine is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Pyrimidine derivatives like this compound serve as building blocks for developing active pharmaceutical ingredients, particularly in the synthesis of antiviral, anticancer, and antimicrobial agents. It may also be used in research applications for developing new therapeutic compounds or as a reagent in organic synthesis reactions involving pyrimidine chemistry.

2-chloro-N,N,6-trimethylpyrimidin-4-amine requires strict safety measures due to its Acute Tox. 2 classification and GHS06 pictogram. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact completely. Use proper handling procedures including secondary containment and have emergency eyewash and shower facilities readily accessible.

2-chloro-N,N,6-trimethylpyrimidin-4-amine should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly sealed and store separately from incompatible materials such as strong oxidizers, acids, and bases. Due to its acute toxicity classification, storage must be in designated hazardous chemical areas with restricted access. Maintain proper labeling and ensure compatibility with container materials to prevent degradation or dangerous reactions.

Immediate action is critical due to the compound's Acute Tox. 2 classification. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and rinse mouth with water. Seek immediate medical attention in all cases and provide the safety data sheet to medical personnel.

2-chloro-N,N,6-trimethylpyrimidin-4-amine must be disposed of as hazardous waste according to local and European waste regulations. Due to its acute toxicity classification, it cannot be disposed of through regular waste streams. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require incineration at high temperatures in specialized facilities. Always consult local environmental authorities and follow waste classification codes for proper documentation and disposal procedures.

2-chloro-N,N,6-trimethylpyrimidin-4-amine is classified under ADR Class 6.1 (Toxic substances) Packing Group I, indicating high toxicity requiring strict transport regulations. Packages must meet UN specification standards for Packing Group I materials and display appropriate hazard labels and markings. Transport documents must include proper shipping names, hazard classes, and emergency response information. Only authorized carriers trained in hazardous materials transport should handle shipments, following ADR requirements for routing and vehicle specifications.

2-chloro-N,N,6-trimethylpyrimidin-4-amine is subject to European REACH regulation for chemical registration and evaluation, though it is not classified as an SVHC (Substance of Very High Concern). The compound falls under CLP regulation for hazard classification and labeling requirements, requiring GHS06 pictograms and 'Danger' signal words. As an Acute Tox. 2 substance, it may be subject to additional restrictions regarding use, handling, and workplace exposure limits in various EU member states.

2-chloro-N,N,6-trimethylpyrimidin-4-amine is available through OYSI, a specialized European distributor of technical chemicals serving pharmaceutical and chemical industries. OYSI provides this compound to qualified industrial customers with proper handling capabilities and regulatory compliance. Due to its acute toxicity classification, purchases require appropriate licensing and safety documentation. Contact OYSI directly to discuss availability, specifications, packaging options, and regulatory requirements for your specific application and location within Europe.