Diethoxyphosphoryl diethyl phosphate

C8H20O7P2

diethoxyphosphoryl diethyl phosphate

CAS107-49-3
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
107-49-3
EC Number
203-495-3
UN Number
3018
Index Number
015-025-00-2
PubChem CID
7873

Physical-chemical properties

Molecular Formula
C8H20O7P2
Molar Mass
290.19 g/mol
IUPAC Name
diethoxyphosphoryl diethyl phosphate

Chemical Identifiers

InChI
InChI=1S/C8H20O7P2/c1-5-11-16(9,12-6-2)15-17(10,13-7-3)14-8-4/h5-8H2,1-4H3
InChI Key
IDCBOTIENDVCBQ-UHFFFAOYSA-N

Overview

Diethoxyphosphoryl diethyl phosphate (CAS 107-49-3) is an organophosphorus compound featuring dual phosphate ester groups with significant toxicological properties. This chemical substance, also known by its EC number 203-495-3, belongs to the family of phosphoric acid derivatives and presents a molecular formula of C8H20O7P2 with a molecular weight of 290.19 g/mol. As an organophosphorus compound, diethoxyphosphoryl diethyl phosphate exhibits considerable biological activity, which necessitates strict handling protocols due to its acute toxicity classification (Acute Tox. 1 and 2). The substance carries the danger signal word and requires GHS06 and GHS09 pictograms, indicating both acute toxicity and environmental hazards, particularly aquatic toxicity. Its ADR classification as Class 6.1 confirms its status as a toxic substance requiring specialized transport conditions. The compound's dual phosphate ester structure distinguishes it from simpler organophosphorus derivatives, sharing some structural characteristics with other complex phosphorus-containing molecules, though it differs significantly from compounds like diethoxy-(2-ethylsulfanylethoxy)-sulfanylidene-lambda5-phosphane in terms of molecular architecture and reactivity patterns. Industrial applications of diethoxyphosphoryl diethyl phosphate primarily include use as an intermediate in organophosphorus chemistry, flame retardant formulations, and specialized chemical synthesis processes. The pharmaceutical industry also utilizes this compound in the production of certain active pharmaceutical ingredients where phosphorus-containing moieties are required. Additionally, it serves as a reagent in research applications focusing on phosphorylation reactions and enzyme studies. OYSI maintains reliable supply chains for diethoxyphosphoryl diethyl phosphate, ensuring consistent availability for European industrial customers requiring this specialized organophosphorus compound.

Safety & Classification

Danger
Classification:

Acute Tox. 1; Acute Tox. 2 *; Aquatic Acute 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3018
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameTEPP (ISO)
Marine PollutantNo

Frequently Asked Questions

What is diethoxyphosphoryl diethyl phosphate?

Diethoxyphosphoryl diethyl phosphate is an organophosphorus compound with the molecular formula C8H20O7P2 and CAS number 107-49-3. This chemical substance has a molecular weight of 290.19 g/mol and belongs to the category of phosphate esters. It is classified as highly toxic with acute toxicity class 1 and 2, requiring careful handling and specialized safety measures. The compound also presents environmental hazards, particularly to aquatic ecosystems.

What are the physicochemical properties of diethoxyphosphoryl diethyl phosphate?

Diethoxyphosphoryl diethyl phosphate is an organophosphorus liquid compound with a molecular formula C8H20O7P2 and molecular weight of 290.19 g/mol. As a phosphate ester, it typically exhibits moderate to good solubility in organic solvents while having limited water solubility. The compound contains multiple ethoxy and phosphate groups, contributing to its chemical reactivity. Specific physical properties such as boiling point, density, and viscosity require consultation of detailed technical datasheets for precise values.

What is diethoxyphosphoryl diethyl phosphate used for?

Diethoxyphosphoryl diethyl phosphate is primarily used as an intermediate in the synthesis of organophosphorus compounds and specialty chemicals. Its applications include use in pharmaceutical synthesis, agrochemical manufacturing, and as a reagent in organic chemistry reactions. The compound may also serve as a precursor for flame retardants and plasticizers. Due to its high toxicity classification, its use is restricted to professional industrial applications with appropriate safety controls and regulatory compliance.

How to handle diethoxyphosphoryl diethyl phosphate safely?

Diethoxyphosphoryl diethyl phosphate requires extreme caution during handling due to its Acute Tox. 1 and 2 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, full face protection, and appropriate respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion completely. Emergency shower and eyewash facilities must be readily accessible. Only trained personnel should handle this substance following strict safety protocols.

How to store diethoxyphosphoryl diethyl phosphate correctly?

Diethoxyphosphoryl diethyl phosphate must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Containers should be tightly sealed and made of compatible materials resistant to organophosphorus compounds. Storage areas must be secured with restricted access due to the high toxicity classification. Temperature control and protection from direct sunlight are essential. Separation from oxidizing agents, strong acids, and bases is required to prevent dangerous reactions.

What to do in case of contact with diethoxyphosphoryl diethyl phosphate?

Immediate action is critical due to the high toxicity of diethoxyphosphoryl diethyl phosphate. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting. Seek immediate medical attention in all cases and provide safety data sheet to medical personnel.

How to dispose of diethoxyphosphoryl diethyl phosphate properly?

Diethoxyphosphoryl diethyl phosphate requires disposal as hazardous waste through licensed waste management companies due to its high toxicity and environmental hazard classifications. The substance cannot be disposed of in regular waste streams or sewage systems. Disposal must comply with local, national, and European waste regulations including the Waste Framework Directive. Professional hazardous waste contractors must handle collection, treatment, and final disposal. Container residues also require hazardous waste treatment.

How to transport diethoxyphosphoryl diethyl phosphate?

Diethoxyphosphoryl diethyl phosphate is classified under ADR Class 6.1 (toxic substances) Packing Group I, indicating high toxicity requiring maximum packaging protection. Transportation must comply with dangerous goods regulations including proper packaging, labeling with GHS06 and GHS09 pictograms, and documentation. Only certified carriers trained in hazardous materials transport should handle shipments. Emergency response information must accompany shipments. Special vehicle requirements and route restrictions may apply depending on quantity and destination.

Is diethoxyphosphoryl diethyl phosphate subject to specific regulations?

Diethoxyphosphoryl diethyl phosphate is subject to multiple European regulations including REACH registration requirements and CLP classification as Acute Tox. 1/2 and Aquatic Acute 1. The compound requires safety data sheets compliant with current regulations. While not currently listed as SVHC, its high toxicity classification subjects it to strict occupational health and safety requirements. Additional restrictions may apply for certain uses, and regulatory status should be verified regularly as classifications can change.

Where to buy diethoxyphosphoryl diethyl phosphate in Europe?

Diethoxyphosphoryl diethyl phosphate is available through OYSI, a specialized European distributor of technical chemicals. As a highly toxic substance requiring professional handling, it is only supplied to qualified industrial customers with appropriate safety infrastructure and regulatory compliance. OYSI provides comprehensive documentation including safety data sheets and certificates of analysis. Due to the dangerous nature of this compound, sales are restricted to legitimate industrial applications with proper safety protocols in place.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.