Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate is an organophosphate compound with the molecular formula C8H15N2O4P and CAS number 108-34-9. This chemical substance has a molecular weight of 234.19 g/mol and belongs to the class of phosphate esters containing a pyrazole ring. It is classified as highly toxic with acute toxicity categories 1 and 2, requiring careful handling and specialized safety measures in professional applications.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate is an organic phosphate ester with specific physicochemical characteristics determined by its molecular structure. The compound contains both phosphate and pyrazole functional groups, which influence its solubility and stability properties. As an organophosphate, it typically exhibits moderate to good solubility in organic solvents. The presence of the pyrazole ring and phosphate ester linkages affects its chemical reactivity and physical state under standard conditions.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate serves as a specialized chemical intermediate in organic synthesis and pharmaceutical research applications. The compound's unique structure, combining phosphate ester and pyrazole functionalities, makes it valuable for developing bioactive molecules and conducting chemical research. Its applications are typically limited to professional laboratory settings and industrial processes requiring high purity organophosphate compounds with specific structural features.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate requires extreme caution due to its Acute Tox. 1 and 2 classifications with GHS06 pictogram. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Avoid skin contact, inhalation, and ingestion completely. Work with minimal quantities, use proper laboratory techniques, and ensure emergency procedures are readily available. Only trained personnel should handle this highly toxic substance.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate must be stored in a secure, temperature-controlled environment away from incompatible materials. Keep containers tightly sealed in a cool, dry place with restricted access due to its high toxicity classification. Store separately from oxidizing agents, bases, and moisture-sensitive areas. Ensure proper labeling with hazard warnings and maintain inventory records. Storage areas should have appropriate ventilation, spill containment measures, and emergency response equipment readily accessible.

Immediate medical attention is critical due to the substance's Acute Tox. 1 classification. For skin contact, remove contaminated clothing and flush thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical help. For eye contact, rinse continuously with water and remove contact lenses if present. Never induce vomiting if ingested. Contact poison control and emergency services immediately, providing the safety data sheet to medical personnel.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate requires specialized hazardous waste disposal due to its high toxicity classification. Contact licensed hazardous waste disposal companies authorized to handle toxic organophosphate compounds. Never dispose of in regular waste streams, sewers, or soil. Follow local and national regulations for toxic substance disposal, maintain proper documentation, and use appropriate packaging for waste transport. Incineration at authorized high-temperature facilities is typically the preferred disposal method.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate is classified under ADR Class 6.1, Packing Group I, indicating highly toxic substances requiring stringent transport regulations. Packaging must comply with UN specifications for toxic materials, with proper hazard labels and documentation. Only certified carriers experienced in hazardous materials transport should handle shipments. Transport vehicles require appropriate placarding, emergency response information, and compliance with routing restrictions for highly toxic substances.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate is subject to comprehensive chemical regulations including REACH registration requirements, CLP classification as highly toxic, and transport regulations under ADR Class 6.1. The substance is not currently listed as SVHC but may be subject to additional restrictions due to its acute toxicity classification. Users must comply with occupational exposure limits, workplace safety regulations, and proper notification requirements for handling highly toxic substances.

Diethyl (5-methyl-1H-pyrazol-3-yl) phosphate is available through OYSI, a specialized European distributor of technical chemicals and laboratory reagents. OYSI provides this highly regulated substance to qualified customers with proper handling capabilities and regulatory compliance. Due to the substance's high toxicity classification, purchases require verification of appropriate facilities, trained personnel, and legitimate research or industrial applications. Contact OYSI directly for availability, regulatory documentation, and technical support.