Thiourea

CH4N2S

thiourea

CAS62-56-6
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
62-56-6
EC Number
200-543-5
UN Number
3077
Index Number
612-082-00-0
PubChem CID
2723790

Physical-chemical properties

Molecular Formula
CH4N2S
Molar Mass
76.12 g/mol
IUPAC Name
thiourea

Chemical Identifiers

InChI
InChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
InChI Key
UMGDCJDMYOKAJW-UHFFFAOYSA-N

Overview

Thiourea (CAS 62-56-6) is an organosulfur compound with the molecular formula CH4N2S, characterized by its crystalline structure and versatile chemical reactivity in industrial applications. This white crystalline solid, also known by its IUPAC name thiourea, serves as a fundamental building block in numerous chemical processes across various industries. With a molecular weight of 76.12 g/mol, thiourea contains both sulfur and nitrogen functional groups, making it particularly valuable as a reducing agent, complexing agent, and intermediate in organic synthesis. The compound's unique chemical structure allows it to participate in diverse reactions, from metal extraction processes to pharmaceutical manufacturing. Safety considerations are paramount when handling thiourea, as it carries significant health hazards including carcinogenic and reproductive toxicity properties (Carc. 2; Repr. 2), along with acute toxicity classification (Acute Tox. 4). The substance requires careful handling protocols due to its GHS08, GHS07, and GHS09 pictogram classifications and is classified under ADR Class 9 for transportation purposes. Environmental precautions are also necessary given its aquatic chronic toxicity classification. Industrial applications of thiourea span multiple sectors, including metal processing where it functions as a complexing agent in electroplating and mining operations, photographic industry applications as a fixing agent, and pharmaceutical synthesis as an intermediate compound. Unlike structurally different compounds such as 1,4-dichlorobenzene which serves primarily as a solvent, thiourea's dual nitrogen-sulfur functionality enables its use in specialized chemical transformations and metal coordination chemistry. OYSI maintains reliable supply chains for thiourea to support European industrial customers requiring this essential chemical intermediate for their manufacturing processes.

Safety & Classification

Warning
Classification:

Carc. 2; Repr. 2; Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameThioharnstoff, fest
Marine PollutantNo

Frequently Asked Questions

What is thiourea?

Thiourea is an organic sulfur-containing compound with the molecular formula CH4N2S and CAS number 62-56-6. This crystalline substance has a molecular weight of 76.12 g/mol and belongs to the family of thiocarbamide compounds. It is classified as a hazardous chemical with carcinogenic and reproductive toxicity properties, requiring careful handling in industrial and laboratory applications.

What are the physicochemical properties of thiourea?

Thiourea is a white crystalline solid at room temperature with high water solubility. It has a molecular mass of 76.12 g/mol and contains sulfur, nitrogen, and carbon atoms in its structure. The compound is stable under normal conditions but can decompose when heated. It exhibits good solubility in polar solvents, making it useful for various chemical processes and reactions.

What is thiourea used for?

Thiourea is primarily used in pharmaceutical synthesis, rubber vulcanization accelerators, and photographic processing. It serves as an intermediate in the production of various chemicals and pharmaceuticals. The compound is also utilized in analytical chemistry as a reagent, in textile processing, and in certain metal extraction processes. Its unique chemical properties make it valuable for specialized industrial applications.

How to handle thiourea safely?

Thiourea requires strict safety measures due to its carcinogenic and reproductive toxicity properties (Carc. 2; Repr. 2). Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Follow proper hygiene practices and wash hands thoroughly after handling.

How to store thiourea correctly?

Thiourea should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled according to GHS requirements. Store separately from oxidizing agents and acids to prevent dangerous reactions. Ensure storage areas have appropriate containment measures and access restrictions due to the substance's hazardous classification.

What to do in case of contact with thiourea?

Thiourea exposure requires immediate action due to its acute toxicity (Acute Tox. 4). For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with water for 15 minutes. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete first aid procedures.

How to dispose of thiourea appropriately?

Thiourea disposal must comply with local and national hazardous waste regulations due to its classification as carcinogenic and environmentally hazardous (Aquatic Chronic 2). Contact licensed waste disposal companies for proper treatment and disposal. Do not discharge into drains, soil, or water bodies. Collect waste in appropriate containers, properly labeled, and maintain disposal documentation as required by environmental authorities.

How to transport thiourea?

Thiourea is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Use UN-approved packaging and ensure proper hazard labels are displayed. Transport vehicles must comply with ADR requirements, and drivers need appropriate training for handling Class 9 substances.

Is thiourea subject to specific regulations?

Thiourea is subject to comprehensive chemical regulations including REACH registration and CLP classification requirements in Europe. Its classification as Carc. 2 and Repr. 2 means it faces restrictions under various occupational health and safety regulations. Users must comply with workplace exposure limits, risk assessment requirements, and may need authorization for certain uses. Importers and manufacturers must fulfill REACH obligations.

Where to buy thiourea in Europe?

Thiourea is available through OYSI, a European distributor of technical chemicals. As a specialized chemical distributor, OYSI can provide thiourea with proper documentation, safety data sheets, and regulatory compliance support. Given the substance's hazardous classification, purchasing from experienced chemical distributors ensures proper handling, packaging, and regulatory compliance throughout the supply chain in European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.