Thiourea

CH4N2S

thiourea

CAS62-56-6
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
62-56-6
EC Number
200-543-5
UN Number
3077
Index Number
612-082-00-0
PubChem CID
2723790

Physical-chemical properties

Molecular Formula
CH4N2S
Molar Mass
76.12 g/mol
IUPAC Name
thiourea

Chemical Identifiers

InChI
InChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
InChI Key
UMGDCJDMYOKAJW-UHFFFAOYSA-N

Overview

Thiourea (CAS 62-56-6) is an organosulfur compound with thiocarbonyl functionality used in various industrial applications and chemical syntheses. This white crystalline solid, with the molecular formula CH4N2S and molecular weight of 76.12 g/mol, represents a fundamental building block in organic chemistry and industrial processes. Thiourea is characterized by its sulfur analog structure to urea, where the oxygen atom is replaced by sulfur, resulting in distinctive chemical properties that make it valuable across multiple industrial sectors. The compound exhibits significant safety considerations, classified under GHS pictograms GHS08, GHS07, and GHS09, with hazard classifications including carcinogenicity (Category 2), reproductive toxicity (Category 2), acute toxicity (Category 4), and chronic aquatic toxicity (Category 2). These classifications necessitate careful handling protocols and appropriate safety measures during storage, transportation, and use. The ADR Class 9 designation further emphasizes the need for specialized logistics considerations. Thiourea demonstrates excellent solubility in water and polar solvents, contributing to its versatility in various chemical processes. Its nucleophilic properties and ability to form coordination complexes with metals make it particularly valuable in industrial applications. The compound's reactivity profile differs significantly from simpler compounds like 1,4-dichlorobenzene, highlighting its specialized role in complex chemical transformations. Primary industrial applications include its use as a vulcanization accelerator in rubber production, as a flotation agent in mining operations for sulfide ore separation, and as an intermediate in pharmaceutical and agrochemical synthesis. The compound also serves as a photographic fixing agent and finds application in metal plating processes. OYSI provides technical-grade thiourea to European industrial customers, ensuring compliance with regional safety and quality standards for professional chemical applications.

Safety & Classification

Warning
Classification:

Carc. 2; Repr. 2; Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameThioharnstoff, fest
Marine PollutantNo

Frequently Asked Questions

What is thiourea?

Thiourea is an organosulfur compound with the chemical formula CH4N2S and CAS number 62-56-6. This white crystalline solid has a molecular weight of 76.12 g/mol and contains both sulfur and nitrogen atoms in its structure. It is classified as a hazardous chemical with carcinogenic and reproductive toxicity properties, requiring careful handling in industrial applications.

What are the physicochemical properties of thiourea?

Thiourea is a white crystalline solid at room temperature with high water solubility. It has a molecular formula of CH4N2S and a molecular weight of 76.12 g/mol. The compound is stable under normal conditions but can decompose when heated. It exhibits good solubility in polar solvents and has a characteristic sulfur-containing structure that influences its chemical reactivity.

What is thiourea used for?

Thiourea is primarily used in photography as a fixing agent, in textile processing as a auxiliary chemical, and in metal processing for silver and gold recovery. It serves as an intermediate in pharmaceutical synthesis and is used in rubber vulcanization processes. Additionally, thiourea finds applications in analytical chemistry as a reagent and in electroplating operations for metal surface treatment.

How to handle thiourea safely?

Thiourea handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its carcinogenic and reproductive toxicity classification. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Emergency eyewash stations and safety showers should be readily accessible in work areas.

How to store thiourea correctly?

Thiourea should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers away from strong oxidizing agents and acids. Storage areas should be equipped with appropriate containment measures and access should be restricted to trained personnel only. Regular inspection of containers for damage or deterioration is recommended.

What to do in case of contact with thiourea?

Skin contact with thiourea requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure.

How to dispose of thiourea appropriately?

Thiourea disposal must comply with local and national hazardous waste regulations due to its classification as carcinogenic and environmentally hazardous. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into drains, waterways, or soil. Small quantities should be collected in appropriate containers and labeled for hazardous waste collection. Incineration at authorized facilities may be required.

How to transport thiourea?

Thiourea is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transportation purposes. It requires appropriate UN packaging and labeling according to dangerous goods regulations. Transportation documents must include proper shipping names and hazard classifications. Vehicles should carry appropriate emergency equipment and drivers must have dangerous goods training certification for legal transport.

Is thiourea subject to specific regulations?

Thiourea is subject to REACH registration requirements and CLP classification as Carcinogenic Category 2, Reproductive Toxicity Category 2, and Acute Toxicity Category 4. It carries GHS pictograms GHS07, GHS08, and GHS09 with warning signal word. While not currently listed as a SVHC substance, its carcinogenic classification means it may be subject to authorization procedures and workplace exposure limits in various jurisdictions.

Where to buy thiourea in Europe?

Thiourea is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. As a hazardous chemical requiring proper handling expertise, thiourea should only be purchased from qualified chemical distributors who can provide appropriate safety documentation, technical support, and ensure compliance with transportation and handling regulations for professional applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.