Butan-2-amine

C4H11N

butan-2-amine

CAS13952-84-6
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
13952-84-6
EC Number
237-732-7
UN Number
2733
Index Number
612-052-00-7
PubChem CID
24874

Physical-chemical properties

Molecular Formula
C4H11N
Molar Mass
73.14 g/mol
IUPAC Name
butan-2-amine

Chemical Identifiers

InChI
InChI=1S/C4H11N/c1-3-4(2)5/h4H,3,5H2,1-2H3
InChI Key
BHRZNVHARXXAHW-UHFFFAOYSA-N

Overview

Butan-2-amine (CAS 13952-84-6) is a secondary aliphatic amine with flammable properties and corrosive characteristics requiring specialized handling protocols. This branched-chain amine compound, with the molecular formula C4H11N and a molecular weight of 73.14 g/mol, represents an important intermediate in organic synthesis and industrial chemistry. As a member of the butylamine family, butan-2-amine exhibits typical amine reactivity while presenting unique structural characteristics due to its secondary carbon attachment point. The compound is classified under EC number 237-732-7 and falls under ADR Class 3 for transportation purposes. The safety profile of butan-2-amine demands careful attention, as indicated by its GHS02, GHS07, GHS05, and GHS09 pictograms. The substance is classified as a Category 2 flammable liquid and Category 1A skin corrosive material, necessitating appropriate personal protective equipment and ventilation systems during handling. Its acute toxicity classification (Category 4) and aquatic acute toxicity properties require implementation of strict environmental protection measures and waste management protocols. Industrial applications for butan-2-amine include its use as a building block in pharmaceutical synthesis, where it serves as a precursor for various therapeutic compounds. The chemical industry utilizes this amine in the production of specialty chemicals and as an intermediate in polymer synthesis. Additionally, it finds application in the manufacture of surfactants and corrosion inhibitors, where its amine functionality provides essential chemical reactivity. Unlike more complex derivatives such as (2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone, butan-2-amine offers straightforward synthetic accessibility while maintaining versatile reactivity patterns essential for industrial processes. OYSI maintains reliable supply chains for butan-2-amine, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1A; Aquatic Acute 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2733
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameButan-2-amin, R/S-Isomere oder Isomerengemisch
Marine PollutantNo

Frequently Asked Questions

What is butan-2-amine?

Butan-2-amine is a secondary aliphatic amine with the molecular formula C4H11N and CAS number 13952-84-6. This organic compound has a molecular weight of 73.14 g/mol and belongs to the class of butylamine derivatives. It is characterized by an amino group attached to the second carbon of a butane chain, making it an isomer of other butylamine compounds. Due to its amine functional group, it exhibits basic properties and typical amine reactivity patterns in chemical processes.

What are the physicochemical properties of butan-2-amine?

Butan-2-amine is a flammable liquid at room temperature with characteristic amine odor properties. As a secondary amine with molecular formula C4H11N, it exhibits basic chemical behavior and can form salts with acids. The compound is likely miscible with polar solvents due to its amine functionality and moderate carbon chain length. Its flammable nature is reflected in its Flam. Liq. 2 classification, indicating relatively low flash point and significant fire hazard potential.

What is butan-2-amine used for?

Butan-2-amine is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its secondary amine structure makes it valuable for producing various chemical derivatives, including pharmaceuticals, agrochemicals, and specialty chemicals. The compound serves as a building block in the synthesis of more complex nitrogen-containing compounds and can be used in the production of surfactants, corrosion inhibitors, and rubber processing chemicals. Its reactivity with acids and other electrophiles makes it useful in various industrial chemical processes.

How to handle butan-2-amine safely?

Butan-2-amine requires careful handling due to its corrosive (Skin Corr. 1A) and toxic properties (Acute Tox. 4). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods due to potential inhalation hazards. Avoid ignition sources as the compound is highly flammable (Flam. Liq. 2). Emergency eyewash and shower facilities must be readily accessible when working with this corrosive substance.

How to store butan-2-amine correctly?

Butan-2-amine must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its Flam. Liq. 2 classification. Use appropriate chemical-resistant containers and ensure secondary containment to prevent spills. Store separately from acids, oxidizing agents, and incompatible materials to prevent dangerous reactions. The storage area should have appropriate fire suppression systems and be designed for flammable liquid storage. Keep containers tightly sealed to prevent vapor release and contamination.

What to do in case of contact with butan-2-amine?

Butan-2-amine contact requires immediate emergency response due to its Skin Corr. 1A classification. For skin contact, immediately flush the affected area with copious amounts of water for at least 15 minutes while removing contaminated clothing. In case of eye contact, rinse continuously with water and seek immediate medical attention. If inhaled, move the person to fresh air and provide respiratory support if needed. For ingestion, do not induce vomiting and seek immediate medical care. Always consult a physician after any exposure incident.

How to dispose of butan-2-amine properly?

Butan-2-amine disposal must comply with local and European waste regulations due to its hazardous properties and Aquatic Acute 1 classification. The substance cannot be discharged into sewers or waterways due to its environmental toxicity. Disposal should be conducted through licensed hazardous waste contractors who can handle flammable and corrosive materials. Incineration at appropriate high-temperature facilities or chemical neutralization may be suitable methods. Always consult local environmental authorities and follow the safety data sheet recommendations for proper waste management procedures.

How to transport butan-2-amine?

Butan-2-amine is classified as ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport protocols for dangerous goods. Transportation must comply with European ADR regulations using appropriate UN-specification packaging designed for flammable and corrosive substances. Vehicles must carry proper placarding, emergency response information, and trained drivers with dangerous goods certification. The transport documentation must include all required hazard information and emergency contact details. Professional logistics companies experienced in chemical transport should handle shipment to ensure regulatory compliance.

Is butan-2-amine subject to specific regulations?

Butan-2-amine is subject to multiple European chemical regulations including REACH registration requirements and CLP classification obligations. The substance is not currently listed as an SVHC (Substance of Very High Concern) under REACH. However, its hazardous properties require compliance with workplace safety regulations, environmental protection laws, and transport of dangerous goods legislation. Users must maintain safety data sheets, implement appropriate risk management measures, and ensure proper worker training. Industrial users may need to report usage under various national chemical inventory systems.

Where to buy butan-2-amine in Europe?

Butan-2-amine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides reliable supply chain management for hazardous chemicals like butan-2-amine, ensuring proper handling, documentation, and regulatory compliance throughout the distribution process. As a professional chemical distributor, OYSI offers technical support, appropriate packaging, and delivery services designed for dangerous goods transport. Contact OYSI directly for availability, specifications, and pricing information tailored to your specific industrial requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.