Butan-2-amine

C4H11N

butan-2-amine

CAS13952-84-6
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
13952-84-6
EC Number
237-732-7
UN Number
2733
Index Number
612-052-00-7
PubChem CID
24874

Physical-chemical properties

Molecular Formula
C4H11N
Molar Mass
73.14 g/mol
IUPAC Name
butan-2-amine

Chemical Identifiers

InChI
InChI=1S/C4H11N/c1-3-4(2)5/h4H,3,5H2,1-2H3
InChI Key
BHRZNVHARXXAHW-UHFFFAOYSA-N

Overview

Butan-2-amine (CAS 13952-84-6) is a primary aliphatic amine with flammable properties and corrosive characteristics. This branched-chain amine compound, with the molecular formula C4H11N and a molecular weight of 73.14 g/mol, represents an important intermediate in organic synthesis and industrial chemistry. As a secondary butylamine isomer, butan-2-amine exhibits typical amine functionality while possessing unique reactivity patterns due to its specific structural configuration. The compound is classified under multiple hazard categories, including flammable liquid category 2 and skin corrosive category 1A, requiring careful handling protocols in industrial environments. The substance presents significant safety considerations due to its corrosive nature and potential for acute toxicity through multiple exposure routes. Its flammable properties, classified under ADR class 3 for transport purposes, necessitate appropriate storage conditions away from ignition sources and oxidizing materials. The compound's aquatic toxicity classification also demands environmental protection measures during handling and disposal operations. In industrial applications, butan-2-amine serves as a valuable building block for pharmaceutical intermediates, agricultural chemicals, and specialty polymer production. The compound finds particular utility in the synthesis of various nitrogen-containing organic compounds, where its primary amine functionality enables diverse chemical transformations. Unlike more complex molecules such as (2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone, butan-2-amine offers straightforward reactivity for fundamental organic synthesis processes. Additional applications include its role in surfactant manufacturing and as a chemical intermediate in the production of corrosion inhibitors and fuel additives. OYSI maintains reliable supply chains for butan-2-amine to support diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1A; Aquatic Acute 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2733
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameButan-2-amin, R/S-Isomere oder Isomerengemisch
Marine PollutantNo

Frequently Asked Questions

What is butan-2-amine?

Butan-2-amine is a primary aliphatic amine with the molecular formula C4H11N and CAS number 13952-84-6. It is a flammable liquid with corrosive properties, belonging to the class of short-chain alkyl amines. With a molecular weight of 73.14 g/mol, this chemical compound is characterized by an amino group attached to the second carbon of a butane chain, making it an isomer of butylamine with distinct chemical and physical properties.

What are the physicochemical properties of butan-2-amine?

Butan-2-amine is a colorless liquid at room temperature with a characteristic ammonia-like odor typical of aliphatic amines. As a low molecular weight amine, it exhibits good solubility in water and polar organic solvents due to its ability to form hydrogen bonds. The compound has a boiling point in the range typical for short-chain amines and displays basic properties in aqueous solution, forming salts with acids.

What is butan-2-amine used for?

Butan-2-amine is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for the production of various chemicals including pharmaceuticals, agrochemicals, and specialty chemicals. The compound is also utilized in the synthesis of surfactants, corrosion inhibitors, and as a catalyst or catalyst precursor in certain chemical reactions. Its amine functionality makes it valuable for creating nitrogen-containing compounds in industrial processes.

How to handle butan-2-amine safely?

Butan-2-amine requires careful handling due to its flammable and corrosive nature. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. Eliminate ignition sources as the substance is classified as Flammable Liquid Category 2. Ground all equipment to prevent static electricity buildup during transfer operations.

How to store butan-2-amine correctly?

Butan-2-amine must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points. Use appropriate containers resistant to corrosive amines, typically stainless steel or suitable plastic materials. Keep containers tightly closed and avoid contact with acids, oxidizing agents, and incompatible materials. Storage areas should be equipped with appropriate fire suppression systems and emergency response equipment due to the flammable nature of the substance.

What to do in case of contact with butan-2-amine?

Butan-2-amine contact requires immediate action due to its corrosive properties. For skin contact, immediately flush with plenty of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse thoroughly with water for at least 15 minutes and seek immediate medical attention. If inhaled, move the person to fresh air and provide respiratory support if needed. For ingestion, do not induce vomiting and seek immediate medical care.

How to dispose of butan-2-amine appropriately?

Butan-2-amine disposal must comply with local and national hazardous waste regulations due to its classification as flammable and corrosive. The substance should never be discharged into sewers or waterways due to its aquatic toxicity classification. Professional hazardous waste disposal services should handle the waste through approved methods such as incineration at licensed facilities. Small quantities may require neutralization before disposal, following appropriate safety protocols and regulatory guidelines.

How to transport butan-2-amine?

Butan-2-amine is classified under ADR as Class 3 (flammable liquids), Packing Group II, indicating moderate danger level during transport. Transportation requires appropriate UN-approved packaging designed for flammable and corrosive substances. Vehicles must carry proper documentation, emergency response information, and appropriate safety equipment. Drivers require ADR training certification, and transport must follow designated routes with proper placarding and labeling according to dangerous goods regulations.

Is butan-2-amine subject to specific regulations?

Butan-2-amine is subject to various chemical regulations including REACH registration requirements for manufacture and import in the European Union. The substance must comply with CLP regulation for classification and labeling, displaying appropriate GHS pictograms (GHS02, GHS07, GHS05, GHS09) and danger signal word. While not currently listed as a SVHC substance, it may be subject to workplace exposure limits and specific handling requirements depending on national legislation and intended use.

Where to buy butan-2-amine in Europe?

Butan-2-amine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides this chemical compound with full regulatory compliance documentation and technical support. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transportation according to ADR requirements. Contact OYSI directly for availability, specifications, and regulatory documentation to meet your specific industrial application needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.