N-propylpropan-1-amine

C6H15N

CAS142-84-7
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
142-84-7
EC Number
205-565-9
UN Number
2383
Index Number
612-048-00-5
PubChem CID
8902

Physical-chemical properties

Molecular Formula
C6H15N
Molar Mass
101.19 g/mol
IUPAC Name
N-propylpropan-1-amine

Chemical Identifiers

InChI
InChI=1S/C6H15N/c1-3-5-7-6-4-2/h7H,3-6H2,1-2H3
InChI Key
WEHWNAOGRSTTBQ-UHFFFAOYSA-N

Overview

N-propylpropan-1-amine (CAS 142-84-7) is a secondary aliphatic amine with flammable and corrosive properties used in industrial chemical synthesis. This organic compound, also known by its EC number 205-565-9, belongs to the family of dialkyl amines and serves as an important intermediate in various chemical manufacturing processes. With its molecular formula C6H15N and molecular weight of 101.19 g/mol, N-propylpropan-1-amine exhibits typical characteristics of secondary amines, including strong basicity and nucleophilic reactivity. The compound shares structural similarities with other industrial amines such as butan-1-amine and N-ethylethanamine, but offers distinct reactivity profiles due to its specific alkyl chain configuration. Safety considerations are paramount when handling this substance, as it is classified under multiple hazard categories including Flammable Liquid Category 2 and Skin Corrosion Category 1A. The "Danger" signal word and associated GHS pictograms (GHS02, GHS07, GHS05) reflect its potential for causing severe skin burns, eye damage, and its flammable nature. As an ADR Class 3 substance, special transportation and storage protocols must be followed to ensure safe handling throughout the supply chain. Primary industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, as a catalyst in polymerization reactions, and in the production of specialized surfactants and corrosion inhibitors. The compound's reactivity makes it valuable in organic synthesis where selective alkylation or acylation reactions are required. OYSI provides N-propylpropan-1-amine to European industrial customers with comprehensive technical support and regulatory documentation to ensure compliant and safe usage across various applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1A

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2383
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameDipropylamin
Marine PollutantNo

Frequently Asked Questions

What is N-propylpropan-1-amine?

N-propylpropan-1-amine is a secondary aliphatic amine with the molecular formula C6H15N and CAS number 142-84-7. This organic compound has a molecular weight of 101.19 g/mol and belongs to the dipropylamine family. It is classified as a flammable liquid with corrosive properties and acute toxicity. The substance presents significant safety hazards requiring careful handling and appropriate safety measures in industrial applications.

What are the physicochemical properties of N-propylpropan-1-amine?

N-propylpropan-1-amine is typically a colorless to pale yellow liquid at room temperature with a characteristic amine odor. As a secondary amine, it exhibits basic properties and is soluble in water and most organic solvents. The compound has a relatively low molecular weight of 101.19 g/mol, contributing to its volatility. Its flammable nature (Flam. Liq. 2 classification) indicates a flash point between 23°C and 60°C, requiring careful temperature control during handling.

What is N-propylpropan-1-amine used for?

N-propylpropan-1-amine is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for producing various chemicals, including agrochemicals, surfactants, and specialty chemicals. The compound is also utilized in research and development applications, particularly in the synthesis of complex organic molecules. Its amine functionality makes it valuable for creating derivatives through alkylation, acylation, and other chemical transformations in industrial processes.

How to handle N-propylpropan-1-amine safely?

N-propylpropan-1-amine requires strict safety protocols due to its corrosive and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face shields, and acid-resistant clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Eliminate ignition sources due to its flammable nature. Avoid skin and eye contact, as the substance can cause severe burns. Emergency shower and eyewash stations should be readily accessible.

How to store N-propylpropan-1-amine correctly?

N-propylpropan-1-amine must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use appropriate chemical-resistant containers with tight-fitting lids to prevent vapor escape. Store separately from acids, oxidizing agents, and incompatible materials to prevent dangerous reactions. Maintain storage temperatures below the flash point and ensure compliance with local flammable liquid storage regulations. Secondary containment systems are recommended to manage potential spills.

What to do in case of contact with N-propylpropan-1-amine?

N-propylpropan-1-amine contact requires immediate emergency response due to its corrosive nature. For skin contact, immediately flush with copious amounts of water for at least 15 minutes while removing contaminated clothing. For eye contact, rinse continuously with water and seek immediate medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical care. Always consult a physician after any significant exposure, regardless of apparent severity.

How to dispose of N-propylpropan-1-amine appropriately?

N-propylpropan-1-amine disposal must comply with local, national, and international hazardous waste regulations due to its toxic and flammable properties. The substance cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment facilities. Waste should be collected in appropriate containers, properly labeled, and handled by licensed waste disposal companies. Neutralization or incineration at authorized facilities may be required. Consult local environmental authorities for specific disposal requirements and approved treatment methods.

How to transport N-propylpropan-1-amine?

N-propylpropan-1-amine is classified under ADR Class 3 (flammable liquids), Packing Group II, indicating moderate danger during transport. Transportation requires appropriate UN-approved packaging, proper labeling with GHS02, GHS07, and GHS05 pictograms, and compliance with dangerous goods regulations. Vehicles must carry appropriate safety equipment and documentation. Drivers require ADR certification for handling Class 3 substances. Emergency response information and safety data sheets must accompany shipments to ensure proper handling during transport incidents.

Is N-propylpropan-1-amine subject to specific regulations?

N-propylpropan-1-amine is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. While not currently listed as a Substance of Very High Concern (SVHC), it must comply with standard chemical safety requirements due to its hazardous properties. Users must maintain safety data sheets, implement appropriate risk management measures, and ensure worker protection compliance. The substance may be subject to additional sector-specific regulations depending on its intended use and application.

Where to buy N-propylpropan-1-amine in Europe?

N-propylpropan-1-amine is available through OYSI, a specialized European distributor of technical chemicals with extensive experience in handling hazardous substances. OYSI provides comprehensive support including regulatory compliance documentation, safety data sheets, and technical guidance for safe handling and storage. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transport compliance with European regulations. Contact OYSI directly for availability, specifications, and technical support for your N-propylpropan-1-amine requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.