4-methylbenzenesulfonic acid

C7H8O3S

CAS104-15-4
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
104-15-4
EC Number
203-180-0
UN Number
2585
Index Number
016-030-00-2
PubChem CID
6101

Physical-chemical properties

Molecular Formula
C7H8O3S
Molar Mass
172.20 g/mol
IUPAC Name
4-methylbenzenesulfonic acid

Chemical Identifiers

InChI
InChI=1S/C7H8O3S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H,8,9,10)
InChI Key
JOXIMZWYDAKGHI-UHFFFAOYSA-N

Overview

4-methylbenzenesulfonic acid (CAS 104-15-4) is an aromatic sulfonic acid compound with strong acidic properties and excellent solubility characteristics. 4-methylbenzenesulfonic acid, also known as para-toluenesulfonic acid or p-TSA, represents a fundamental building block in organic chemistry and industrial applications. With its molecular formula C7H8O3S and molecular weight of 172.2 g/mol, this white crystalline compound belongs to the sulfonic acid family, characterized by the presence of a sulfonic acid group (-SO3H) attached to a methylated benzene ring. The compound's structure combines the stability of an aromatic system with the reactivity of a strong acid functionality. From a safety perspective, 4-methylbenzenesulfonic acid is classified under GHS07 pictogram with a "Warning" signal word. The substance poses moderate hazards including skin irritation (Skin Irrit. 2), eye irritation (Eye Irrit. 2), and specific target organ toxicity following single exposure (STOT SE 3). Its ADR classification as Class 8 indicates its corrosive nature, requiring appropriate handling procedures and protective equipment during storage and transportation. Industrial applications of 4-methylbenzenesulfonic acid span multiple sectors, primarily serving as a catalyst in esterification and condensation reactions. The compound functions effectively as an acid catalyst in polymer synthesis and resin production. Additionally, it serves as an intermediate in the manufacture of dyes, pharmaceuticals, and specialty chemicals. Unlike simpler compounds such as nonanoic acid, p-toluenesulfonic acid offers superior catalytic performance in aromatic chemistry applications. OYSI maintains reliable supplies of high-quality 4-methylbenzenesulfonic acid to support diverse industrial requirements across European markets.

Safety & Classification

Warning
Classification:

STOT SE 3; Skin Irrit. 2; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2585
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping Name4-Methylbenzensulfonsäure, freie Schwefelsäure <= 5 %, fest
Marine PollutantNo

Frequently Asked Questions

What is 4-methylbenzenesulfonic acid?

4-methylbenzenesulfonic acid is an organic sulfonic acid compound with the molecular formula C7H8O3S and CAS number 104-15-4. This aromatic sulfonic acid has a molecular weight of 172.2 g/mol and consists of a benzene ring substituted with both a methyl group and a sulfonic acid group. It appears as a white to off-white crystalline solid and is classified as a mild irritant to skin and eyes.

What are the physicochemical properties of 4-methylbenzenesulfonic acid?

4-methylbenzenesulfonic acid is a white to light yellow crystalline solid at room temperature with good water solubility due to its sulfonic acid group. The compound has a molecular weight of 172.2 g/mol and exhibits hygroscopic properties, meaning it can absorb moisture from air. It demonstrates thermal stability under normal conditions and shows typical behavior of aromatic sulfonic acids in chemical reactions.

What is 4-methylbenzenesulfonic acid used for?

4-methylbenzenesulfonic acid is primarily used as a catalyst in organic synthesis reactions, particularly in esterification and polymerization processes. It serves as an intermediate in the production of dyes, pharmaceuticals, and specialty chemicals. The compound is also employed in electroplating solutions and as a pH regulator in various industrial applications. Its strong acidic properties make it valuable in chemical manufacturing processes.

How to handle 4-methylbenzenesulfonic acid safely?

4-methylbenzenesulfonic acid requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation of dust or vapors. Avoid direct skin and eye contact as the substance can cause irritation. Use non-sparking tools and ensure proper grounding to prevent static electricity buildup during transfer operations.

How to store 4-methylbenzenesulfonic acid correctly?

4-methylbenzenesulfonic acid should be stored in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, oxidizing agents, and metals. Keep containers tightly closed and protected from moisture due to its hygroscopic nature. Store in original labeled containers made of compatible materials and maintain storage temperatures below 25°C. Ensure storage areas are equipped with appropriate spill containment measures.

What to do in case of contact with 4-methylbenzenesulfonic acid?

In case of skin contact with 4-methylbenzenesulfonic acid, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush eyes with clean water for at least 15 minutes and seek immediate medical attention. If inhaled, move the person to fresh air and seek medical advice if respiratory irritation occurs. Always consult a physician if symptoms persist.

How to dispose of 4-methylbenzenesulfonic acid properly?

4-methylbenzenesulfonic acid must be disposed of according to local, regional, and national waste regulations as a chemical waste. Contact licensed waste disposal companies for proper treatment and disposal. The substance should not be discharged into drains, soil, or water bodies. Small quantities may be neutralized carefully with appropriate bases under controlled conditions, but this should only be done by trained personnel following proper safety protocols.

How to transport 4-methylbenzenesulfonic acid?

4-methylbenzenesulfonic acid is classified as ADR Class 8 (Corrosive substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with proper labeling including corrosive hazard markings and transport documentation. Vehicles must carry appropriate emergency equipment and drivers require ADR certification. Ensure packages are secured against movement and protected from damage during transport.

Is 4-methylbenzenesulfonic acid subject to special regulations?

4-methylbenzenesulfonic acid is regulated under the CLP Regulation with classification as STOT SE 3, Skin Irrit. 2, and Eye Irrit. 2, requiring Warning signal word and GHS07 pictogram. It falls under REACH regulation for registration and safety data sheet requirements. The substance is not listed as SVHC (Substance of Very High Concern) and has no specific use restrictions, but standard industrial chemical handling regulations apply.

Where to buy 4-methylbenzenesulfonic acid in Europe?

4-methylbenzenesulfonic acid is available through OYSI, a professional European distributor of technical chemicals serving industrial customers across Europe. OYSI provides reliable supply with proper documentation including safety data sheets and certificates of analysis. As a specialized chemical distributor, OYSI ensures compliance with European regulations and maintains quality standards for industrial applications. Contact OYSI for availability, specifications, and technical support.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.