Hydroxylamine;hydrochloride

ClH4NO

hydroxylamine;hydrochloride

CAS5470-11-1
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
5470-11-1
EC Number
226-798-2
UN Number
3260
Index Number
612-123-00-2
PubChem CID
443297

Physical-chemical properties

Molecular Formula
ClH4NO
Molar Mass
69.49 g/mol
IUPAC Name
hydroxylamine;hydrochloride

Chemical Identifiers

InChI
InChI=1S/ClH.H3NO/c;1-2/h1H;2H,1H2
InChI Key
WTDHULULXKLSOZ-UHFFFAOYSA-N

Overview

Hydroxylamine hydrochloride (CAS 5470-11-1) is an inorganic salt compound with strong reducing properties and notable corrosive characteristics. This crystalline white solid represents the hydrochloride salt form of hydroxylamine, offering enhanced stability and handling properties compared to the free base. With the molecular formula ClH4NO and a molecular weight of 69.49 g/mol, hydroxylamine hydrochloride serves as a versatile chemical intermediate in numerous industrial processes. The compound exhibits significant chemical reactivity, functioning primarily as a reducing agent and nucleophile in organic synthesis applications. Safety considerations are paramount when handling this material, as evidenced by its comprehensive hazard classification including corrosivity to metals, potential carcinogenicity, and acute toxicity concerns. The substance requires careful storage under controlled conditions to prevent degradation and ensure worker safety. Its classification under ADR Class 8 reflects its corrosive nature, necessitating specialized packaging and transport protocols. In industrial applications, hydroxylamine hydrochloride finds extensive use in pharmaceutical synthesis as a key building block for oxime formation and hydroxamic acid derivatives. The chemical industry utilizes this compound in the production of specialty chemicals and as an analytical reagent for metal analysis. Additionally, it serves important functions in polymer chemistry and textile processing applications. While structurally distinct from compounds like tributyl(tetradecyl)phosphanium tetrafluoroborate, both materials share applications in specialized chemical synthesis processes. OYSI maintains reliable supply chains for hydroxylamine hydrochloride, ensuring consistent availability for European industrial customers requiring this essential chemical intermediate.

Safety & Classification

Warning
Classification:

Met. Corr. 1; Carc. 2; Acute Tox. 4 *; Acute Tox. 4 *; STOT RE 2 *; Skin Irrit. 2; Eye Irrit. 2; ...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H290

May be corrosive to metals.

H351

Suspected of causing cancer.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3260
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameHydroxylammoniumchlorid
Marine PollutantNo

Frequently Asked Questions

What is hydroxylamine hydrochloride?

Hydroxylamine hydrochloride is a white crystalline inorganic salt with the molecular formula ClH4NO and CAS number 5470-11-1. It has a molecular weight of 69.49 g/mol and serves as the hydrochloride salt of hydroxylamine. This compound is classified as a corrosive substance with carcinogenic properties and presents multiple health hazards including acute toxicity and organ toxicity upon repeated exposure.

What are the physicochemical properties of hydroxylamine hydrochloride?

Hydroxylamine hydrochloride is a white crystalline solid that is highly soluble in water and polar solvents. The compound is hygroscopic, meaning it readily absorbs moisture from air. It has a molecular weight of 69.49 g/mol and decomposes upon heating rather than melting at a distinct temperature. The substance is odorless or has a very faint odor and forms acidic solutions when dissolved in water.

What is hydroxylamine hydrochloride used for?

Hydroxylamine hydrochloride is primarily used as a reducing agent and analytical reagent in chemical laboratories and industrial processes. It serves as an intermediate in pharmaceutical synthesis, particularly in the production of oximes and hydroxamic acids. The compound is also utilized in photography as a developer component, in textile industry for certain dyeing processes, and as a raw material for manufacturing other hydroxylamine derivatives.

How to handle hydroxylamine hydrochloride safely?

Hydroxylamine hydrochloride requires careful handling due to its corrosive and potentially carcinogenic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and never eat, drink, or smoke when handling the substance. Emergency eyewash stations and safety showers should be readily accessible.

How to store hydroxylamine hydrochloride correctly?

Hydroxylamine hydrochloride should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed to prevent moisture absorption due to its hygroscopic nature. Store separately from strong oxidizing agents, acids, and incompatible materials. The storage area should be equipped with appropriate spill containment measures and restricted to authorized personnel only due to the substance's hazardous classification.

What to do in case of contact with hydroxylamine hydrochloride?

Hydroxylamine hydrochloride contact requires immediate action due to its corrosive properties. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush eyes thoroughly with water for at least 15 minutes while holding eyelids open. If inhaled, move victim to fresh air immediately. Seek immediate medical attention for all exposure routes and bring the safety data sheet.

How to dispose of hydroxylamine hydrochloride appropriately?

Hydroxylamine hydrochloride disposal must comply with local and national hazardous waste regulations due to its classification as corrosive and potentially carcinogenic material. The substance cannot be disposed of as regular waste and requires treatment by licensed hazardous waste disposal companies. Small quantities may be neutralized following specific protocols, but this should only be done by trained personnel. Always consult local environmental authorities for specific disposal requirements.

How to transport hydroxylamine hydrochloride?

Hydroxylamine hydrochloride is classified under ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. It must be packaged in approved containers meeting UN packaging requirements and labeled with appropriate hazard labels including the corrosive pictogram. Transport documentation must include proper shipping names and hazard classifications. Only authorized carriers trained in handling corrosive materials should transport this substance, following all applicable dangerous goods regulations.

Is hydroxylamine hydrochloride subject to specific regulations?

Hydroxylamine hydrochloride is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification as a corrosive, carcinogenic substance. While not currently listed as a Substance of Very High Concern (SVHC), its Carc. 2 classification requires specific labeling and safety measures. Users must comply with occupational exposure limits, proper risk assessments, and safety data sheet provisions under applicable workplace safety regulations.

Where to buy hydroxylamine hydrochloride in Europe?

Hydroxylamine hydrochloride is available through OYSI, a specialized European distributor of technical chemicals serving industrial and professional customers across Europe. As an established chemical distributor, OYSI provides quality hydroxylamine hydrochloride with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, technical specifications, packaging options, and delivery arrangements to your specific European location.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.