N,N-diethylcarbamoyl chloride

N,N-diethylcarbamoyl chloride is an organic chemical compound with the molecular formula C5H10ClNO and CAS number 88-10-8. This carbamoyl chloride derivative has a molecular weight of 135.59 g/mol and belongs to the family of acyl chlorides. It is classified as a hazardous substance with carcinogenic properties (Category 2) and poses acute toxicity risks. The compound requires careful handling due to its corrosive nature and potential health impacts.

N,N-diethylcarbamoyl chloride is typically a liquid at room temperature with corrosive properties characteristic of acyl chlorides. As an organic chloride compound, it is likely soluble in organic solvents but reacts readily with water, releasing hydrochloric acid. The substance exhibits typical acyl chloride reactivity, being highly reactive toward nucleophiles including water, alcohols, and amines. Its corrosive nature requires appropriate containment materials resistant to chemical attack.

N,N-diethylcarbamoyl chloride is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its reactive acyl chloride functionality makes it valuable for introducing carbamoyl groups into organic molecules through nucleophilic substitution reactions. The compound serves as a building block in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals. Industrial applications include the production of carbamate derivatives and other nitrogen-containing organic compounds used in research and manufacturing.

N,N-diethylcarbamoyl chloride requires strict safety protocols due to its carcinogenic and corrosive properties. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely. Use non-sparking tools and ensure proper grounding to prevent static discharge. Emergency eyewash stations and safety showers must be readily accessible in work areas.

N,N-diethylcarbamoyl chloride must be stored in a cool, dry, well-ventilated area away from moisture and incompatible materials. Keep containers tightly closed and use chemically resistant materials for storage vessels. Store away from water, alcohols, amines, and other nucleophilic substances that can react violently with acyl chlorides. Maintain storage temperatures below ambient conditions and protect from direct sunlight. Implement appropriate fire prevention measures and ensure storage areas comply with local chemical storage regulations.

Immediate action is critical following contact with N,N-diethylcarbamoyl chloride. For skin contact, remove contaminated clothing and flush affected areas with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care. Always consult a physician after any exposure incident.

N,N-diethylcarbamoyl chloride disposal must comply with local and national hazardous waste regulations due to its carcinogenic classification. The substance cannot be disposed of through normal waste streams and requires treatment by licensed hazardous waste disposal companies. Small quantities may be neutralized carefully under controlled conditions by qualified personnel, but this should only be done following established safety protocols. Containers must be properly labeled and documented according to waste tracking requirements before collection.

N,N-diethylcarbamoyl chloride is classified under ADR as Class 8 (Corrosive substances), Packing Group III for transportation purposes. Shipments must use appropriate packaging that meets UN specification requirements for corrosive materials. Vehicles must carry proper placarding and documentation including safety data sheets. Drivers require ADR certification for handling hazardous materials. Emergency response information must accompany shipments, and transport should avoid populated areas and environmentally sensitive locations where possible.

N,N-diethylcarbamoyl chloride is subject to comprehensive chemical regulations including REACH registration requirements in the European Union and CLP classification obligations. Its carcinogenic classification (Category 2) subjects it to strict workplace exposure controls and labeling requirements. The substance requires safety data sheets compliant with current regulations and may be subject to authorization or restriction procedures. Companies handling this material must implement appropriate risk management measures and maintain compliance with occupational health and safety legislation.

N,N-diethylcarbamoyl chloride is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial and research customers with appropriate handling capabilities and regulatory compliance. As a controlled substance requiring specialized handling, purchases typically require verification of end-use applications and proper safety infrastructure. Contact OYSI directly for availability, technical specifications, and regulatory documentation required for your specific application and jurisdiction.