N,N-diethylcarbamoyl chloride

N,N-diethylcarbamoyl chloride is an organic chemical compound with the molecular formula C5H10ClNO and CAS number 88-10-8. This carbamoyl chloride derivative has a molecular weight of 135.59 g/mol and belongs to the class of acyl chlorides. It is classified as a hazardous substance with carcinogenic properties (Category 2) and causes acute toxicity, skin and eye irritation, and specific target organ toxicity.

N,N-diethylcarbamoyl chloride is typically a liquid at room temperature with a characteristic pungent odor typical of acyl chlorides. As an acyl chloride, it is highly reactive with water and alcohols, undergoing hydrolysis reactions. The compound is generally soluble in organic solvents but reacts violently with protic solvents. Its molecular structure contains a carbonyl group attached to both chlorine and a diethylamino group.

N,N-diethylcarbamoyl chloride is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as an acylating agent for introducing diethylcarbamoyl groups into molecules during chemical reactions. The compound is commonly employed in the synthesis of carbamate derivatives, pharmaceuticals, and agrochemicals. It is also used in research laboratories for specialized organic transformations and as a reagent in fine chemical production.

N,N-diethylcarbamoyl chloride requires careful handling due to its carcinogenic and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and never eat, drink, or smoke while handling. Use appropriate respiratory protection when ventilation is insufficient, and ensure emergency procedures are readily available.

N,N-diethylcarbamoyl chloride should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep away from water, alcohols, and other protic solvents as it reacts violently with these substances. Store separately from incompatible materials including bases, oxidizing agents, and reducing agents. Ensure storage areas have appropriate spill containment measures and are accessible only to trained personnel.

Skin contact with N,N-diethylcarbamoyl chloride requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move the person to fresh air immediately and seek medical help. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete emergency procedures.

N,N-diethylcarbamoyl chloride disposal must comply with local and national hazardous waste regulations due to its carcinogenic classification. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment. Contact licensed waste disposal companies for proper collection and treatment. Small quantities may be neutralized carefully under controlled conditions by trained personnel, but this should only be done following established safety protocols and regulatory requirements.

N,N-diethylcarbamoyl chloride is classified under ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. It must be packaged in approved containers meeting UN specification requirements and properly labeled with appropriate hazard placards. Transport documentation must include proper shipping names, hazard classes, and emergency response information. Only trained personnel should handle the transportation, and vehicles must comply with ADR regulations for corrosive materials.

N,N-diethylcarbamoyl chloride is subject to various European regulations including REACH registration requirements and CLP classification obligations. Its carcinogenic Category 2 classification means it falls under strict handling and labeling requirements. While not currently listed as a SVHC (Substance of Very High Concern), its hazardous properties require compliance with occupational health and safety regulations. Companies must ensure proper risk assessments, safety data sheets, and worker protection measures are implemented.

N,N-diethylcarbamoyl chloride is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to pharmaceutical, chemical manufacturing, and research industries across Europe. As a professional chemical distributor, OYSI ensures proper packaging, documentation, and regulatory compliance for this hazardous substance. Contact OYSI directly for availability, technical specifications, and delivery options to your specific European location.