4-methylbenzene-1,3-diamine

C7H10N2

CAS95-80-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
95-80-7
EC Number
202-453-1
UN Number
1709
Index Number
612-099-00-3
PubChem CID
7261

Physical-chemical properties

Molecular Formula
C7H10N2
Molar Mass
122.17 g/mol
IUPAC Name
4-methylbenzene-1,3-diamine

Chemical Identifiers

InChI
InChI=1S/C7H10N2/c1-5-2-3-6(8)4-7(5)9/h2-4H,8-9H2,1H3
InChI Key
VOZKAJLKRJDJLL-UHFFFAOYSA-N

Overview

4-methylbenzene-1,3-diamine (CAS 95-80-7) is an aromatic diamine compound with two amino groups positioned on a methylated benzene ring. This organic chemical compound, also known by its systematic IUPAC name 4-methylbenzene-1,3-diamine, represents a significant intermediate in various industrial chemical processes. With a molecular formula of C7H10N2 and molecular weight of 122.17 g/mol, this aromatic diamine features a distinctive structure where two amino groups are attached to positions 1 and 3 of a benzene ring bearing a methyl substituent at position 4. The compound belongs to the broader family of aromatic amines, sharing structural similarities with related substances such as N-methylaniline, though it differs significantly in its diamine functionality and associated properties. The safety profile of 4-methylbenzene-1,3-diamine requires careful consideration due to its classification under multiple hazard categories. The substance carries a Danger signal word and is classified as a Category 1B carcinogen, Category 2 mutagen, and Category 2 reproductive toxicant, necessitating stringent handling protocols and appropriate personal protective equipment. Additional hazard classifications include acute toxicity, skin sensitization, and specific target organ toxicity following repeated exposure. The compound also presents aquatic toxicity concerns, requiring careful environmental management during use and disposal. Industrial applications of 4-methylbenzene-1,3-diamine primarily center around its role as a chemical intermediate in the synthesis of dyes, pigments, and polymer additives. The compound serves as a crucial building block in the production of various colorants for textile and coating applications, while also finding use in the manufacture of specialty polymers and resin systems. OYSI maintains reliable supply chains for 4-methylbenzene-1,3-diamine to support diverse industrial applications across European markets.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 4 *; Acute Tox. 3 *; STOT RE 2 *; Skin Sens. 1; Aquatic Ch...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H341

Suspected of causing genetic defects.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H317

May cause an allergic skin reaction.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1709
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name2,4-Toluylendiamin, fest
Marine PollutantNo

Frequently Asked Questions

What is 4-methylbenzene-1,3-diamine?

4-methylbenzene-1,3-diamine is an aromatic organic compound with the molecular formula C7H10N2 and CAS number 95-80-7. This chemical substance features a benzene ring substituted with a methyl group and two amino groups in specific positions. With a molecular weight of 122.17 g/mol, it belongs to the diamine family of compounds and is classified as a hazardous substance due to its carcinogenic, mutagenic, and reproductive toxicity properties.

What are the physicochemical properties of 4-methylbenzene-1,3-diamine?

4-methylbenzene-1,3-diamine is an aromatic diamine compound that typically appears as a crystalline solid at room temperature. The substance contains two amino functional groups attached to a methylated benzene ring, giving it basic properties and the ability to form salts with acids. Its molecular structure allows for hydrogen bonding, affecting its solubility characteristics. The compound's aromatic nature contributes to its stability and specific chemical reactivity patterns.

What is 4-methylbenzene-1,3-diamine used for?

4-methylbenzene-1,3-diamine is primarily used as an intermediate in chemical synthesis and manufacturing processes. The compound serves as a building block for producing dyes, pigments, and other aromatic compounds due to its reactive amino groups. It may also be utilized in pharmaceutical research and development as a precursor for more complex molecules. Industrial applications typically involve its incorporation into polymer chemistry and specialty chemical production.

How to handle 4-methylbenzene-1,3-diamine safely?

4-methylbenzene-1,3-diamine requires strict safety measures due to its classification as Carcinogenic 1B, Mutagenic 2, and Acute Toxic. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely, and ensure proper training for all personnel handling this substance. Emergency procedures must be readily available.

How to store 4-methylbenzene-1,3-diamine correctly?

4-methylbenzene-1,3-diamine must be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. The storage area should be restricted to authorized personnel only due to the substance's hazardous classification. Containers should be clearly labeled with appropriate hazard warnings and kept away from oxidizing agents. Regular inspection of storage containers and maintaining proper inventory records are essential safety practices.

What to do in case of contact with 4-methylbenzene-1,3-diamine?

Immediate action is required for any contact with 4-methylbenzene-1,3-diamine due to its toxic properties. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care. Always consult emergency services for serious exposures.

How to dispose of 4-methylbenzene-1,3-diamine appropriately?

4-methylbenzene-1,3-diamine must be disposed of as hazardous waste through licensed waste management companies due to its toxic and potentially carcinogenic properties. The substance cannot be disposed of in regular waste streams or sewage systems. Disposal must comply with local and European waste regulations, including proper classification and documentation. Incineration at authorized high-temperature facilities is typically the preferred disposal method for this type of aromatic compound.

How to transport 4-methylbenzene-1,3-diamine?

4-methylbenzene-1,3-diamine is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. The substance must be packaged in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles require proper placarding and drivers need ADR certification for dangerous goods. Shipping documentation must include proper shipping names, hazard classes, and emergency response information according to international dangerous goods regulations.

Is 4-methylbenzene-1,3-diamine subject to particular regulations?

4-methylbenzene-1,3-diamine is subject to strict European regulations under REACH and CLP due to its hazardous classification as carcinogenic, mutagenic, and toxic. The substance requires safety data sheets and proper labeling with GHS pictograms GHS08, GHS06, and GHS09. Although not currently listed as SVHC, its use may be restricted in certain applications. Companies handling this substance must comply with occupational exposure limits and worker protection requirements under EU legislation.

Where to buy 4-methylbenzene-1,3-diamine in Europe?

4-methylbenzene-1,3-diamine is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI can provide this substance to qualified industrial customers with proper handling capabilities and regulatory compliance. Due to the substance's hazardous nature, purchases are restricted to professional users with appropriate safety infrastructure and trained personnel. Contact OYSI directly for availability, specifications, and regulatory documentation requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.