4-methylbenzene-1,3-diamine

C7H10N2

CAS95-80-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
95-80-7
EC Number
202-453-1
UN Number
1709
Index Number
612-099-00-3
PubChem CID
7261

Physical-chemical properties

Molecular Formula
C7H10N2
Molar Mass
122.17 g/mol
IUPAC Name
4-methylbenzene-1,3-diamine

Chemical Identifiers

InChI
InChI=1S/C7H10N2/c1-5-2-3-6(8)4-7(5)9/h2-4H,8-9H2,1H3
InChI Key
VOZKAJLKRJDJLL-UHFFFAOYSA-N

Overview

4-methylbenzene-1,3-diamine (CAS 95-80-7) is an aromatic diamine compound with two amino groups positioned meta to each other on a methylated benzene ring. This organic chemical compound, also known by its IUPAC designation 4-methylbenzene-1,3-diamine, represents a significant intermediate in industrial chemical synthesis. With the molecular formula C7H10N2 and a molecular weight of 122.17 g/mol, this aromatic diamine features a distinctive structure where two amino groups are strategically positioned at the 1 and 3 positions of a benzene ring, with an additional methyl substituent at position 4. The compound belongs to the broader family of aromatic amines, sharing structural similarities with other industrial chemicals such as N-methylaniline, though its diamine nature provides unique reactivity patterns. The substance presents considerable safety considerations, classified under multiple hazard categories including carcinogenicity (Category 1B), mutagenicity (Category 2), and reproductive toxicity (Category 2). These classifications necessitate stringent handling protocols and appropriate personal protective equipment during industrial operations. The compound exhibits acute toxicity properties and potential for skin sensitization, requiring careful risk assessment in workplace environments. Its ADR classification as Class 6.1 reflects its toxic nature during transportation and storage. Industrial applications of 4-methylbenzene-1,3-diamine primarily center on its role as a chemical intermediate in polymer synthesis, particularly in the production of specialized polyurethanes and epoxy curing agents. The compound also serves as a building block in dye manufacturing processes, where its diamine functionality enables complex chromophore formation. Additionally, it functions as an intermediate in pharmaceutical synthesis pathways. OYSI maintains reliable supply chains for 4-methylbenzene-1,3-diamine, supporting European industrial customers with consistent availability and comprehensive technical documentation for safe handling and application.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 4 *; Acute Tox. 3 *; STOT RE 2 *; Skin Sens. 1; Aquatic Ch...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H341

Suspected of causing genetic defects.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H317

May cause an allergic skin reaction.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1709
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name2,4-Toluylendiamin, fest
Marine PollutantNo

Frequently Asked Questions

What is 4-methylbenzene-1,3-diamine?

4-methylbenzene-1,3-diamine is an aromatic organic compound with the molecular formula C7H10N2 and CAS number 95-80-7. This chemical belongs to the diamine family, featuring two amino groups (-NH2) attached to a methylated benzene ring. With a molecular weight of 122.17 g/mol, it is classified as a hazardous substance with multiple health and environmental risks, including carcinogenic, mutagenic, and reproductive toxicity properties.

What are the physicochemical properties of 4-methylbenzene-1,3-diamine?

4-methylbenzene-1,3-diamine is typically a crystalline solid at room temperature with a characteristic aromatic amine odor. The compound exhibits moderate solubility in water and good solubility in organic solvents such as alcohols and ethers. Its aromatic diamine structure makes it reactive towards oxidizing agents and acids. The presence of two amino groups and a methyl substituent influences its chemical reactivity and physical properties.

What is 4-methylbenzene-1,3-diamine used for?

4-methylbenzene-1,3-diamine is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. It serves as a building block in the production of azo dyes and other colorants for textile and industrial applications. The compound is also utilized in the manufacture of polymer additives and as a precursor for various organic synthesis reactions in research and development laboratories.

How to handle 4-methylbenzene-1,3-diamine safely?

4-methylbenzene-1,3-diamine requires strict safety measures due to its hazardous classification. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely. Use non-sparking tools and ensure proper grounding to prevent static electricity buildup during handling operations.

How to store 4-methylbenzene-1,3-diamine correctly?

4-methylbenzene-1,3-diamine must be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep away from incompatible materials such as strong oxidizing agents, acids, and bases. Store in original containers with proper labeling and maintain temperatures below 25°C when possible. Ensure storage areas have appropriate spill containment measures and restricted access.

What to do in case of contact with 4-methylbenzene-1,3-diamine?

Immediate action is required for any contact with 4-methylbenzene-1,3-diamine. For skin contact, remove contaminated clothing and rinse affected area with copious amounts of water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes while holding eyelids open. Seek immediate medical attention in all cases and provide safety data sheet information to healthcare providers.

How to dispose of 4-methylbenzene-1,3-diamine appropriately?

4-methylbenzene-1,3-diamine must be disposed of as hazardous waste according to local and national regulations. Never pour down drains or dispose of with regular waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require incineration at high temperatures in specialized facilities. Always consult local environmental authorities and follow waste classification codes for proper disposal documentation.

How to transport 4-methylbenzene-1,3-diamine?

4-methylbenzene-1,3-diamine is classified under ADR Class 6.1 (toxic substances), Packing Group III for transport purposes. It requires proper hazardous goods packaging, labeling with appropriate danger diamonds, and transport documentation. Vehicles must carry appropriate emergency equipment and drivers need hazardous materials certification. Ensure packages are properly secured and marked according to international dangerous goods regulations for road transport.

Is 4-methylbenzene-1,3-diamine subject to specific regulations?

4-methylbenzene-1,3-diamine is subject to extensive European regulations including REACH registration requirements and CLP classification as Category 1B carcinogen, Category 2 mutagen, and Category 2 reproductive toxin. Although not currently listed as a Substance of Very High Concern (SVHC), its hazardous properties require compliance with occupational exposure limits, waste regulations, and transport restrictions. Companies must ensure proper risk assessments and safety measures.

Where to buy 4-methylbenzene-1,3-diamine in Europe?

4-methylbenzene-1,3-diamine is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI ensures compliance with all regulatory requirements and provides proper documentation including safety data sheets and certificates of analysis. Contact OYSI directly for availability, technical specifications, and pricing information for your specific application requirements in the European market.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.