4-(4-amino-3-chlorophenyl)-2-chloroaniline

4-(4-amino-3-chlorophenyl)-2-chloroaniline is an aromatic amine compound with the molecular formula C12H10Cl2N2 and CAS number 91-94-1. This chlorinated biphenyldiamine derivative has a molecular weight of 253.12 g/mol and is classified as a Category 1B carcinogen. It appears as a crystalline solid and belongs to the family of substituted anilines used primarily in chemical synthesis and industrial applications.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is a solid crystalline compound at room temperature with a molecular weight of 253.12 g/mol. As an aromatic amine with chlorine substituents, it typically exhibits limited water solubility but shows better solubility in organic solvents. The compound contains two amino groups and two chlorine atoms attached to a biphenyl structure, giving it specific chemical reactivity patterns typical of substituted anilines.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is primarily used as an intermediate in chemical synthesis and manufacturing processes. Its aromatic amine structure makes it valuable for producing dyes, pigments, and other organic compounds. The compound serves as a building block in pharmaceutical and agrochemical synthesis, though its use is heavily regulated due to its carcinogenic properties and requires specialized handling procedures.

4-(4-amino-3-chlorophenyl)-2-chloroaniline requires strict safety measures due to its carcinogenic and toxic properties. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Workers must wear appropriate clothing to prevent skin contact, as the compound is a skin sensitizer. Handle only in designated areas with proper engineering controls, and ensure immediate access to emergency washing facilities.

4-(4-amino-3-chlorophenyl)-2-chloroaniline must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed to prevent contamination and exposure. Due to its carcinogenic classification, storage requires restricted access with appropriate warning signs. Avoid storage near oxidizing agents, strong acids, or bases. Ensure storage areas comply with local regulations for Category 1B carcinogens.

Immediate action is critical upon contact with 4-(4-amino-3-chlorophenyl)-2-chloroaniline due to its toxic and carcinogenic nature. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with water for 15 minutes. Seek immediate medical attention in all exposure cases and provide safety data sheet information to healthcare providers.

4-(4-amino-3-chlorophenyl)-2-chloroaniline disposal must comply with hazardous waste regulations due to its carcinogenic classification and environmental hazard properties. The compound cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Contact licensed waste disposal companies experienced in handling carcinogenic materials. Ensure proper documentation and tracking throughout the disposal process according to local and EU waste regulations.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. Proper packaging must meet UN specifications and display appropriate hazard labels including GHS08, GHS07, and GHS09 pictograms. Transport documentation must include the correct shipping name, UN number, and emergency response information. Carriers must be trained in handling hazardous materials and follow ADR regulations for Class 9 substances.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is subject to extensive regulatory oversight under EU REACH and CLP regulations due to its Category 1B carcinogen classification. The compound requires registration for manufacturing or import above tonnage thresholds and may have use restrictions or authorization requirements. Users must comply with occupational exposure limits, workplace safety regulations, and environmental protection measures. Regular monitoring and reporting may be mandatory depending on usage volumes and applications.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is available through specialized chemical distributors in Europe, including OYSI, which supplies industrial chemicals to European markets. Due to its hazardous classification, purchases typically require proper licensing, end-use documentation, and compliance with regulatory requirements. Suppliers must provide safety data sheets and ensure proper packaging and transport according to ADR regulations. Contact OYSI for availability and regulatory compliance support.