4-(4-amino-3-chlorophenyl)-2-chloroaniline

4-(4-amino-3-chlorophenyl)-2-chloroaniline is an aromatic organic compound with the molecular formula C12H10Cl2N2 and CAS number 91-94-1. This dichlorinated biphenylamine derivative has a molecular weight of 253.12 g/mol and contains two amino groups and two chlorine substituents. It is classified as a Category 1B carcinogen and poses significant health and environmental risks, requiring careful handling and specialized safety measures in industrial applications.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is typically a solid crystalline compound at room temperature with a molecular weight of 253.12 g/mol. As an aromatic amine derivative, it generally exhibits limited water solubility but dissolves in organic solvents. The presence of amino groups and chlorine substituents influences its polarity and chemical reactivity. Specific physical properties like melting point and exact solubility values should be confirmed through technical data sheets.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is primarily used as an intermediate in the synthesis of dyes, pigments, and other organic compounds in the chemical industry. Its biphenylamine structure makes it valuable for producing azo dyes and other colorants. Due to its carcinogenic classification (Carc. 1B), its use is strictly regulated and limited to specialized industrial applications where appropriate safety measures and controls can be implemented.

4-(4-amino-3-chlorophenyl)-2-chloroaniline must be handled with extreme caution due to its carcinogenic properties and acute toxicity. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or fume hoods to prevent inhalation. Skin contact must be avoided at all costs, and proper decontamination procedures should be established. Only trained personnel should handle this substance.

4-(4-amino-3-chlorophenyl)-2-chloroaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas must be secured and accessible only to authorized personnel due to its carcinogenic classification. Containers should be clearly labeled with appropriate hazard warnings. Regular inspection of storage conditions and container integrity is essential to prevent leaks or degradation.

Immediate action is crucial in case of contact with 4-(4-amino-3-chlorophenyl)-2-chloroaniline. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of clean water. If inhaled, move to fresh air immediately. Seek medical attention promptly in all cases of exposure, informing medical personnel of the substance's carcinogenic properties.

4-(4-amino-3-chlorophenyl)-2-chloroaniline must be disposed of as hazardous waste through licensed waste management companies specializing in carcinogenic substances. Incineration at high temperatures in approved facilities is typically required. The substance cannot be disposed of in regular waste streams or sewage systems due to its environmental toxicity (Aquatic Acute 1, Aquatic Chronic 1). All local and national regulations for hazardous waste disposal must be strictly followed.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. It must be packaged in approved containers with proper hazard labels and documentation. Transport vehicles require appropriate placarding, and drivers must have proper training for hazardous materials. All ADR regulations for Class 9 substances must be followed, including emergency response procedures and route restrictions.

4-(4-amino-3-chlorophenyl)-2-chloroaniline is subject to strict regulations under REACH and CLP due to its carcinogenic classification (Carc. 1B). While not currently listed as an SVHC, it requires registration for manufacture or import above one tonne per year. Special authorization may be required for certain uses. Companies must implement risk management measures and provide safety data sheets. National occupational exposure limits and carcinogen handling regulations also apply.

4-(4-amino-3-chlorophenyl)-2-chloroaniline can be purchased through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. Due to its carcinogenic classification, purchase is restricted to qualified industrial users with appropriate licenses and safety infrastructure. OYSI provides technical support, proper documentation, and ensures compliance with all relevant European regulations for the safe supply of this controlled substance to authorized customers.