Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate

C14H18N4O3

methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate

CAS17804-35-2
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
17804-35-2
UN Number
3077
Index Number
613-049-00-3
PubChem CID
28780

Physical-chemical properties

Molecular Formula
C14H18N4O3
Molar Mass
290.32 g/mol
IUPAC Name
methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate

Chemical Identifiers

InChI
InChI=1S/C14H18N4O3/c1-3-4-9-15-13(19)18-11-8-6-5-7-10(11)16-12(18)17-14(20)21-2/h5-8H,3-4,9H2,1-2H3,(H,15,19)(H,16,17,20)
InChI Key
RIOXQFHNBCKOKP-UHFFFAOYSA-N

Overview

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate (CAS 17804-35-2) is a benzimidazole carbamate compound with potent systemic biological activity and notable environmental persistence. This specialized organic compound belongs to the benzimidazole carbamate family, characterized by its distinctive dual carbamate functionality and fused benzimidazole ring system. With a molecular formula of C14H18N4O3 and molecular weight of 290.32 g/mol, this substance exhibits significant biological activity that makes it valuable in various industrial applications while requiring careful handling protocols. The compound presents substantial safety considerations, classified under multiple hazard categories including mutagenic (Category 1B) and reproductive toxicity (Category 1B) properties. It also demonstrates skin irritation potential, sensitization effects, and specific target organ toxicity. Environmental impact assessments indicate high aquatic toxicity with both acute and chronic effects, necessitating stringent containment measures during use and disposal. The substance carries the "Danger" signal word with corresponding GHS08, GHS07, and GHS09 pictograms, reflecting its serious health and environmental hazards. Primary industrial applications include specialized pharmaceutical intermediates, advanced materials synthesis, and selective biological research applications. Unlike simpler compounds such as cobalt(2+) sulfate which serves broader industrial purposes, this benzimidazole derivative offers highly specific functionality in targeted chemical processes. Its unique molecular structure provides distinct advantages in applications requiring precise biological activity modulation. The compound requires Class 9 transportation classification under ADR regulations, emphasizing the need for specialized logistics and storage infrastructure. Professional handling protocols, appropriate personal protective equipment, and comprehensive risk assessment procedures are essential for safe industrial use. OYSI provides this technical-grade compound with complete regulatory documentation and safety data sheets to qualified industrial customers across Europe.

Safety & Classification

Danger
Classification:

Muta. 1B; Repr. 1B; STOT SE 3; Skin Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H340

May cause genetic defects.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameBenomyl (ISO)
Marine PollutantNo

Frequently Asked Questions

What is methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate is a benzimidazole carbamate compound with CAS number 17804-35-2 and molecular formula C14H18N4O3. This organic substance has a molecular weight of 290.32 g/mol and belongs to the carbamate family. It is classified as a hazardous chemical with multiple health and environmental concerns, requiring careful handling and appropriate safety measures in industrial applications.

What are the physicochemical properties of methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate is a solid organic compound with a molecular weight of 290.32 g/mol. The substance contains benzimidazole and carbamate functional groups, which influence its chemical behavior and solubility characteristics. As a carbamate derivative, it typically exhibits moderate stability under normal conditions but may be sensitive to extreme pH and temperature conditions. Specific physical properties such as melting point and solubility require laboratory analysis.

What is methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate used for?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate is primarily used in specialized industrial applications requiring benzimidazole carbamate chemistry. Its specific molecular structure makes it suitable for pharmaceutical intermediates, agrochemical synthesis, or specialized chemical manufacturing processes. The compound's unique benzimidazole framework combined with carbamate functionality provides specific reactivity patterns valuable in organic synthesis and chemical research applications requiring these particular structural features.

How to handle methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate safely?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate requires strict safety protocols due to its mutagenic, reproductive toxicity, and skin sensitization properties. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid skin contact and inhalation. The substance carries GHS08, GHS07, and GHS09 pictograms indicating serious health and environmental hazards requiring professional handling expertise.

How to store methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate correctly?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas should be secured and accessible only to trained personnel due to the substance's mutagenic and reproductive toxicity properties. Containers should be properly labeled with appropriate hazard warnings. Regular inspection of storage containers is essential to prevent leaks or contamination, particularly given its aquatic toxicity classification.

What to do in case of contact with methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate?

Immediate medical attention is required for any exposure to methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate due to its serious health hazards. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical care. For eye contact, flush with clean water continuously and get immediate medical attention. Do not induce vomiting if ingested. Contact emergency services and provide the safety data sheet to medical personnel.

How to dispose of methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate appropriately?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate requires disposal as hazardous waste through licensed waste management companies due to its mutagenic, reproductive, and aquatic toxicity properties. The substance cannot be disposed of in regular waste streams or sewage systems. Disposal must comply with local, national, and EU waste regulations including the Waste Framework Directive. Empty containers must also be treated as hazardous waste. Documentation and waste tracking requirements must be followed throughout the disposal process.

How to transport methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to ADR regulations. Transport must be conducted by qualified carriers with appropriate training and equipment. Packages must display proper shipping names, UN numbers, and hazard labels. Emergency response information must accompany shipments, and drivers must possess ADR certification for Class 9 materials.

Is methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate subject to specific regulations?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate is subject to multiple European regulations including REACH registration requirements and CLP classification as Muta. 1B, Repr. 1B, and other hazard categories. While not currently listed as a Substance of Very High Concern (SVHC), its mutagenic and reproductive toxicity properties may trigger authorization requirements. Users must comply with occupational exposure limits, environmental discharge restrictions, and worker protection regulations. Industrial users may require specific permits and safety assessments.

Where to buy methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate in Europe?

Methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this specialized benzimidazole carbamate compound to qualified industrial customers across Europe with appropriate handling capabilities and regulatory compliance. Due to the substance's hazardous properties and regulatory requirements, purchases are restricted to professional users with demonstrated expertise in handling mutagenic and reproductive toxicants. Contact OYSI directly for availability and technical specifications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.