2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone;hydrochloride

2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone;hydrochloride is an organic compound with CAS number 70918-74-0 and molecular formula C13H17ClN2O3. This substance has a molecular weight of 284.74 g/mol and contains both benzodioxin and piperazine structural moieties in its hydrochloride salt form. It belongs to the class of heterocyclic compounds and presents significant toxicological hazards requiring careful handling procedures.

The compound is a solid crystalline material at room temperature with a molecular weight of 284.74 g/mol. As a hydrochloride salt, it typically exhibits good water solubility and hygroscopic properties. The substance contains nitrogen and oxygen heteroatoms within its benzodioxin and piperazine ring systems, contributing to its polar characteristics. Specific physical properties such as melting point and exact solubility data should be verified through analytical certificates.

This compound is primarily used as a research chemical and pharmaceutical intermediate in drug development processes. Its benzodioxin-piperazine structure makes it valuable for medicinal chemistry applications, particularly in the synthesis of potential therapeutic agents. It serves as a building block for more complex pharmaceutical molecules and is utilized in academic and industrial research laboratories for structure-activity relationship studies and chemical synthesis projects.

Safe handling requires wearing appropriate personal protective equipment including nitrile gloves, safety goggles, and laboratory coats due to its Acute Tox. 3 classification. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure no eating, drinking, or smoking in work areas. Emergency eyewash stations and safety showers should be readily accessible during handling operations.

The compound should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers protected from light and moisture due to the hydrochloride salt form's potential hygroscopic nature. Storage areas must be equipped with appropriate safety measures including spill control materials and restricted access. Maintain storage temperatures according to manufacturer specifications and regularly inspect containers for integrity.

Immediate decontamination is essential following any exposure incident. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. Seek medical attention promptly for all exposure incidents, especially given the substance's acute toxicity classification.

Disposal must comply with local, national, and EU waste regulations due to its hazardous classification. The substance requires treatment as hazardous chemical waste and cannot be disposed of through normal laboratory drains or municipal waste systems. Contact licensed hazardous waste disposal companies for proper collection and treatment. Maintain detailed waste disposal records and ensure containers are properly labeled with waste codes and hazard information before disposal.

Transportation falls under ADR Class 6.1 (Toxic substances), Packing Group III regulations. Packages must bear appropriate UN hazard labels and markings according to dangerous goods transport requirements. Use approved packaging specifications for Class 6.1 materials and ensure proper documentation including transport documents and emergency response information. Only trained personnel should handle transportation arrangements, and carriers must be certified for dangerous goods transport.

The substance is subject to EU REACH registration requirements and CLP classification regulations showing GHS06, GHS08, and GHS09 pictograms with 'Danger' signal word. It is not currently listed as a Substance of Very High Concern (SVHC). Compliance with occupational exposure limits, waste management directives, and transport regulations is mandatory. Users must maintain safety data sheets and ensure proper risk assessments are conducted before use.

OYSI is a reliable European distributor offering this specialized chemical compound to qualified industrial and research customers. As an established chemical distributor, OYSI ensures regulatory compliance and proper documentation for hazardous substances. Contact OYSI directly for availability, specifications, and ordering information. All purchases require proper end-use documentation and compliance with applicable regulations governing the distribution of toxic substances within the European market.