3,5-dibromo-4-hydroxybenzonitrile

3,5-dibromo-4-hydroxybenzonitrile is an organobrominated chemical compound with the molecular formula C7H3Br2NO and CAS number 1689-84-5. This substance features a benzene ring substituted with two bromine atoms, one hydroxyl group, and one nitrile group. With a molecular weight of 276.91 g/mol, it belongs to the class of halogenated aromatic compounds and is classified as hazardous due to its toxicity and environmental impact.

3,5-dibromo-4-hydroxybenzonitrile is typically a solid crystalline compound at room temperature due to its aromatic structure and halogen substitutions. The presence of bromine atoms increases the molecular weight and density compared to non-halogenated analogs. The hydroxyl group provides some polarity to the molecule, while the nitrile group contributes to its chemical reactivity. Specific physical parameters like melting point and solubility depend on purity and measurement conditions.

3,5-dibromo-4-hydroxybenzonitrile is primarily used as an intermediate in pharmaceutical synthesis and organic chemistry research. Its brominated aromatic structure makes it valuable for developing active pharmaceutical ingredients through various coupling reactions. The compound also serves as a building block in agrochemical synthesis and specialty chemical manufacturing. Due to its hazardous classification, its use is restricted to professional industrial applications with appropriate safety measures.

3,5-dibromo-4-hydroxybenzonitrile requires strict safety protocols due to its Acute Toxicity 2-3 classification and skin sensitization properties. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Emergency washing facilities must be readily accessible, and only trained personnel should handle this substance in controlled professional environments.

3,5-dibromo-4-hydroxybenzonitrile must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas should be secured and accessible only to authorized personnel due to its hazardous classification. The containers should be properly labeled with GHS pictograms (GHS06, GHS08, GHS09) and hazard information. Regular inspection of storage conditions and container integrity is essential to prevent leaks or degradation.

Immediate action is required due to the acute toxicity of 3,5-dibromo-4-hydroxybenzonitrile. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of eye contact, rinse immediately with clean water for at least 15 minutes. If inhaled, move person to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention immediately. Always consult the safety data sheet and contact poison control or emergency services when exposure occurs.

3,5-dibromo-4-hydroxybenzonitrile disposal must comply with local and European waste regulations due to its hazardous classification. The substance cannot be disposed of as regular waste and requires treatment as hazardous chemical waste. Contact authorized waste management companies specializing in hazardous materials for proper disposal. Containers must be properly labeled and documented throughout the disposal process. Incineration at licensed facilities under controlled conditions is typically the preferred disposal method for such organic compounds.

3,5-dibromo-4-hydroxybenzonitrile is classified as ADR Class 6.1 (toxic substances), Packing Group II, requiring strict transport regulations compliance. Packages must be properly labeled with hazard symbols and shipping documentation must include all required safety information. Only authorized carriers trained in hazardous materials transport can handle shipments. Vehicles must carry appropriate emergency equipment and spill containment materials. Transport containers must meet UN specification standards for toxic substances.

3,5-dibromo-4-hydroxybenzonitrile is subject to European REACH and CLP regulations due to its hazardous classification. While not currently listed as SVHC (Substance of Very High Concern), its reproductive toxicity (Repr. 2) and acute toxicity classifications require compliance with strict handling, labeling, and safety data sheet requirements. Companies using this substance must ensure proper risk assessments, worker protection measures, and environmental safeguards are implemented according to European chemical safety legislation.

3,5-dibromo-4-hydroxybenzonitrile is available through OYSI, a specialized European distributor of chemical products. As a professional chemical supplier, OYSI ensures compliance with European regulations including proper documentation, safety data sheets, and transport requirements. The compound is restricted to professional use only due to its hazardous classification. Customers must demonstrate legitimate industrial or research purposes and appropriate safety handling capabilities when requesting quotations for this controlled substance.