3,5-dibromo-4-hydroxybenzonitrile

3,5-dibromo-4-hydroxybenzonitrile is an organobromine compound with the molecular formula C7H3Br2NO and CAS number 1689-84-5. This chemical features a benzene ring substituted with two bromine atoms, one hydroxyl group, and one nitrile group. With a molecular weight of 276.91 g/mol, it belongs to the category of halogenated aromatic compounds and is classified as a hazardous substance requiring careful handling due to its toxicological properties.

3,5-dibromo-4-hydroxybenzonitrile is typically a solid crystalline compound at room temperature. As a halogenated aromatic compound, it exhibits limited water solubility due to its hydrophobic bromine substituents, though the hydroxyl group provides some polar character. The compound's physical appearance and specific properties like melting point, boiling point, and solubility parameters should be confirmed through technical documentation, as these can vary depending on purity and crystalline form.

3,5-dibromo-4-hydroxybenzonitrile serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. Its unique substitution pattern makes it valuable for developing bioactive compounds and specialty chemicals. The compound is commonly used in research and development applications, particularly in medicinal chemistry for synthesizing complex molecules. Industrial applications may include its use as a building block for agrochemicals, dyes, or other fine chemicals requiring specific halogenated aromatic structures.

3,5-dibromo-4-hydroxybenzonitrile requires strict safety measures due to its Acute Tox. 2/3 and Skin Sens. 1 classifications. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. The compound's reproductive toxicity (Repr. 2) necessitates additional precautions for pregnant workers or those planning pregnancy.

3,5-dibromo-4-hydroxybenzonitrile should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and protected from light and moisture to prevent degradation. Storage areas must be equipped with appropriate containment systems and emergency response equipment. Due to its hazard classification, storage should comply with local chemical storage regulations and be segregated from oxidizing agents, strong bases, and other incompatible substances.

Immediate action is critical following exposure to 3,5-dibromo-4-hydroxybenzonitrile due to its high acute toxicity. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. For eye contact, flush with water for 15 minutes. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures.

3,5-dibromo-4-hydroxybenzonitrile disposal must comply with local and national hazardous waste regulations due to its toxic and environmentally hazardous properties (Aquatic Acute 1, Aquatic Chronic 1). The compound should never be disposed of down drains or in regular waste. Arrange disposal through licensed hazardous waste contractors who can ensure proper treatment, typically involving high-temperature incineration at authorized facilities. Maintain proper documentation throughout the disposal process as required by regulatory authorities.

3,5-dibromo-4-hydroxybenzonitrile is classified under ADR Class 6.1 (toxic substances), Packing Group II, indicating significant transport restrictions. Transportation requires appropriate UN-approved packaging, proper labeling with toxic hazard symbols, and accompanying transport documentation. Vehicles must carry emergency response information and appropriate safety equipment. Only trained personnel should handle the transport, and specific routing restrictions may apply. Compliance with international dangerous goods regulations (ADR/RID for road/rail, IMDG for sea, IATA for air) is mandatory.

3,5-dibromo-4-hydroxybenzonitrile is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. While not currently listed as a SVHC (Substance of Very High Concern), its reproductive toxicity and environmental hazard classifications trigger various regulatory obligations. Companies must ensure proper registration, classification, labeling, and safety data sheet provision. Additional restrictions may apply in specific applications, and users should monitor regulatory updates for potential future restrictions or authorizations.

OYSI is a reliable European distributor offering 3,5-dibromo-4-hydroxybenzonitrile to qualified industrial and research customers. As a specialized chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance throughout the supply chain. The company provides comprehensive technical support, safety data sheets, and certificates of analysis. Given the substance's hazardous classification, OYSI works only with customers demonstrating appropriate handling capabilities and regulatory compliance for safe use of this chemical.