Zinc bis(1-oxidopyridin-1-ium-2-thiolate)

C10H8N2O2S2Zn

zinc bis(1-oxidopyridin-1-ium-2-thiolate)

CAS13463-41-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
13463-41-7
EC Number
236-671-3
UN Number
2811
Index Number
613-333-00-7
PubChem CID
26041

Physical-chemical properties

Molecular Formula
C10H8N2O2S2Zn
Molar Mass
317.70 g/mol
IUPAC Name
zinc bis(1-oxidopyridin-1-ium-2-thiolate)

Chemical Identifiers

InChI
InChI=1S/2C5H5NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4,8H;/q;;+2/p-2
InChI Key
OTPSWLRZXRHDNX-UHFFFAOYSA-L

Overview

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) (CAS 13463-41-7) is an organometallic zinc complex with potent antimicrobial properties and significant biological activity. This specialized zinc coordination compound, also known by its EC number 236-671-3, represents a unique class of organometallic substances where zinc is chelated with two pyridine N-oxide thiolate ligands. With a molecular formula of C10H8N2O2S2Zn and molecular weight of 317.7 g/mol, this compound demonstrates the sophisticated chemistry possible when combining transition metals with heterocyclic organic ligands. The compound exhibits significant biological activity, which places it in the reproductive toxicity category 1B and acute toxicity categories 2 and 3, requiring careful handling protocols. Its classification under STOT RE 1 indicates potential for serious organ damage through repeated exposure, while the Eye Dam. 1 classification warns of severe ocular hazards. The aquatic toxicity classifications (Aquatic Acute 1 and Chronic 1) reflect its environmental impact potential, necessitating proper disposal and containment measures. Safety considerations are paramount when working with this substance, as indicated by the GHS08, GHS06, GHS05, and GHS09 pictograms and "Danger" signal word. Transport regulations classify it under ADR class 6.1, emphasizing its toxic nature. Unlike simpler antimicrobial agents such as 2,2-dibromo-2-cyanoacetamide, this zinc complex offers unique coordination chemistry properties. Primary industrial applications include specialized antimicrobial formulations, advanced material preservation systems, and research applications in coordination chemistry. The compound's dual sulfur-nitrogen coordination environment makes it particularly effective in applications requiring sustained metal ion release. OYSI maintains technical-grade zinc bis(1-oxidopyridin-1-ium-2-thiolate) inventory to support European industrial and research requirements.

Safety & Classification

Danger
Classification:

Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H301

Toxic if swallowed.

H372

Causes damage to organs through prolonged or repeated exposure.

H318

Causes serious eye damage.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameZink-Pyrithion
Marine PollutantNo

Frequently Asked Questions

What is zinc bis(1-oxidopyridin-1-ium-2-thiolate)?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) is an organometallic compound with the molecular formula C10H8N2O2S2Zn and CAS number 13463-41-7. This zinc-containing chemical has a molecular weight of 317.7 g/mol and belongs to the pyrithione family of compounds. It is classified as a highly hazardous substance with multiple danger classifications including reproductive toxicity, acute toxicity, and environmental hazards, requiring careful handling and specialized safety measures.

What are the physicochemical properties of zinc bis(1-oxidopyridin-1-ium-2-thiolate)?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) is a solid organometallic compound with a molecular weight of 317.7 g/mol. As a zinc coordination complex containing pyrithione ligands, it typically appears as a crystalline powder. The compound contains sulfur and nitrogen heteroatoms coordinated to the central zinc ion, giving it specific chemical reactivity. Its exact physical properties such as melting point, solubility, and color may vary depending on the specific crystalline form and purity grade.

What is zinc bis(1-oxidopyridin-1-ium-2-thiolate) used for?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) is primarily used as an antimicrobial and antifungal agent in various industrial applications. It serves as an active ingredient in specialized coatings, paints, and surface treatments where microbial control is essential. The compound is also utilized in research and development applications, particularly in studies involving zinc coordination chemistry and antimicrobial formulations. Its biocidal properties make it valuable for professional use in controlled industrial environments.

How to handle zinc bis(1-oxidopyridin-1-ium-2-thiolate) safely?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) requires extreme caution due to its classification as Acute Tox. 2, Acute Tox. 3, and Eye Dam. 1. Essential PPE includes chemical-resistant gloves, safety goggles with full face protection, and respiratory protection to prevent inhalation. Work in well-ventilated areas or under fume extraction systems. Avoid skin and eye contact completely. Due to its reproductive toxicity (Repr. 1B), pregnant workers should not handle this substance. Always follow COSHH assessments and workplace exposure limits.

How to store zinc bis(1-oxidopyridin-1-ium-2-thiolate) correctly?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) must be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Given its hazardous classification, storage should be in designated areas with restricted access, proper labeling, and secondary containment. Keep away from oxidizing agents and materials that could react with organometallic compounds. Ensure storage areas have appropriate spill containment measures and emergency response equipment readily available.

What to do in case of contact with zinc bis(1-oxidopyridin-1-ium-2-thiolate)?

Immediate first aid for zinc bis(1-oxidopyridin-1-ium-2-thiolate) exposure requires prompt action. For skin contact, remove contaminated clothing and wash affected area with plenty of water for at least 15 minutes. For eye contact, flush immediately with water for 15-20 minutes and seek immediate medical attention due to Eye Dam. 1 classification. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always seek professional medical advice and provide safety data sheet to medical personnel.

How to dispose of zinc bis(1-oxidopyridin-1-ium-2-thiolate) appropriately?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) requires disposal as hazardous waste through licensed waste management contractors due to its toxic and environmentally hazardous properties. The compound is classified as Aquatic Acute 1 and Aquatic Chronic 1, making it extremely harmful to aquatic environments. Never dispose of via regular waste streams or sewage systems. Packaging must be treated as contaminated waste. Follow local and national regulations for hazardous waste disposal, including proper documentation and manifesting procedures.

How to transport zinc bis(1-oxidopyridin-1-ium-2-thiolate)?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) is classified under ADR Class 6.1 (Toxic substances), Packing Group II, indicating significant toxicity requiring special transport precautions. Transportation must comply with dangerous goods regulations including proper packaging, labeling with GHS pictograms (GHS08, GHS06, GHS05, GHS09), and documentation. Only qualified carriers with appropriate permits should transport this material. Packages must be secured against movement and protected from damage during transit. Emergency response information must accompany shipments.

Is zinc bis(1-oxidopyridin-1-ium-2-thiolate) subject to specific regulations?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) is subject to comprehensive regulatory oversight under REACH and CLP regulations in Europe. While not currently listed as an SVHC substance, its multiple hazard classifications including reproductive toxicity (Repr. 1B) and high acute toxicity require strict compliance with occupational health and safety regulations. Users must maintain safety data sheets, conduct risk assessments, and implement appropriate control measures. The substance may be subject to additional restrictions depending on specific applications and local regulations.

Where to buy zinc bis(1-oxidopyridin-1-ium-2-thiolate) in Europe?

Zinc bis(1-oxidopyridin-1-ium-2-thiolate) is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI can provide this highly regulated substance to qualified industrial customers with appropriate handling capabilities and regulatory compliance. Due to the substance's hazardous classification and transport requirements under ADR Class 6.1, procurement requires proper documentation, safety assessments, and adherence to professional handling standards. Contact OYSI directly for availability and technical specifications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.