2,4,5-trichlorophenol
C6H3Cl3O
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Identification
- CAS Number
- 95-95-4
- EC Number
- 202-467-8
- UN Number
- 2020
- Index Number
- 604-017-00-X
- PubChem CID
- 7271
Physical-chemical properties
- Molecular Formula
- C6H3Cl3O
- Molar Mass
- 197.40 g/mol
- IUPAC Name
- 2,4,5-trichlorophenol
Chemical Identifiers
- InChI
- InChI=1S/C6H3Cl3O/c7-3-1-5(9)6(10)2-4(3)8/h1-2,10H
- InChI Key
- LHJGJYXLEPZJPM-UHFFFAOYSA-N
Overview
2,4,5-trichlorophenol (CAS 95-95-4) is a chlorinated phenolic compound with antimicrobial properties and environmental persistence concerns. This halogenated aromatic compound represents one of the key intermediates in chlorinated phenol chemistry, featuring three chlorine substituents at positions 2, 4, and 5 on the benzene ring. With the molecular formula C6H3Cl3O and a molecular weight of 197.4 g/mol, 2,4,5-trichlorophenol exhibits the characteristic properties of chlorinated phenols, including enhanced chemical stability and biocidal activity compared to unsubstituted phenol. The compound's safety profile requires careful handling protocols, as indicated by its GHS07 and GHS09 pictograms and Warning signal word. It presents acute toxicity concerns (Category 4), along with skin and eye irritation potential. Particularly notable are its aquatic toxicity classifications (Acute 1 and Chronic 1), reflecting its environmental impact potential and the need for responsible disposal practices. Transportation falls under ADR Class 6.1, designating it as a toxic substance requiring specialized handling during shipping and storage. Industrial applications of 2,4,5-trichlorophenol primarily include its use as a chemical intermediate in the synthesis of herbicides and other agrochemicals, as well as in the production of antimicrobial agents and wood preservatives. Its structural relationship to compounds like copper sulfate in antimicrobial applications demonstrates its role in biocide formulations. The compound also serves as a precursor in the manufacture of specialized polymers and resins where chlorinated aromatic structures provide enhanced flame retardancy and chemical resistance. OYSI maintains reliable supply chains for 2,4,5-trichlorophenol to support European industrial customers requiring this specialized chlorinated intermediate for their manufacturing processes.
Safety & Classification
Acute Tox. 4 *; Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2020 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 2,4,5-Trichlorphenol, fest, frei von TCDD |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2,4,5-trichlorophenol?
2,4,5-trichlorophenol is an organochlorine compound with the molecular formula C6H3Cl3O and CAS number 95-95-4. This chlorinated phenol derivative has a molecular weight of 197.4 g/mol and consists of a benzene ring substituted with three chlorine atoms at positions 2, 4, and 5, plus one hydroxyl group. It is classified as a hazardous chemical requiring proper handling and storage procedures due to its toxicity and environmental impact.
What are the physicochemical properties of 2,4,5-trichlorophenol?
2,4,5-trichlorophenol is typically a white to pale yellow crystalline solid at room temperature with a characteristic phenolic odor. It has limited water solubility but dissolves well in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The compound exhibits acidic properties due to its phenolic hydroxyl group and has relatively high stability under normal conditions, though it may decompose under extreme heat or alkaline conditions.
What is 2,4,5-trichlorophenol used for?
2,4,5-trichlorophenol is primarily used as an intermediate in the synthesis of other chemicals, including pesticides, herbicides, and fungicides. It serves as a precursor in pharmaceutical manufacturing and can be utilized in the production of specialized polymers and resins. The compound also finds applications in research and analytical chemistry as a reference standard. Its antimicrobial properties make it useful in certain industrial preservation applications.
How to handle 2,4,5-trichlorophenol safely?
2,4,5-trichlorophenol requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume extraction to avoid inhalation exposure. The compound is classified as Acute Tox. 4, Skin Irrit. 2, and Eye Irrit. 2, requiring adherence to safety protocols and emergency procedures to minimize health risks.
How to store 2,4,5-trichlorophenol correctly?
2,4,5-trichlorophenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Keep containers upright and properly labeled according to GHS requirements with Warning signal word and appropriate pictograms (GHS07, GHS09). Store separately from strong bases, oxidizing agents, and reactive metals. Ensure storage area has appropriate spill containment and fire protection measures.
What to do in case of contact with 2,4,5-trichlorophenol?
In case of skin contact with 2,4,5-trichlorophenol, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist or worsen.
How to dispose of 2,4,5-trichlorophenol appropriately?
2,4,5-trichlorophenol must be disposed of as hazardous waste through licensed waste management companies in compliance with local, national, and EU regulations. Due to its classification as Aquatic Acute 1 and Aquatic Chronic 1, it requires special handling to prevent environmental contamination. Contact authorized waste disposal facilities for proper collection and treatment. Never dispose of this substance through regular waste streams or discharge into sewers or water bodies.
How to transport 2,4,5-trichlorophenol?
2,4,5-trichlorophenol is classified under ADR as Class 6.1 (toxic substances), Packing Group III, requiring compliance with dangerous goods transportation regulations. Packages must be properly labeled, marked, and documented with appropriate shipping papers. Transport vehicles must carry emergency equipment and drivers need ADR certification. Ensure containers are leak-proof, properly secured, and segregated from incompatible materials during transport across European borders.
Is 2,4,5-trichlorophenol subject to specific regulations?
2,4,5-trichlorophenol is regulated under EU REACH and CLP regulations, requiring registration, classification, and labeling compliance. While not currently listed as an SVHC (Substance of Very High Concern), it must be handled according to its hazard classification with Warning signal word and GHS pictograms. Companies must maintain safety data sheets, implement risk management measures, and comply with notification requirements for industrial use and distribution.
Where to buy 2,4,5-trichlorophenol in Europe?
2,4,5-trichlorophenol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides high-quality chemical products with full regulatory compliance, proper documentation, and technical support. As a professional chemical supplier, OYSI ensures appropriate packaging, labeling, and delivery of hazardous materials according to ADR and EU regulations for industrial applications and research purposes.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.