1,2,4-trichlorobenzene
C6H3Cl3
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Identification
- CAS Number
- 120-82-1
- EC Number
- 204-428-0
- UN Number
- 2321
- Index Number
- 602-087-00-6
- PubChem CID
- 13
Physical-chemical properties
- Molecular Formula
- C6H3Cl3
- Molar Mass
- 181.40 g/mol
- IUPAC Name
- 1,2,4-trichlorobenzene
Chemical Identifiers
- InChI
- InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H
- InChI Key
- PBKONEOXTCPAFI-UHFFFAOYSA-N
Overview
1,2,4-Trichlorobenzene (CAS 120-82-1) is a chlorinated aromatic hydrocarbon with three chlorine atoms attached to a benzene ring in specific positions. This organic compound represents one of the three possible trichlorobenzene isomers and serves as an important industrial intermediate in chemical manufacturing processes. With its molecular formula C6H3Cl3 and molecular weight of 181.4 g/mol, 1,2,4-trichlorobenzene exhibits the characteristic properties of chlorinated benzenes, including chemical stability and low water solubility. The compound appears as a colorless to pale yellow liquid with a distinctive aromatic odor. From a safety perspective, 1,2,4-trichlorobenzene requires careful handling due to its classification as Acute Tox. 4 and Skin Irrit. 2 under GHS regulations. The substance carries Warning signal words and displays GHS07 and GHS09 pictograms, indicating both health hazards and environmental concerns. Its classification as Aquatic Acute 1 and Aquatic Chronic 1 reflects significant environmental toxicity, particularly to aquatic organisms. Transportation regulations classify it under ADR Class 6.1, emphasizing the need for proper handling protocols during shipping and storage. Industrial applications of 1,2,4-trichlorobenzene include its use as a solvent for various chemical processes, as an intermediate in the synthesis of pesticides and herbicides, and in the production of specialty chemicals. The compound shares chemical similarities with related chlorinated aromatics such as 4-bromo-2-chloro-1-fluorobenzene, which also finds applications in pharmaceutical and agrochemical synthesis. OYSI provides reliable access to 1,2,4-trichlorobenzene for qualified industrial customers throughout Europe, ensuring compliance with all relevant safety and transportation regulations.
Safety & Classification
Acute Tox. 4 *; Skin Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2321 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 1,2,4-Trichlorbenzen, flüssig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1,2,4-trichlorobenzene?
1,2,4-trichlorobenzene is an organochlorine compound with the molecular formula C6H3Cl3 and CAS number 120-82-1. It belongs to the family of chlorinated benzenes, featuring three chlorine atoms attached to a benzene ring at positions 1, 2, and 4. With a molecular weight of 181.4 g/mol, this chemical compound is classified as hazardous with acute toxicity and environmental concerns, requiring careful handling in industrial applications.
What are the physicochemical properties of 1,2,4-trichlorobenzene?
1,2,4-trichlorobenzene is a colorless to pale yellow liquid at room temperature with a characteristic aromatic odor. It has limited solubility in water but dissolves readily in organic solvents such as alcohol, ether, and benzene. The compound exhibits stability under normal conditions but may decompose when heated, releasing toxic chlorinated compounds. Its chlorinated aromatic structure gives it enhanced chemical resistance compared to unsubstituted benzene derivatives.
What is 1,2,4-trichlorobenzene used for?
1,2,4-trichlorobenzene serves primarily as an industrial solvent and chemical intermediate in manufacturing processes. It is commonly used in the production of pesticides, dyes, and other chlorinated organic compounds. The substance also finds application as a process solvent in chemical synthesis and as a heat transfer medium in certain industrial operations. Its stability and solvent properties make it valuable in specialized chemical manufacturing applications.
How to handle 1,2,4-trichlorobenzene safely?
1,2,4-trichlorobenzene requires careful handling due to its Acute Tox. 4 and Skin Irrit. 2 classifications. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Ensure adequate ventilation to minimize inhalation exposure and use the substance only in well-ventilated areas or fume hoods. Avoid contact with eyes and skin, and wash hands thoroughly after handling.
How to store 1,2,4-trichlorobenzene properly?
1,2,4-trichlorobenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers in a designated chemical storage area with appropriate secondary containment to prevent environmental release. Store away from incompatible materials such as strong oxidizing agents and bases. Ensure storage areas are equipped with appropriate spill containment measures and emergency response equipment due to its environmental hazard classification.
What to do in case of contact with 1,2,4-trichlorobenzene?
In case of skin contact with 1,2,4-trichlorobenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. If swallowed, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms develop or persist after exposure.
How to dispose of 1,2,4-trichlorobenzene properly?
1,2,4-trichlorobenzene must be disposed of as hazardous waste through licensed waste management companies due to its environmental hazard classification (Aquatic Acute 1; Aquatic Chronic 1). Do not discharge to sewers, waterways, or soil. Contaminated containers and materials require proper hazardous waste disposal. Follow local and national environmental regulations for chlorinated organic waste disposal. Consult with certified waste disposal specialists to ensure compliance with all applicable waste management requirements.
How to transport 1,2,4-trichlorobenzene?
1,2,4-trichlorobenzene is classified as ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles require proper placarding and emergency response information. Drivers must hold valid dangerous goods training certificates. Ensure compliance with ADR regulations for loading, segregation, and route restrictions when transporting this toxic substance across European borders.
Is 1,2,4-trichlorobenzene subject to specific regulations?
1,2,4-trichlorobenzene is subject to REACH registration requirements and CLP classification regulations in Europe, displaying GHS07 and GHS09 pictograms with 'Warning' signal word. While not currently listed as an SVHC (Substance of Very High Concern), it requires compliance with chemical safety assessments and exposure scenarios. Users must follow occupational exposure limits and environmental discharge restrictions. Check national chemical inventories and workplace safety regulations for additional requirements in specific European countries.
Where to buy 1,2,4-trichlorobenzene in Europe?
1,2,4-trichlorobenzene is available through OYSI, a specialized European distributor of technical chemicals and industrial solvents. OYSI provides quality-assured chemical products with proper documentation, safety data sheets, and regulatory compliance support across European markets. As a professional chemical supplier, OYSI ensures appropriate packaging, labeling, and delivery of hazardous substances like 1,2,4-trichlorobenzene to qualified industrial customers while maintaining strict safety and regulatory standards.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.