2,4,6-trichlorophenol
C6H3Cl3O
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Identification
- CAS Number
- 88-06-2
- EC Number
- 201-795-9
- UN Number
- 2020
- Index Number
- 604-018-00-5
- PubChem CID
- 6914
Physical-chemical properties
- Molecular Formula
- C6H3Cl3O
- Molar Mass
- 197.40 g/mol
- IUPAC Name
- 2,4,6-trichlorophenol
Chemical Identifiers
- InChI
- InChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
- InChI Key
- LINPIYWFGCPVIE-UHFFFAOYSA-N
Overview
2,4,6-trichlorophenol (CAS 88-06-2) is a chlorinated phenolic compound with antimicrobial properties and significant environmental persistence. This halogenated aromatic compound represents an important class of industrial chemicals characterized by three chlorine atoms substituted at positions 2, 4, and 6 on the phenol ring. With its molecular formula C6H3Cl3O and molecular weight of 197.4 g/mol, 2,4,6-trichlorophenol exhibits distinctive chemical properties that make it valuable for specific industrial applications while requiring careful handling due to its hazard profile. The compound is classified under multiple hazard categories including suspected carcinogenicity (Carc. 2), acute toxicity, skin and eye irritation, and significant aquatic toxicity. Its ADR classification as Class 6.1 reflects its toxic nature, necessitating appropriate safety measures during transport and handling. The GHS pictograms (GHS08, GHS07, GHS09) clearly indicate health hazards and environmental dangers associated with this substance. 2,4,6-trichlorophenol finds primary applications as an intermediate in the synthesis of pesticides and fungicides, where its biocidal properties are particularly valuable. It serves as a key building block in pharmaceutical manufacturing and acts as a preservative in certain industrial formulations. The compound is also utilized in the production of specialized polymers and resins. Unlike related compounds such as 4-aminophenol which is primarily used in pharmaceutical synthesis, 2,4,6-trichlorophenol's multiple chlorine substitutions provide enhanced antimicrobial efficacy. Due to its environmental persistence and bioaccumulation potential, this substance requires specialized handling expertise and proper waste management protocols. OYSI maintains reliable supply chains for 2,4,6-trichlorophenol to support European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Carc. 2; Acute Tox. 4 *; Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2020 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 2,4,6-Trichlorphenol, fest, frei von TCDD |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2,4,6-trichlorophenol?
2,4,6-trichlorophenol is an organochlorine compound with the molecular formula C6H3Cl3O and CAS number 88-06-2. It belongs to the chlorophenol family, characterized by three chlorine atoms attached to a phenol ring at positions 2, 4, and 6. With a molecular weight of 197.4 g/mol, this compound is classified as a potentially carcinogenic substance and poses significant environmental and health risks, requiring careful handling in industrial applications.
What are the physicochemical properties of 2,4,6-trichlorophenol?
2,4,6-trichlorophenol typically appears as white to pale yellow crystalline solid at room temperature with a characteristic phenolic odor. It has moderate solubility in water and is more soluble in organic solvents like alcohol and ether. The compound has a melting point around 69°C and exhibits volatility at elevated temperatures. Its chlorinated structure makes it relatively stable and resistant to biodegradation, contributing to its persistence in environmental systems.
What is 2,4,6-trichlorophenol used for?
2,4,6-trichlorophenol is primarily used as an intermediate in the synthesis of pesticides, herbicides, and fungicides. It serves as a precursor for manufacturing various agrochemicals and pharmaceutical compounds. The substance is also employed in wood preservation treatments and as a disinfectant in specific industrial applications. Due to its antimicrobial properties, it finds use in specialized cleaning formulations, though its applications are increasingly restricted due to environmental and health concerns.
How to handle 2,4,6-trichlorophenol safely?
Safe handling of 2,4,6-trichlorophenol requires comprehensive personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection when necessary. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin and eye contact, and prevent ingestion. Use appropriate engineering controls and ensure all personnel are trained in emergency procedures. Regular monitoring of workplace air quality is recommended due to the substance's toxic properties.
How to store 2,4,6-trichlorophenol correctly?
2,4,6-trichlorophenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep the substance separated from incompatible materials such as strong oxidizers and bases. Storage areas must be designed to prevent environmental release and equipped with appropriate containment measures. Maintain storage temperatures below 25°C when possible and ensure containers are properly labeled with hazard information and handling precautions.
What to do in case of contact with 2,4,6-trichlorophenol?
In case of skin contact with 2,4,6-trichlorophenol, immediately remove contaminated clothing and rinse affected areas with copious amounts of water for at least 15 minutes. For eye contact, flush eyes with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after exposure and provide safety data sheet information to medical personnel.
How to dispose of 2,4,6-trichlorophenol properly?
2,4,6-trichlorophenol must be disposed of as hazardous waste through licensed waste management facilities capable of handling toxic and potentially carcinogenic materials. Incineration at high temperatures in specialized facilities is typically required to ensure complete destruction. Never dispose of this substance in regular waste streams, sewers, or soil. Contact certified waste disposal companies and follow all local, national, and European regulations including the Waste Framework Directive for proper disposal documentation and tracking.
How to transport 2,4,6-trichlorophenol?
2,4,6-trichlorophenol is classified under ADR Class 6.1 (Toxic substances), Packing Group III, indicating moderate toxicity during transport. Shipments must use appropriate UN-specification packaging and display proper hazard labels and placards. Transport documentation must include emergency response information and proper shipping names. Vehicles should be equipped with appropriate spill response materials, and drivers must hold relevant dangerous goods certifications. Ensure compliance with ADR regulations for routing and vehicle requirements.
Is 2,4,6-trichlorophenol subject to specific regulations?
2,4,6-trichlorophenol is subject to comprehensive EU regulations including REACH registration requirements and CLP classification as Carcinogenic Category 2. The substance falls under various environmental protection directives due to its aquatic toxicity classification. It may be restricted or prohibited in certain consumer applications under REACH Annex XVII. Companies must comply with occupational exposure limits, environmental discharge restrictions, and proper hazard communication requirements throughout the supply chain.
Where to buy 2,4,6-trichlorophenol in Europe?
2,4,6-trichlorophenol is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substance supply. OYSI provides comprehensive regulatory support, proper packaging, and documentation compliance for industrial customers across Europe. As a professional chemical distributor, OYSI ensures product quality, regulatory compliance, and safe delivery while supporting customers with technical expertise and safety data sheets required for this controlled substance.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.