2,3,4,5-tetrachlorobenzoyl chloride

2,3,4,5-tetrachlorobenzoyl chloride is an organochlorine compound with the molecular formula C7HCl5O and CAS number 42221-52-3. This chemical belongs to the benzoyl chloride family, featuring four chlorine atoms attached to the benzene ring at positions 2, 3, 4, and 5, plus an additional chlorine in the acyl chloride functional group. With a molecular weight of 278.3 g/mol, it is classified as a corrosive substance with acute toxicity properties and skin sensitization potential.

2,3,4,5-tetrachlorobenzoyl chloride is typically a solid or liquid at room temperature, depending on purity and storage conditions. Like other benzoyl chlorides, it likely exhibits a pungent, acrid odor characteristic of acyl chlorides. The compound is highly reactive with water, undergoing hydrolysis to form the corresponding carboxylic acid and hydrochloric acid. It shows good solubility in organic solvents but reacts violently with protic solvents like water and alcohols.

2,3,4,5-tetrachlorobenzoyl chloride serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It functions as an acylating agent in the production of esters, amides, and other derivatives. The compound is valuable in the synthesis of chlorinated aromatic compounds, agrochemicals, and specialty pharmaceuticals. Its multiple chlorine substitutions make it particularly useful for creating highly chlorinated organic molecules with specific biological or chemical properties in research and industrial applications.

2,3,4,5-tetrachlorobenzoyl chloride requires careful handling due to its corrosive and toxic properties. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin, eyes, and clothing. Keep away from water and moisture to prevent violent reactions. Use appropriate tools and equipment resistant to corrosive chemicals, and ensure emergency eyewash and shower facilities are readily accessible.

2,3,4,5-tetrachlorobenzoyl chloride must be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from moisture and water sources. Keep containers away from incompatible materials such as alcohols, amines, and strong bases. Storage areas should be equipped with appropriate containment measures and maintained at stable temperatures. Ensure proper labeling according to GHS requirements and restrict access to authorized personnel only. Regular container inspection is essential to detect any signs of corrosion or leakage.

Immediate action is required upon contact with 2,3,4,5-tetrachlorobenzoyl chloride due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek urgent medical care. Always consult a physician after any exposure incident.

2,3,4,5-tetrachlorobenzoyl chloride disposal must comply with local and national hazardous waste regulations. The compound cannot be disposed of through regular waste streams due to its corrosive and toxic properties. Waste should be collected in appropriate containers, properly labeled, and handled by licensed hazardous waste disposal companies. Consider neutralization or treatment methods where applicable, but only under professional supervision. Always consult local environmental authorities for specific disposal requirements and approved treatment facilities.

2,3,4,5-tetrachlorobenzoyl chloride is classified as ADR Class 8 (corrosive substances), Packing Group II, indicating medium danger level. Transportation requires appropriate packaging that meets UN specifications for corrosive materials. Vehicles must display proper hazard placards and carry necessary documentation including safety data sheets. Drivers need ADR certification for dangerous goods transport. Packages must be properly labeled with GHS pictograms (GHS05, GHS07) and the 'Danger' signal word. Emergency response information must accompany shipments.

2,3,4,5-tetrachlorobenzoyl chloride falls under various European chemical regulations including REACH and CLP. While not classified as a SVHC (Substance of Very High Concern), it requires proper registration, classification, and labeling according to CLP regulation. The substance's acute toxicity, skin corrosion, and sensitization properties mandate specific safety measures and documentation. Companies handling this chemical must comply with occupational safety regulations and may need to implement risk management measures depending on use quantities and applications.

2,3,4,5-tetrachlorobenzoyl chloride is available through OYSI, a specialized European distributor of chemical products. OYSI provides this compound to pharmaceutical, research, and industrial customers across Europe, ensuring compliance with all relevant regulations including REACH and transport requirements. As a professional chemical distributor, OYSI offers proper documentation, safety data sheets, and technical support. Contact OYSI directly for availability, packaging options, and delivery arrangements to your specific European location, ensuring regulatory compliance throughout the supply chain.