1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol;hydrochloride

1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol;hydrochloride is an organofluorine compound with the molecular formula C8H8Cl2F3NO2 and CAS number 214353-17-0. This chemical features a trifluoroethane backbone attached to a chlorinated aromatic ring with an amino group. With a molecular weight of 278.05 g/mol, it is classified as a hazardous substance requiring careful handling due to its carcinogenic, toxic, and corrosive properties.

This compound exhibits properties typical of fluorinated organic molecules with its molecular formula C8H8Cl2F3NO2 and molecular weight of 278.05 g/mol. The presence of trifluoromethyl groups generally imparts chemical stability and lipophilicity. As a hydrochloride salt, it likely demonstrates enhanced water solubility compared to the free base form. The compound contains both polar (amino, hydroxyl) and non-polar (fluorinated) functional groups, affecting its solubility profile and physical characteristics.

This compound serves primarily as an intermediate in pharmaceutical synthesis and organic chemistry research. Fluorinated aromatic compounds like this are valuable building blocks in medicinal chemistry due to the unique properties imparted by fluorine atoms. The amino and diol functionalities provide reactive sites for further chemical modifications. Its specific structure suggests potential applications in developing pharmaceuticals or agrochemicals where fluorinated scaffolds are desired for enhanced biological activity or metabolic stability.

Safe handling requires comprehensive personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Skin Corr. 1B classification. Work must be conducted in a well-ventilated area or fume hood to prevent inhalation exposure (Acute Tox. 4). Given its Carc. 1B classification, minimize skin contact and implement strict hygiene protocols. Ensure emergency eyewash and shower facilities are readily accessible, and maintain proper ventilation systems to control airborne concentrations.

Proper storage requires a cool, dry, well-ventilated area away from incompatible materials and ignition sources. As a corrosive substance (ADR Class 8), store in appropriate chemical-resistant containers with secondary containment. Keep containers tightly sealed to prevent moisture absorption and contamination. Due to its carcinogenic classification, implement restricted access controls and maintain inventory tracking. Store separately from oxidizing agents, strong bases, and reactive metals to prevent dangerous reactions.

Immediate skin contact requires thorough washing with copious amounts of water for at least 15 minutes while removing contaminated clothing. For eye contact, flush immediately with water for 15-20 minutes and seek medical attention due to the corrosive nature. If inhaled, move to fresh air and monitor breathing. Due to the Carc. 1B and Acute Tox. 4 classifications, seek immediate medical attention for all exposure routes and provide the safety data sheet to medical personnel.

Disposal must comply with local, national, and EU hazardous waste regulations due to its carcinogenic and toxic properties. This compound requires treatment as hazardous waste and cannot be disposed of through normal waste streams. Engage licensed hazardous waste disposal companies for proper incineration or chemical treatment. Maintain detailed disposal records and ensure transportation follows ADR Class 8 requirements. Empty containers may also require special handling due to residual contamination.

Transportation follows ADR regulations for Class 8 corrosive substances, Packing Group II requirements. Packages must use appropriate UN-certified containers designed for corrosive materials with proper labeling including GHS pictograms (GHS08, GHS07, GHS05, GHS09). Transport vehicles require ADR certification and appropriate placarding. Documentation must include proper shipping names, hazard classifications, and emergency response information. Drivers need ADR training for Class 8 dangerous goods transportation.

This compound falls under EU REACH regulation requiring registration for manufacture or import above tonnage thresholds. CLP regulation mandates specific hazard classification and labeling (Carc. 1B; Acute Tox. 4; Skin Corr. 1B; Aquatic Chronic 2). While not currently listed as SVHC, its carcinogenic classification subjects it to strict workplace exposure controls and potential authorization requirements. National occupational health regulations may impose additional handling, storage, and exposure monitoring requirements for carcinogenic substances.

OYSI serves as a reliable European distributor for 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol;hydrochloride, providing comprehensive regulatory support and technical expertise. As specialized chemical distributors, OYSI ensures proper handling, documentation, and compliance with EU regulations including REACH and CLP requirements. Their European network enables efficient supply chain management while maintaining the strict safety standards required for this hazardous material. Contact OYSI directly for availability, specifications, and regulatory documentation.