2,3-dinitrophenol
C6H4N2O5
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Identification
- CAS Number
- 25550-58-7
- EC Number
- 247-096-2
- UN Number
- 0076
- Index Number
- 609-054-00-5
- PubChem CID
- 6191
Physical-chemical properties
- Molecular Formula
- C6H4N2O5
- Molar Mass
- 184.11 g/mol
- IUPAC Name
- 2,3-dinitrophenol
Chemical Identifiers
- InChI
- InChI=1S/C6H4N2O5/c9-5-3-1-2-4(7(10)11)6(5)8(12)13/h1-3,9H
- InChI Key
- MHKBMNACOMRIAW-UHFFFAOYSA-N
Overview
2,3-dinitrophenol (CAS 25550-58-7) is a nitrated phenolic compound with significant toxicological properties and specialized industrial applications. 2,3-dinitrophenol represents a specific isomer within the dinitrophenol family, characterized by nitro groups positioned at the 2 and 3 positions relative to the hydroxyl group on the benzene ring. This yellow crystalline solid with the molecular formula C6H4N2O5 exhibits distinct chemical behavior due to its unique substitution pattern, differentiating it from other nitrophenol derivatives and compounds such as 5-methyl-2-nitroaniline found in related chemical families. The compound's safety profile requires careful consideration, as evidenced by its classification under multiple acute toxicity categories and its designation as a substance causing specific target organ toxicity through repeated exposure. The presence of GHS06, GHS08, and GHS09 pictograms indicates acute toxicity, health hazards, and environmental risks respectively. Its ADR Class 1 classification necessitates specialized handling and transportation protocols due to explosive potential under certain conditions. The aquatic chronic toxicity classification underscores the importance of environmental protection measures during storage and use. Industrial applications of 2,3-dinitrophenol typically include its use as an intermediate in organic synthesis, particularly in the production of dyes and pigments where its nitro-substituted aromatic structure provides valuable reactivity. The compound also serves as a precursor in pharmaceutical synthesis and finds application in specialized analytical chemistry procedures. Like other nitroaromatic compounds including 3,5-dimethylaniline, it plays a role in the manufacture of various chemical intermediates requiring specific substitution patterns. OYSI maintains availability of 2,3-dinitrophenol for qualified industrial customers, ensuring compliance with all relevant safety and regulatory requirements throughout the European market.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 0076 |
| ADR Class | 1 |
| Packing Group | |
| Tunnel Code | B1000C |
| Proper Shipping Name | Dinitrophenol, trocken, nicht pulverförmig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2,3-dinitrophenol?
2,3-dinitrophenol is an organic chemical compound with the molecular formula C6H4N2O5 and CAS number 25550-58-7. This nitrophenol derivative contains two nitro groups attached to a phenol ring at positions 2 and 3. With a molecular weight of 184.11 g/mol, it belongs to the class of dinitrophenols, which are known for their high toxicity and potential explosive properties. The compound is classified as highly hazardous with multiple health and environmental warnings.
What are the physicochemical properties of 2,3-dinitrophenol?
2,3-dinitrophenol is typically a yellow to orange crystalline solid at room temperature. Like other dinitrophenols, it exhibits moderate solubility in water and good solubility in organic solvents such as alcohol and ether. The compound is sensitive to heat, shock, and friction due to its nitro groups, making it potentially explosive under certain conditions. It has a characteristic phenolic odor and can sublime at elevated temperatures.
What is 2,3-dinitrophenol used for?
2,3-dinitrophenol is primarily used as a chemical intermediate in organic synthesis and research applications. It serves as a precursor for manufacturing dyes, pharmaceuticals, and other organic compounds. In laboratory settings, it may be used for analytical purposes and chemical research. Due to its high toxicity and hazardous properties, its industrial applications are limited and strictly regulated. The compound requires specialized handling procedures and is typically used only by qualified professionals in controlled environments.
How to handle 2,3-dinitrophenol safely?
2,3-dinitrophenol must be handled with extreme caution due to its Acute Toxicity 3 classification and systemic toxicity effects. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid contact with skin, eyes, and inhalation of dust or vapors. Use non-sparking tools and avoid friction, impact, or heat sources that could trigger explosive decomposition.
How to store 2,3-dinitrophenol correctly?
2,3-dinitrophenol must be stored in a cool, dry place away from heat sources, direct sunlight, and incompatible materials. Keep containers tightly sealed and in original packaging. Store separately from strong bases, reducing agents, and combustible materials. The storage area should be well-ventilated and equipped with appropriate fire suppression systems. Due to its explosive potential, limit quantities stored and follow local regulations for explosive materials storage.
What to do in case of contact with 2,3-dinitrophenol?
Immediate action is required due to the compound's high acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician or poison control center after any exposure incident.
How to dispose of 2,3-dinitrophenol properly?
2,3-dinitrophenol disposal must comply with local and international hazardous waste regulations due to its toxicity and explosive properties. The compound cannot be disposed of in regular waste streams and requires specialized treatment by licensed hazardous waste contractors. Incineration at high temperatures in approved facilities is typically required. Small laboratory quantities may need neutralization before disposal. Always consult local environmental authorities and follow waste classification codes for proper disposal procedures.
How to transport 2,3-dinitrophenol?
2,3-dinitrophenol is classified under ADR Class 1 (explosives), requiring specialized packaging and transport procedures. Shipments must use approved explosive-rated containers with proper labeling including GHS06, GHS08, and GHS09 pictograms with 'Danger' signal word. Transport requires certified drivers and vehicles equipped for hazardous materials. Documentation must include proper shipping names, hazard classes, and emergency response information. Only authorized carriers experienced with explosive materials should handle transportation.
Is 2,3-dinitrophenol subject to specific regulations?
2,3-dinitrophenol is subject to extensive regulations under REACH, CLP, and explosive materials legislation. While not currently listed as an SVHC substance, its classification as Acute Tox. 3 and STOT RE 2 requires comprehensive safety data sheets and risk assessments. The compound falls under explosive materials regulations due to its ADR Class 1 classification. Import, handling, and use may require special permits and licenses depending on jurisdiction and quantities involved.
Where to buy 2,3-dinitrophenol in Europe?
2,3-dinitrophenol is available through specialized chemical distributors in Europe, including OYSI, which supplies high-quality laboratory and industrial chemicals. Due to the compound's hazardous classification and regulatory requirements, purchases typically require proper documentation, end-use declarations, and compliance verification. OYSI can provide technical support, safety data sheets, and regulatory guidance for European customers. Contact OYSI directly for availability, specifications, and regulatory compliance requirements for your specific application.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.