2,3-dinitrophenol

C6H4N2O5

CAS25550-58-7
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
25550-58-7
EC Number
247-096-2
UN Number
0076
Index Number
609-054-00-5
PubChem CID
6191

Physical-chemical properties

Molecular Formula
C6H4N2O5
Molar Mass
184.11 g/mol
IUPAC Name
2,3-dinitrophenol

Chemical Identifiers

InChI
InChI=1S/C6H4N2O5/c9-5-3-1-2-4(7(10)11)6(5)8(12)13/h1-3,9H
InChI Key
MHKBMNACOMRIAW-UHFFFAOYSA-N

Overview

2,3-dinitrophenol (CAS 66-56-8) is a dinitrophenol compound characterized by its explosive properties and phenolic structure. This aromatic nitro compound belongs to the dinitrophenol family, featuring two nitro groups positioned at the 2 and 3 positions on a phenol ring. With the molecular formula C6H4N2O5 and a molecular weight of 184.11 g/mol, 2,3-dinitrophenol exhibits distinctive chemical properties that make it valuable for specific industrial applications while requiring careful handling protocols. The compound's classification under ADR Class 1 indicates its explosive nature, which necessitates specialized storage, handling, and transportation procedures. This classification places it alongside other energetic materials that require strict adherence to safety regulations and proper risk management protocols. The presence of both nitro groups and the phenolic hydroxyl group contributes to its reactivity profile and potential applications. In industrial settings, 2,3-dinitrophenol finds primary use in the synthesis of specialized chemicals and as an intermediate in the production of dyes and pigments. Its explosive properties also make it relevant for certain pyrotechnic applications, though this requires extensive safety expertise and regulatory compliance. The compound shares structural similarities with related nitroaromatic compounds such as 2,4,6-trinitrobenzoic acid, which also features multiple nitro substitutions on aromatic rings. Due to its hazardous nature, proper handling requires appropriate personal protective equipment, controlled storage conditions, and compliance with local and international regulations governing explosive materials. Professional expertise in energetic materials is essential for safe utilization. OYSI provides 2,3-dinitrophenol to qualified industrial customers with the necessary technical documentation and safety guidance for compliant handling and application.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number0076
ADR Class1
Packing Group
Tunnel CodeB1000C
Proper Shipping NameDinitrophenol, trocken, nicht pulverförmig
Marine PollutantNo

Frequently Asked Questions

What is 2,3-dinitrophenol?

2,3-dinitrophenol is an organic chemical compound with the molecular formula C6H4N2O5 and CAS number 66-56-8. It belongs to the family of nitrophenols, characterized by the presence of two nitro groups (-NO2) attached to a phenol ring at positions 2 and 3. This aromatic compound has a molecular weight of 184.11 g/mol and exhibits distinctive chemical properties due to its nitro substituents and hydroxyl group combination.

What are the physicochemical properties of 2,3-dinitrophenol?

2,3-dinitrophenol appears as a yellow crystalline solid at room temperature with a melting point around 144-145°C. The compound is moderately soluble in water and more soluble in organic solvents like ethanol and acetone. It exhibits acidic properties due to the phenolic hydroxyl group, with the acidity enhanced by the electron-withdrawing nitro groups. The substance may decompose at high temperatures, potentially releasing toxic nitrogen oxides.

What is 2,3-dinitrophenol used for?

2,3-dinitrophenol is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. It serves in the production of dyes, pigments, and other aromatic compounds. The compound finds applications in pharmaceutical research and development, particularly in the synthesis of specialized organic molecules. It may also be used in analytical chemistry as a reagent for specific chemical reactions and in research laboratories for various synthetic pathways.

How to handle 2,3-dinitrophenol safely?

2,3-dinitrophenol should be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in a well-ventilated area or under a fume hood to avoid inhalation of dust or vapors. Avoid direct skin and eye contact, and prevent ingestion. Use non-sparking tools and equipment, as nitro compounds can be sensitive to friction and impact under certain conditions.

How to store 2,3-dinitrophenol correctly?

2,3-dinitrophenol should be stored in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Keep containers tightly closed and properly labeled. Store away from strong bases, reducing agents, and combustible materials. The storage area should be equipped with appropriate fire suppression systems and spill containment measures. Maintain storage temperatures below 25°C and ensure regular inspection of container integrity.

What to do in case of contact with 2,3-dinitrophenol?

In case of skin contact with 2,3-dinitrophenol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical advice if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 2,3-dinitrophenol appropriately?

2,3-dinitrophenol waste must be disposed of according to local and national hazardous waste regulations. The substance should be collected in appropriate containers and handed over to licensed waste disposal companies specializing in chemical waste treatment. Do not discharge into sewers, water bodies, or soil. Incineration at high temperatures in specialized facilities may be suitable, but must comply with environmental regulations and emission standards for nitrogen oxides.

How to transport 2,3-dinitrophenol?

2,3-dinitrophenol is classified under ADR Class 1, indicating it falls under explosive substances regulations for transport. Special packaging requirements and documentation must be followed according to dangerous goods transport regulations. Transport should be conducted by qualified personnel with appropriate training in handling explosive materials. Vehicles must display proper hazard placards, and specific routing restrictions may apply. Consult current ADR regulations for complete compliance requirements.

Is 2,3-dinitrophenol subject to specific regulations?

2,3-dinitrophenol is subject to various chemical regulations including REACH registration requirements in the European Union. The substance is not currently listed as a Substance of Very High Concern (SVHC), but manufacturers and importers must comply with CLP classification and labeling requirements. Users must ensure proper risk assessment and implement appropriate risk management measures. National regulations may impose additional restrictions on its use, storage, and handling.

Where to buy 2,3-dinitrophenol in Europe?

2,3-dinitrophenol is available through OYSI, a European distributor specializing in technical chemical products. As an established chemical supplier, OYSI can provide this compound to qualified industrial and research customers across Europe. Due to the specific nature and regulatory requirements of this substance, purchases typically require proper documentation and compliance with applicable regulations. Contact OYSI directly for availability, specifications, and ordering procedures.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.