2-methylaniline
C7H9N
Consulting for 2-methylaniline
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Identification
- CAS Number
- 95-53-4
- EC Number
- 202-429-0
- UN Number
- 1708
- Index Number
- 612-091-00-X
- PubChem CID
- 7242
Physical-chemical properties
- Molecular Formula
- C7H9N
- Molar Mass
- 107.15 g/mol
- IUPAC Name
- 2-methylaniline
Chemical Identifiers
- InChI
- InChI=1S/C7H9N/c1-6-4-2-3-5-7(6)8/h2-5H,8H2,1H3
- InChI Key
- RNVCVTLRINQCPJ-UHFFFAOYSA-N
Overview
2-methylaniline (CAS 95-53-4) is an aromatic amine compound with significant industrial applications and notable toxicological properties requiring careful handling protocols. This organic chemical, also known by its IUPAC designation 2-methylaniline, belongs to the substituted aniline family with the molecular formula C7H9N and a molecular weight of 107.15 g/mol. The compound features a benzene ring substituted with both an amino group and a methyl group in the ortho position, giving it distinct chemical reactivity compared to unsubstituted aniline or related compounds like N-methylaniline. From a safety perspective, 2-methylaniline presents several critical hazards that demand strict handling procedures. The substance is classified as a Category 1B carcinogen, indicating strong evidence of carcinogenic potential in humans. Additionally, it exhibits acute toxicity (Category 3) through multiple exposure routes and can cause eye irritation. The compound also poses environmental risks, particularly to aquatic ecosystems, as indicated by its Aquatic Acute 1 classification. These hazard properties are reflected in its ADR Class 6.1 designation for toxic substances and the requirement for GHS08, GHS06, and GHS09 pictograms with a "Danger" signal word. In industrial applications, 2-methylaniline serves primarily as an intermediate in organic synthesis, particularly in the production of dyes, pigments, and pharmaceutical compounds. The chemical industry utilizes this aromatic amine in manufacturing processes where its unique substitution pattern provides specific reactivity advantages. Additionally, it finds application in the synthesis of various specialty chemicals and as a building block for more complex molecular structures. OYSI maintains availability of 2-methylaniline for qualified industrial customers, ensuring proper regulatory compliance and technical support for safe handling and application requirements.
Safety & Classification
Carc. 1B; Acute Tox. 3 *; Acute Tox. 3 *; Eye Irrit. 2; Aquatic Acute 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1708 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | o-Toluidin, flüssig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-methylaniline?
2-methylaniline is an aromatic amine compound with the molecular formula C7H9N and CAS number 95-53-4. This organic chemical belongs to the aniline family, featuring a benzene ring with both an amino group (-NH2) and a methyl group (-CH3) attached. With a molecular weight of 107.15 g/mol, it is classified as a carcinogenic substance (Category 1B) and poses significant health and environmental hazards, requiring careful handling in industrial applications.
What are the physicochemical properties of 2-methylaniline?
2-methylaniline is typically a liquid at room temperature with a characteristic aniline-like odor. As an aromatic amine, it exhibits moderate solubility in water and good solubility in organic solvents like ethanol and ether. The compound tends to darken upon exposure to air and light due to oxidation. Its molecular structure, combining aromatic and amino functionalities, influences its reactivity and makes it useful as an intermediate in various chemical syntheses.
What is 2-methylaniline used for?
2-methylaniline serves primarily as a chemical intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It is commonly used in the production of azo dyes and various organic colorants for textile and printing industries. The compound also finds applications in the manufacture of antioxidants, rubber chemicals, and certain pharmaceutical intermediates. Due to its carcinogenic classification, its use is strictly regulated and limited to industrial processes with appropriate safety controls.
How to handle 2-methylaniline safely?
2-methylaniline requires strict safety protocols due to its carcinogenic and toxic properties. Personnel must wear full personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Skin and eye contact must be avoided at all costs. Emergency shower and eyewash stations should be readily accessible, and only trained personnel should handle this substance.
How to store 2-methylaniline correctly?
2-methylaniline must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. The storage area should be equipped with appropriate containment measures to prevent environmental release. Keep away from strong oxidizing agents and acids to prevent dangerous reactions. Containers should be clearly labeled with hazard warnings, and access should be restricted to authorized personnel only. Regular inspection of containers is recommended to detect any leaks or deterioration.
What to do in case of contact with 2-methylaniline?
Immediate action is crucial for any contact with 2-methylaniline. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure, regardless of severity.
How to dispose of 2-methylaniline properly?
2-methylaniline disposal must comply with local and national hazardous waste regulations due to its carcinogenic properties. The substance cannot be disposed of through regular waste streams and requires treatment by licensed hazardous waste disposal companies. Incineration at high temperatures in specialized facilities is typically the preferred method. Small quantities may require solidification or other pre-treatment before disposal. Always consult local environmental authorities for specific disposal requirements and approved disposal facilities.
How to transport 2-methylaniline?
2-methylaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group II, requiring specific transport protocols. Packages must bear appropriate hazard labels including GHS06, GHS08, and GHS09 pictograms with 'Danger' signal word. Transport vehicles must carry proper documentation and emergency response information. Drivers require ADR training for toxic substances. The substance must be transported in approved packaging that prevents leakage and is compatible with the chemical's properties.
Is 2-methylaniline subject to specific regulations?
2-methylaniline is subject to extensive regulatory oversight under multiple frameworks. Under CLP regulation, it's classified as Carcinogenic 1B, Acute Toxic 3, Eye Irritant 2, and Aquatic Acute 1. REACH registration requirements apply for manufacturers and importers. Many countries have occupational exposure limits and workplace restrictions due to its carcinogenic nature. Some jurisdictions may require special licenses for handling or using this substance. Users must comply with all applicable local, national, and international chemical safety regulations.
Where to buy 2-methylaniline in Europe?
2-methylaniline is available through OYSI, a European distributor specializing in technical chemical products. As a professional chemical supplier, OYSI ensures proper regulatory compliance and provides necessary safety documentation including Safety Data Sheets. Due to the substance's hazardous classification, purchases are typically restricted to qualified industrial users with appropriate handling capabilities. Contact OYSI directly for availability, specifications, and regulatory compliance documentation required for your specific application and location within Europe.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.