2-chloropropanoic acid
C3H5ClO2
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Identification
- CAS Number
- 598-78-7
- EC Number
- 209-952-3
- UN Number
- 2511
- Index Number
- 607-139-00-1
- PubChem CID
- 11734
Physical-chemical properties
- Molecular Formula
- C3H5ClO2
- Molar Mass
- 108.52 g/mol
- IUPAC Name
- 2-chloropropanoic acid
Chemical Identifiers
- InChI
- InChI=1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)
- InChI Key
- GAWAYYRQGQZKCR-UHFFFAOYSA-N
Overview
2-chloropropanoic acid (CAS 598-78-7) is an organochlorine carboxylic acid with corrosive properties and significant industrial applications. This halogenated organic compound, also known by its IUPAC designation 2-chloropropanoic acid, represents an important intermediate in chemical synthesis and manufacturing processes. With the molecular formula C3H5ClO2 and a molecular weight of 108.52 g/mol, this substance belongs to the alpha-halo acid family, characterized by the presence of a chlorine atom adjacent to the carboxyl group on the propanoic acid backbone. The compound exhibits strong corrosive properties, classified as Skin Corr. 1A under GHS regulations, requiring careful handling with appropriate personal protective equipment. Its acute toxicity classification (Acute Tox. 4) and ADR transport class 8 designation underscore the importance of proper storage and handling protocols. The associated GHS pictogrammes GHS05 and GHS07 with the signal word "Danger" clearly communicate the potential hazards to users. In industrial applications, 2-chloropropanoic acid serves primarily as a chemical intermediate in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. Its reactive chlorine substituent makes it valuable for nucleophilic substitution reactions and as a building block for more complex molecular structures. The compound also finds use in research and development applications where selective halogenation is required. Unlike stronger acids such as sulfurofluoridic acid, 2-chloropropanoic acid offers more controlled reactivity while maintaining sufficient activity for synthetic transformations. OYSI maintains reliable supply chains for this essential chemical intermediate, ensuring consistent availability for European industrial customers.
Safety & Classification
Acute Tox. 4 *; Skin Corr. 1A
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2511 |
| ADR Class | 8 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | alpha-Chlorpropionsäure, flüssig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-chloropropanoic acid?
2-chloropropanoic acid is an organochlorine compound with the molecular formula C3H5ClO2 and CAS number 598-78-7. This halogenated carboxylic acid has a molecular weight of 108.52 g/mol and features a chlorine atom attached to the second carbon of the propanoic acid chain. It is classified as a corrosive substance with acute toxicity properties, requiring careful handling due to its hazardous nature.
What are the physicochemical properties of 2-chloropropanoic acid?
2-chloropropanoic acid is typically a colorless to pale yellow liquid at room temperature with a pungent, acidic odor. The compound is highly soluble in water and polar organic solvents due to its carboxylic acid functional group. It exhibits typical carboxylic acid properties including acidic behavior in aqueous solutions and the ability to form salts with bases and esters with alcohols.
What is 2-chloropropanoic acid used for?
2-chloropropanoic acid serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is used in the production of various chemicals including herbicides, pharmaceuticals, and specialty organic compounds. The compound acts as a building block for more complex molecules where the chlorine substituent provides specific reactivity patterns useful in synthetic chemistry applications.
How to handle 2-chloropropanoic acid safely?
2-chloropropanoic acid requires strict safety protocols due to its Skin Corr. 1A and Acute Tox. 4 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Always use appropriate handling tools and ensure emergency shower and eyewash stations are accessible.
How to store 2-chloropropanoic acid correctly?
2-chloropropanoic acid should be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep away from strong bases, metals, and oxidizing agents. Storage areas should have appropriate spill containment measures and be constructed of materials resistant to corrosive substances. Maintain temperatures within recommended ranges to prevent degradation.
What to do in case of contact with 2-chloropropanoic acid?
In case of skin contact with 2-chloropropanoic acid, immediately remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. For eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical care. Always consult emergency services for serious exposures.
How to dispose of 2-chloropropanoic acid properly?
2-chloropropanoic acid must be disposed of according to local and national hazardous waste regulations. The substance cannot be disposed of in regular waste streams due to its corrosive and toxic properties. Contact licensed hazardous waste disposal companies for proper treatment. Small quantities may require neutralization under controlled conditions before disposal, but this should only be performed by trained professionals following established protocols.
How to transport 2-chloropropanoic acid?
2-chloropropanoic acid is classified under ADR Class 8 (corrosive substances), Packing Group III. Transportation requires appropriate hazardous goods documentation, proper labeling with corrosive placards, and use of approved packaging materials. Vehicles must comply with ADR regulations for corrosive substances. Drivers require hazardous materials training certification, and emergency response information must accompany shipments throughout transport.
Is 2-chloropropanoic acid subject to specific regulations?
2-chloropropanoic acid is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance is not currently listed as an SVHC (Substance of Very High Concern). Users must comply with workplace exposure limits, proper labeling requirements showing GHS07 and GHS05 pictograms, and maintain safety data sheets. Industrial users may need additional permits depending on usage quantities and applications.
Where to buy 2-chloropropanoic acid in Europe?
2-chloropropanoic acid is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to industrial customers across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures product quality and handles all necessary transportation and regulatory requirements for safe delivery to qualified industrial users.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.