2-chloropropanoic acid
C3H5ClO2
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Identification
- CAS Number
- 598-78-7
- EC Number
- 209-952-3
- UN Number
- 2511
- Index Number
- 607-139-00-1
- PubChem CID
- 11734
Physical-chemical properties
- Molecular Formula
- C3H5ClO2
- Molar Mass
- 108.52 g/mol
- IUPAC Name
- 2-chloropropanoic acid
Chemical Identifiers
- InChI
- InChI=1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)
- InChI Key
- GAWAYYRQGQZKCR-UHFFFAOYSA-N
Overview
2-chloropropanoic acid (CAS 598-78-7) is an organochlorine carboxylic acid with corrosive properties and significant industrial utility. This halogenated organic compound, also known by its IUPAC designation 2-chloropropanoic acid, represents an important intermediate in organic synthesis and industrial chemical processes. With the molecular formula C3H5ClO2 and a molecular mass of 108.52 g/mol, this substance belongs to the family of alpha-halogenated carboxylic acids, characterized by the presence of both a chlorine atom and a carboxyl functional group on adjacent carbon atoms. The compound exhibits notable chemical reactivity due to its dual functional nature, combining the electrophilic character of the carbon-chlorine bond with the acidic properties of the carboxyl group. This unique structure makes it particularly valuable in nucleophilic substitution reactions and as a building block for more complex molecular architectures. From a safety perspective, 2-chloropropanoic acid is classified as Acute Tox. 4 and Skin Corr. 1A under the GHS system, requiring careful handling protocols and appropriate personal protective equipment. Industrial applications include its use as an intermediate in pharmaceutical synthesis, where it serves as a precursor for various bioactive compounds. The chemical industry also employs it in the production of specialty chemicals and as a synthetic building block for agrochemical formulations. Unlike stronger acids such as sulfurofluoridic acid, 2-chloropropanoic acid offers more controlled reactivity while maintaining sufficient chemical potency for synthetic applications. OYSI maintains reliable supplies of 2-chloropropanoic acid to support European industrial and research applications, ensuring consistent quality and regulatory compliance for our technical chemical distribution network.
Safety & Classification
Acute Tox. 4 *; Skin Corr. 1A
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2511 |
| ADR Class | 8 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | alpha-Chlorpropionsäure, flüssig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-chloropropanoic acid?
2-chloropropanoic acid is a halogenated carboxylic acid with the molecular formula C3H5ClO2 and CAS number 598-78-7. This organic compound features a chlorine atom attached to the second carbon of a three-carbon propanoic acid chain. With a molecular weight of 108.52 g/mol, it is classified as a corrosive substance and acute toxin category 4, requiring careful handling due to its hazardous properties.
What are the physicochemical properties of 2-chloropropanoic acid?
2-chloropropanoic acid is typically a colorless to pale yellow liquid at room temperature with a pungent, acidic odor. It is highly soluble in water and most organic solvents due to its carboxylic acid functionality and relatively small molecular size. The compound exhibits typical carboxylic acid behavior, being acidic in nature and capable of forming salts with bases and esters with alcohols under appropriate conditions.
What is 2-chloropropanoic acid used for?
2-chloropropanoic acid serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is used in the production of various chemicals, including herbicides, pharmaceuticals, and specialty organic compounds. The compound's reactive chlorine and carboxylic acid groups make it valuable for creating more complex molecules through substitution and coupling reactions in chemical manufacturing processes.
How to handle 2-chloropropanoic acid safely?
2-chloropropanoic acid requires strict safety precautions due to its corrosive and toxic nature. Always wear chemical-resistant gloves, safety goggles, and protective clothing when handling. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin and eye contact, as the substance can cause severe burns and tissue damage. Keep emergency eyewash stations and safety showers readily accessible during handling operations.
How to store 2-chloropropanoic acid correctly?
2-chloropropanoic acid should be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers away from incompatible materials such as strong bases, metals, and oxidizing agents. Store in secondary containment to prevent environmental contamination in case of leaks. Maintain storage temperatures below 25°C and ensure containers are properly labeled with hazard information.
What to do in case of contact with 2-chloropropanoic acid?
Immediate action is crucial for 2-chloropropanoic acid exposure due to its corrosive properties. For skin contact, immediately flush with large amounts of water for at least 15 minutes while removing contaminated clothing. For eye contact, rinse continuously with water for 15 minutes and seek immediate medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek emergency medical care immediately.
How to dispose of 2-chloropropanoic acid properly?
2-chloropropanoic acid disposal must comply with local and European waste regulations as a hazardous chemical waste. The substance cannot be disposed of in regular drains or landfills due to its corrosive and toxic properties. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be neutralized carefully under controlled conditions by trained personnel before disposal, following specific regulatory guidelines and safety protocols.
How to transport 2-chloropropanoic acid?
2-chloropropanoic acid is classified under ADR Class 8 (Corrosive substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers suitable for corrosive materials and properly labeled with appropriate hazard placards. Transport vehicles must carry emergency response information and appropriate spill control materials. Only authorized carriers with proper training and equipment should handle the transportation of this hazardous chemical.
Is 2-chloropropanoic acid subject to specific regulations?
2-chloropropanoic acid is subject to European REACH regulation and CLP classification requirements. It is classified as Acute Tox. 4 and Skin Corr. 1A under CLP, requiring specific labeling with GHS pictograms GHS05 and GHS07 and the signal word 'Danger'. The substance is not currently listed as an SVHC (Substance of Very High Concern) under REACH, but suppliers must comply with registration and safety data sheet requirements.
Where to buy 2-chloropropanoic acid in Europe?
2-chloropropanoic acid is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. OYSI provides this compound with full regulatory compliance, proper packaging, and complete documentation including safety data sheets. As an established chemical distributor, OYSI ensures reliable supply chains and professional handling of hazardous chemicals like 2-chloropropanoic acid for various industrial applications.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.