2-chloroethanol

C2H5ClO

CAS107-07-3
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
107-07-3
EC Number
203-459-7
UN Number
1135
Index Number
603-028-00-7
PubChem CID
34

Physical-chemical properties

Molecular Formula
C2H5ClO
Molar Mass
80.51 g/mol
IUPAC Name
2-chloroethanol

Chemical Identifiers

InChI
InChI=1S/C2H5ClO/c3-1-2-4/h4H,1-2H2
InChI Key
SZIFAVKTNFCBPC-UHFFFAOYSA-N

Overview

2-chloroethanol (CAS 107-07-3) is a chlorinated alcohol compound with high toxicity and industrial solvent properties. This chemical substance, also known by its IUPAC name 2-chloroethanol, represents a significant compound in industrial chemistry applications. With the molecular formula C2H5ClO and a molecular weight of 80.51 g/mol, this colorless liquid combines the functional properties of both an alcohol and an organochlorine compound. The presence of both hydroxyl and chlorine groups in its structure makes it a versatile intermediate for various chemical synthesis processes. 2-chloroethanol exhibits high toxicity levels, classified under multiple acute toxicity categories including Acute Tox. 1 and Acute Tox. 2, requiring strict safety protocols during handling and storage. The substance carries the GHS06 pictogram and "Danger" signal word, indicating its severe health hazards. Transport regulations classify it under ADR class 6.1, reflecting its toxic nature. Like other halogenated compounds such as ethyl 2-bromoacetate, proper containment and specialized handling equipment are essential for safe industrial use. Primary industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, production of pesticides and agrochemicals, and as a solvent in specialized chemical processes. The compound serves as a building block for manufacturing various organic compounds, particularly in the production of ethylene oxide derivatives and certain polymer additives. OYSI provides 2-chloroethanol to qualified industrial customers throughout Europe, ensuring compliance with all relevant safety regulations and transport requirements for this controlled chemical substance.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1135
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameEthylenchlorhydrin
Marine PollutantNo

Frequently Asked Questions

What is 2-chloroethanol?

2-chloroethanol is an organochlorine compound with the molecular formula C2H5ClO and CAS number 107-07-3. This chemical substance has a molecular weight of 80.51 g/mol and belongs to the class of chlorinated alcohols. It is classified as highly toxic with Acute Tox. 1 and Acute Tox. 2 hazard classes, requiring careful handling due to its dangerous nature. The compound carries the GHS06 pictogram indicating acute toxicity and requires the signal word 'Danger' on safety labels.

What are the physicochemical properties of 2-chloroethanol?

2-chloroethanol is a colorless liquid at room temperature with a slightly sweet, ether-like odor. It is highly soluble in water and most organic solvents due to its polar nature from both the hydroxyl and chlorine groups. The compound has a boiling point of approximately 128°C and a density higher than water. It is hygroscopic and can absorb moisture from air. The presence of both chlorine and hydroxyl functional groups gives it unique reactivity properties.

What is 2-chloroethanol used for?

2-chloroethanol serves primarily as a chemical intermediate in the synthesis of various organic compounds. It is used in the production of pharmaceuticals, pesticides, and specialty chemicals. The compound acts as a building block for manufacturing ethylene oxide derivatives and serves as a solvent in specific industrial processes. It may also be employed in research and development applications for organic synthesis. Due to its high toxicity, its use is restricted to professional industrial applications with appropriate safety measures.

How to handle 2-chloroethanol safely?

2-chloroethanol requires extreme caution during handling due to its Acute Tox. 1 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Work should be conducted in a fume hood when possible. Avoid skin contact, inhalation, and ingestion completely. Use only in designated areas with emergency equipment readily available. Personnel must be trained in chemical safety procedures and emergency response protocols before handling this highly toxic substance.

How to store 2-chloroethanol correctly?

2-chloroethanol must be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Use appropriate chemical storage cabinets designed for toxic substances. Keep containers tightly sealed to prevent vapor release and moisture absorption. Store away from incompatible materials such as strong oxidizers, acids, and bases. Ensure storage areas have appropriate safety equipment including emergency showers and eyewash stations. Regular container inspection is essential to detect any signs of deterioration or leakage.

What to do in case of contact with 2-chloroethanol?

Immediate medical attention is required for any contact with 2-chloroethanol due to its high toxicity. For skin contact, remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. In case of eye contact, rinse immediately with water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Always contact poison control and provide the safety data sheet to medical personnel.

How to dispose of 2-chloroethanol appropriately?

2-chloroethanol must be disposed of as hazardous waste through licensed waste management companies specializing in toxic chemical disposal. Never pour down drains, into soil, or regular waste streams due to environmental and health risks. Collect waste in appropriate containers labeled for hazardous materials. Follow local and national regulations for hazardous waste disposal, including proper documentation and tracking. Consult with waste management professionals to ensure compliance with environmental regulations and safe disposal practices.

How to transport 2-chloroethanol?

2-chloroethanol is classified under ADR Class 6.1 (toxic substances) with Packing Group I, indicating high danger level during transport. It requires specialized packaging meeting UN specification standards and must be transported by qualified carriers with appropriate permits. Vehicles must display proper hazard placards and carry emergency response information. Transport documentation must include proper shipping names and hazard classifications. Only trained personnel should handle loading and unloading operations with appropriate safety equipment readily available.

Is 2-chloroethanol subject to specific regulations?

2-chloroethanol is subject to strict regulations under REACH and CLP in Europe due to its high toxicity classification. It requires registration for commercial use and must comply with classification, labeling, and packaging requirements showing GHS06 pictogram and 'Danger' signal word. The substance may be subject to authorization or restriction procedures under REACH. Companies must maintain safety data sheets and ensure proper worker training. Import and export may require additional permits depending on destination countries and quantities involved.

Where to buy 2-chloroethanol in Europe?

2-chloroethanol is available through specialized chemical distributors like OYSI, which supplies high-quality chemicals across Europe. Due to its toxic nature, purchase requires verification of legitimate industrial use and appropriate safety capabilities. Buyers must demonstrate proper storage facilities, trained personnel, and waste disposal arrangements. OYSI ensures compliance with all European regulations and provides complete documentation including safety data sheets. Contact OYSI's technical team for availability, specifications, and regulatory guidance for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.