2-chloroethanol

C2H5ClO

CAS107-07-3
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
107-07-3
EC Number
203-459-7
UN Number
1135
Index Number
603-028-00-7
PubChem CID
34

Physical-chemical properties

Molecular Formula
C2H5ClO
Molar Mass
80.51 g/mol
IUPAC Name
2-chloroethanol

Chemical Identifiers

InChI
InChI=1S/C2H5ClO/c3-1-2-4/h4H,1-2H2
InChI Key
SZIFAVKTNFCBPC-UHFFFAOYSA-N

Overview

2-chloroethanol (CAS 107-07-3) is a chlorinated alcohol compound with intermediate chemical properties and significant industrial applications. This halogenated organic compound, also known by its IUPAC name 2-chloroethanol, represents an important chemical intermediate in various industrial processes. With the molecular formula C2H5ClO and a molecular weight of 80.51 g/mol, this colorless liquid combines the reactive characteristics of both an alcohol functional group and a chlorine substituent, making it particularly valuable for synthetic chemistry applications. The presence of both hydroxyl and chloro groups in 2-chloroethanol creates a versatile molecule that can undergo diverse chemical transformations. However, this compound requires careful handling due to its classification under Acute Toxicity categories, with GHS06 pictogram indicating its dangerous nature. The substance falls under ADR class 6.1, emphasizing the need for appropriate safety protocols during transportation and storage. In industrial applications, 2-chloroethanol serves primarily as a chemical intermediate for manufacturing pharmaceuticals, agrochemicals, and specialty chemicals. Its bifunctional nature makes it useful in producing ethylene oxide derivatives and as a solvent in specific chemical processes. The compound shares certain reactive characteristics with related halogenated compounds such as ethyl 2-bromoacetate, though each maintains distinct applications based on their specific molecular structures. The chemical industry also utilizes 2-chloroethanol in the synthesis of surfactants and as a precursor for various organic compounds. Its dual functionality allows for selective chemical modifications, making it valuable in complex synthetic pathways where both alcohol and halide reactivity are required. OYSI maintains reliable supply chains for 2-chloroethanol, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1135
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameEthylenchlorhydrin
Marine PollutantNo

Frequently Asked Questions

What is 2-chloroethanol?

2-chloroethanol is an organochlorine compound with the molecular formula C2H5ClO and CAS number 107-07-3. This chemical substance has a molecular weight of 80.51 g/mol and belongs to the class of chlorinated alcohols. It is classified as highly toxic with acute toxicity categories 1 and 2, requiring careful handling due to its dangerous nature. The compound displays the GHS06 pictogram indicating its toxic properties.

What are the physicochemical properties of 2-chloroethanol?

2-chloroethanol is a colorless liquid at room temperature with a characteristic odor. It is highly soluble in water and most organic solvents due to its polar hydroxyl group combined with the chloroethyl structure. The compound has a boiling point around 128-130°C and demonstrates good miscibility with alcohols and ethers. Its density is approximately 1.2 g/cm³, making it denser than water.

What is 2-chloroethanol used for?

2-chloroethanol serves as an important chemical intermediate in various industrial applications. It is primarily used in the synthesis of pharmaceuticals, pesticides, and other organic compounds. The substance acts as a building block for producing ethylene oxide derivatives and serves as a solvent in certain chemical processes. Additionally, it finds application in the manufacture of dyes, surfactants, and specialty chemicals requiring chlorinated alcohol functionality.

How to handle 2-chloroethanol safely?

2-chloroethanol requires extreme caution during handling due to its high toxicity classification. Personal protective equipment must include chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Avoid skin contact, inhalation, and ingestion completely. Work in controlled environments with proper ventilation systems and emergency shower facilities readily available. Only trained personnel should handle this substance following strict safety protocols.

How to store 2-chloroethanol correctly?

2-chloroethanol must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers in secondary containment systems to prevent spills. Store separately from incompatible materials such as strong bases, oxidizing agents, and reactive metals. Maintain storage temperatures below 25°C and ensure proper labeling with hazard warnings. Access should be restricted to authorized personnel only.

What to do in case of contact with 2-chloroethanol?

Immediate action is critical due to 2-chloroethanol's high toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. In case of eye contact, flush with water for 15 minutes and remove contact lenses if present. For ingestion, do not induce vomiting and seek immediate medical care.

How to dispose of 2-chloroethanol appropriately?

2-chloroethanol disposal must comply with local and international hazardous waste regulations due to its toxic classification. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Contact licensed waste disposal companies for proper collection and treatment. Small quantities may require incineration at high temperatures with appropriate emission controls. Always consult local environmental authorities for specific disposal requirements.

How to transport 2-chloroethanol?

2-chloroethanol is classified under ADR class 6.1 (toxic substances) with packing group I, indicating maximum danger level. Transportation requires proper UN specification packaging, hazard labels, and documentation compliant with dangerous goods regulations. Vehicles must carry appropriate emergency equipment and drivers need ADR certification. The substance must be secured against movement and protected from temperature extremes during transit. Emergency response information must accompany shipments.

Is 2-chloroethanol subject to special regulations?

2-chloroethanol is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance's high toxicity classification triggers strict labeling, safety data sheet, and notification requirements. It may be subject to workplace exposure limits and special authorization procedures for certain uses. Users must comply with chemical safety assessments and risk management measures as specified by regulatory authorities.

Where to buy 2-chloroethanol in Europe?

2-chloroethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial and professional customers across Europe. As a regulated toxic substance, purchases require proper documentation, end-use declarations, and compliance with chemical regulations. OYSI provides technical support, safety documentation, and ensures regulatory compliance for professional applications. Contact OYSI directly for availability, specifications, and purchasing requirements in your region.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.