[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is a tropane alkaloid derivative commonly known as scopolamine or hyoscine. This compound has the molecular formula C17H21NO4 with a molar mass of 303.35 g/mol and CAS number 51-34-3. It features a complex tricyclic structure with both nitrogen and oxygen heteroatoms, making it a highly bioactive pharmaceutical compound with significant therapeutic applications.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is typically a white to off-white crystalline powder at room temperature. It has a molecular weight of 303.35 g/mol and is moderately soluble in water and organic solvents like ethanol and chloroform. The compound is generally odorless and stable under normal storage conditions, though it should be protected from light and moisture to maintain its integrity.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is primarily used in pharmaceutical manufacturing as an active ingredient in medications for motion sickness, postoperative nausea, and as a preoperative sedative. It is also utilized in research applications for studying cholinergic systems and neurological processes. Industrial applications include its use as an intermediate in the synthesis of related pharmaceutical compounds and in analytical chemistry as a reference standard.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate requires extreme caution due to its Acute Toxicity 1 and 2 classifications. Essential PPE includes nitrile gloves, safety goggles, lab coat, and respiratory protection when handling powders. Work in a well-ventilated area or fume hood, avoid skin and eye contact, and never ingest. Wash hands thoroughly after handling and ensure emergency shower and eyewash stations are accessible.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate must be stored in a locked, secure area due to its high toxicity classification. Keep in original containers in a cool, dry place away from direct light and heat sources. Maintain temperatures between 2-8°C when possible. Store separately from food, beverages, and incompatible materials. Ensure proper labeling and restrict access to authorized personnel only.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate exposure requires immediate medical attention due to its extreme toxicity. For skin contact, remove contaminated clothing and flush with water for 15 minutes. For eye contact, rinse continuously with water and seek immediate medical care. If inhaled, move to fresh air and monitor breathing. Never induce vomiting if ingested. Contact emergency services immediately and provide the safety data sheet to medical personnel.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate waste must be disposed of through licensed hazardous waste contractors due to its high toxicity classification. Never dispose of in regular waste streams or pour down drains. Collect waste in appropriate containers, label clearly, and maintain disposal records. Follow local and national regulations for hazardous pharmaceutical waste. Small quantities may require incineration at authorized facilities under controlled conditions.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is classified as ADR Class 6.1, Packing Group I, indicating it is a highly toxic substance requiring special transport procedures. Use UN-approved packaging with proper hazard labels and documentation. Transport vehicles must carry appropriate emergency equipment and drivers need ADR training. Shipments require dangerous goods declarations and must follow specific routing restrictions to minimize public exposure risks.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is subject to strict pharmaceutical regulations and controlled substance laws in many jurisdictions due to its psychoactive properties. It falls under REACH registration requirements for chemical substances in Europe and CLP classification for hazard communication. The compound is not currently listed as an SVHC substance but may be subject to additional restrictions for import/export and requires proper licensing for handling and distribution.

[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is available through OYSI, a trusted European distributor of specialty chemicals and pharmaceutical intermediates. As a regulated substance, purchase requires proper documentation, licenses, and end-use declarations. OYSI ensures compliance with all relevant European regulations and provides certified products with appropriate safety documentation. Contact OYSI directly for availability, technical specifications, and regulatory guidance for your specific application requirements.