Ethylene oxide
C2H4O
ethylene oxide
Consulting for Ethylene oxide
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Identification
- CAS Number
- 75-21-8
- EC Number
- 200-849-9
- UN Number
- 1040
- Index Number
- 603-001-00-X
- PubChem CID
- 6354
Physical-chemical properties
- Molecular Formula
- C2H4O
- Molar Mass
- 44.05 g/mol
- IUPAC Name
- ethylene oxide
Chemical Identifiers
- InChI
- InChI=1S/C2H4O/c1-2-3-1/h1-2H2
- InChI Key
- IAYPIBMASNFSPL-UHFFFAOYSA-N
Overview
Ethylene oxide (CAS 75-21-8) is a highly reactive cyclic ether with significant industrial importance as a sterilizing agent and chemical intermediate. This colorless gas at room temperature represents one of the most versatile building blocks in the chemical industry, despite its hazardous nature. With the molecular formula C2H4O and a molecular weight of 44.05 g/mol, ethylene oxide features a three-membered ring structure that makes it exceptionally reactive due to ring strain. This reactivity, while valuable for industrial processes, also contributes to its classification as a flammable gas, carcinogen, mutagen, and reproductive toxicant under the GHS system. The substance exists as a pressurized gas under normal conditions and requires careful handling due to its multiple hazard classifications. Its high reactivity makes it prone to polymerization and explosive decomposition, necessitating specialized storage and transportation protocols under ADR Class 2 regulations. Unlike less reactive gases such as carbon monoxide, ethylene oxide's ring structure enables it to participate in ring-opening reactions that form the basis of many industrial applications. Primary industrial applications include the sterilization of medical devices and pharmaceutical products, where its penetrating properties and broad-spectrum antimicrobial activity make it invaluable for heat-sensitive materials. The chemical industry utilizes ethylene oxide extensively as an intermediate in producing ethylene glycol, surfactants, and glycol ethers. Additionally, it serves as a key component in manufacturing polyethylene oxide polymers and various specialty chemicals. OYSI provides ethylene oxide to qualified industrial customers with comprehensive safety documentation and technical support for proper handling procedures.
Safety & Classification
Flam. Gas 1; Press. Gas; Carc. 1B; Muta. 1B; Repr. 1B; Acute Tox. 3; Acute Tox. 3; STOT SE 3; STO...
GHS Pictograms
Flame
GHS02
Flammable. May ignite on contact with air, water, or heat sources.
Gas Cylinder
GHS04
Gases under pressure. May explode if heated.
Health Hazard
GHS08
Serious health hazard. May cause cancer, organ damage, or genetic defects.
Skull and Crossbones
GHS06
Acute toxicity. Fatal if swallowed, in contact with skin, or if inhaled.
Corrosion
GHS05
Corrosive. Causes severe skin burns and eye damage.
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Extremely flammable gas.
May cause cancer.
May cause genetic defects.
Toxic if inhaled.
Toxic if swallowed.
May cause respiratory irritation.
May cause drowsiness or dizziness.
Causes damage to organs through prolonged or repeated exposure.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1040 |
| ADR Class | 2 |
| Tunnel Code | B/D |
| Proper Shipping Name | Ethylenoxid, unter Druck verflüssigt |
| Marine Pollutant | No |
Frequently Asked Questions
What is ethylene oxide?
Ethylene oxide is a highly reactive organic compound with the molecular formula C2H4O and CAS number 75-21-8. This colorless gas with a sweet, ether-like odor is one of the most important industrial chemicals, serving as a key intermediate in chemical manufacturing. With a molecular weight of 44.05 g/mol, ethylene oxide is classified as extremely hazardous due to its flammable, carcinogenic, mutagenic, and reproductive toxicity properties.
What are the physicochemical properties of ethylene oxide?
Ethylene oxide is a colorless gas at room temperature with a characteristic sweet, ether-like odor. It has a molecular weight of 44.05 g/mol and exists as a pressurized gas under normal storage conditions. The compound is highly reactive due to its three-membered ring structure, making it extremely flammable and prone to explosive polymerization. It is completely miscible with water and most organic solvents.
What is ethylene oxide used for?
Ethylene oxide serves primarily as a chemical intermediate in the production of ethylene glycol, which is used in antifreeze and polyester manufacturing. It is also widely used as a sterilizing agent for medical equipment and pharmaceutical products due to its ability to penetrate packaging materials. Additionally, ethylene oxide is employed in the production of surfactants, detergents, and various specialty chemicals in industrial applications.
How to handle ethylene oxide safely?
Ethylene oxide requires extreme safety precautions due to its multiple hazard classifications including carcinogenicity, mutagenicity, and acute toxicity. Personnel must use appropriate respiratory protection, gas-tight chemical protective clothing, and work in well-ventilated areas or under fume extraction. All ignition sources must be eliminated, and specialized gas detection equipment should be used. Only trained personnel should handle this substance following strict safety protocols.
How to store ethylene oxide correctly?
Ethylene oxide must be stored in pressurized containers designed for hazardous gases, kept in cool, well-ventilated areas away from heat, sparks, and ignition sources. Storage areas should be equipped with gas detection systems and emergency ventilation. The substance should be segregated from incompatible materials including acids, bases, and oxidizing agents. Temperature control is critical to prevent dangerous pressure buildup and potential explosive decomposition.
What to do in case of contact with ethylene oxide?
Ethylene oxide exposure requires immediate emergency response due to its acute toxicity. In case of inhalation, move the person to fresh air immediately and seek medical attention. For skin contact, remove contaminated clothing and flush with plenty of water. Eye contact requires immediate irrigation with clean water for at least 15 minutes. All exposures should be treated as medical emergencies requiring professional healthcare evaluation.
How to dispose of ethylene oxide properly?
Ethylene oxide disposal must comply with hazardous waste regulations due to its classification as carcinogenic, mutagenic, and acutely toxic. The substance should never be released to the environment and requires specialized treatment at authorized hazardous waste facilities. Disposal methods typically involve controlled incineration or chemical neutralization by qualified waste management companies. All disposal activities must follow local and EU waste management regulations.
How to transport ethylene oxide?
Ethylene oxide is classified under ADR Class 2 (gases) for transportation, requiring specialized packaging and handling procedures for hazardous gases. Transport must be conducted by certified carriers using appropriate gas cylinders or containers designed for pressurized hazardous materials. Vehicles must be equipped with proper placarding, emergency equipment, and documentation. Drivers require special training for transporting dangerous goods.
Is ethylene oxide subject to specific regulations?
Ethylene oxide is heavily regulated under multiple EU frameworks including CLP regulation with Danger signal word and multiple hazard classifications (carcinogenic 1B, mutagenic 1B, reproductive toxicity 1B). It requires REACH registration for commercial use and is subject to workplace exposure limits due to its severe health hazards. Special authorization may be required for certain applications, and strict occupational safety measures must be implemented.
Where to buy ethylene oxide in Europe?
Ethylene oxide is available through OYSI, a European distributor of technical chemicals, subject to regulatory compliance and safety requirements. Due to its hazardous classification and regulatory restrictions, procurement requires proper business justification, safety infrastructure, and trained personnel. Buyers must demonstrate appropriate handling capabilities and regulatory compliance before purchase authorization. Contact OYSI for specific availability and regulatory requirements in your region.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.