1,4-dichlorobut-2-ene

C4H6Cl2

CAS764-41-0
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
764-41-0
EC Number
212-121-8
UN Number
2927
Index Number
602-073-00-X
PubChem CID
15122

Physical-chemical properties

Molecular Formula
C4H6Cl2
Molar Mass
124.99 g/mol
IUPAC Name
1,4-dichlorobut-2-ene

Chemical Identifiers

InChI
InChI=1S/C4H6Cl2/c5-3-1-2-4-6/h1-2H,3-4H2
InChI Key
FQDIANVAWVHZIR-UHFFFAOYSA-N

Overview

1,4-Dichlorobut-2-ene (CAS 764-41-0) is an organochlorine compound with significant chemical reactivity and high toxicity hazard classification. This chlorinated alkene represents an important intermediate in organic synthesis and industrial chemistry applications. The compound features a four-carbon chain with chlorine atoms positioned at the terminal carbons and a double bond between carbons 2 and 3, giving it unique reactivity characteristics. With the molecular formula C4H6Cl2 and a molecular weight of 124.99 g/mol, 1,4-dichlorobut-2-ene exhibits properties typical of halogenated alkenes while presenting significant safety considerations due to its classification profile. The substance carries multiple hazard classifications including Category 1B carcinogenicity, acute toxicity ratings, and skin corrosion properties, requiring stringent handling protocols and specialized safety equipment. Its GHS pictograms (GHS08, GHS06, GHS05, GHS09) reflect the serious health hazards, acute toxicity, corrosive nature, and environmental risks associated with this compound. The ADR Class 6.1 designation further emphasizes its toxic properties for transportation purposes. In industrial applications, 1,4-dichlorobut-2-ene serves primarily as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals, where its reactive chlorine substituents enable further chemical transformations. It also finds use in polymer chemistry applications and as a building block for more complex organic molecules. While structurally different from related compounds like 2-chloroacetaldehyde, it shares similar reactivity patterns with other chlorinated organic intermediates. OYSI provides 1,4-dichlorobut-2-ene to qualified industrial customers with comprehensive safety documentation and regulatory compliance support for specialized chemical synthesis applications.

Safety & Classification

Danger
Classification:

Carc. 1B; Acute Tox. 2 *; Acute Tox. 3 *; Acute Tox. 3 *; Skin Corr. 1B; Aquatic Acute 1; Aquatic...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H330

Fatal if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H314

Causes severe skin burns and eye damage.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2927
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1,4-Dichlorbut-2-en, cis/trans-Isomere oder Isomerengemisch
Marine PollutantNo

Frequently Asked Questions

What is 1,4-dichlorobut-2-ene?

1,4-dichlorobut-2-ene is an organochlorine compound with the molecular formula C4H6Cl2 and CAS number 764-41-0. This chemical substance has a molecular weight of 124.99 g/mol and contains a double bond between carbon atoms 2 and 3, with chlorine atoms attached to positions 1 and 4. It is classified as a highly hazardous substance due to its carcinogenic properties and acute toxicity, requiring specialized handling and safety measures in industrial applications.

What are the physicochemical properties of 1,4-dichlorobut-2-ene?

1,4-dichlorobut-2-ene is a chlorinated organic compound that typically exists as a liquid at room temperature. Due to its chlorinated alkene structure, it exhibits limited water solubility but dissolves well in organic solvents. The presence of the C=C double bond and two chlorine substituents influences its reactivity and stability. The compound's physical properties are characteristic of small halogenated hydrocarbons, with specific gravity and boiling point values typical for molecules of this molecular weight and structure.

What is 1,4-dichlorobut-2-ene used for?

1,4-dichlorobut-2-ene serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It is used in specialized industrial processes where its unique structural properties - containing both a double bond and two chlorine atoms - make it valuable for creating more complex molecules. Due to its high toxicity and carcinogenic classification, its applications are limited to controlled industrial environments with appropriate safety measures and regulatory compliance.

How to handle 1,4-dichlorobut-2-ene safely?

1,4-dichlorobut-2-ene requires extreme caution during handling due to its Carc. 1B and Acute Tox. 2-3 classifications. Essential personal protective equipment includes chemical-resistant gloves, full face protection, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Skin and eye contact must be absolutely avoided due to its Skin Corr. 1B classification. Only trained personnel should handle this substance following strict safety protocols.

How to store 1,4-dichlorobut-2-ene correctly?

1,4-dichlorobut-2-ene must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage containers should be made of compatible materials resistant to corrosion. Due to its carcinogenic and highly toxic nature, it requires secure storage with restricted access and appropriate labeling with GHS pictograms (GHS08, GHS06, GHS05, GHS09). Temperature control and protection from light may be necessary to prevent degradation and maintain product stability.

What to do in case of contact with 1,4-dichlorobut-2-ene?

1,4-dichlorobut-2-ene contact requires immediate emergency response due to its corrosive and toxic nature. For skin contact, immediately remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water and seek urgent medical attention. If inhaled, move the person to fresh air immediately. For all exposure routes, seek immediate medical attention and provide the safety data sheet to medical personnel.

How to dispose of 1,4-dichlorobut-2-ene appropriately?

1,4-dichlorobut-2-ene disposal requires specialized hazardous waste management due to its carcinogenic and highly toxic classification. The substance cannot be disposed of through regular waste streams and must be handled by licensed hazardous waste contractors. Incineration at high temperatures in specialized facilities equipped with appropriate emission controls is typically required. All disposal activities must comply with local, national, and European waste regulations, including proper documentation and tracking throughout the disposal process.

How to transport 1,4-dichlorobut-2-ene?

1,4-dichlorobut-2-ene is classified under ADR Class 6.1 (toxic substances), Packing Group II, indicating high toxicity requiring special transport precautions. Transportation must comply with dangerous goods regulations, including appropriate packaging, labeling, and documentation. Vehicles must carry emergency response information and appropriate safety equipment. Only authorized carriers trained in hazardous materials transport should handle shipments. Proper shipping names, hazard labels, and emergency contact information must accompany all shipments.

Is 1,4-dichlorobut-2-ene subject to specific regulations?

1,4-dichlorobut-2-ene is subject to extensive European chemical regulations under REACH and CLP due to its carcinogenic classification and high toxicity. Its Carc. 1B status may trigger authorization requirements or restrictions under REACH Annex XIV or XVII. Users must comply with occupational exposure limits, workplace safety regulations, and environmental protection measures. The substance requires proper classification, labeling, and safety data sheet communication throughout the supply chain, with potential notification requirements for certain uses.

Where to buy 1,4-dichlorobut-2-ene in Europe?

1,4-dichlorobut-2-ene is available through specialized chemical distributors in Europe, including OYSI, which supplies high-quality chemical products to industrial customers. Due to its hazardous classification and regulatory requirements, procurement requires proper authorization, safety documentation, and compliance verification. Suppliers must ensure appropriate packaging, labeling, and transportation arrangements. Contact OYSI's technical team for availability, regulatory support, and safe supply chain management for this controlled substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.