2-(2,4,5-trichlorophenoxy)acetic acid

C8H5Cl3O3

CAS93-76-5
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
93-76-5
EC Number
202-273-3
UN Number
3077
Index Number
607-041-00-9
PubChem CID
1480

Physical-chemical properties

Molecular Formula
C8H5Cl3O3
Molar Mass
255.50 g/mol
IUPAC Name
2-(2,4,5-trichlorophenoxy)acetic acid

Chemical Identifiers

InChI
InChI=1S/C8H5Cl3O3/c9-4-1-6(11)7(2-5(4)10)14-3-8(12)13/h1-2H,3H2,(H,12,13)
InChI Key
SMYMJHWAQXWPDB-UHFFFAOYSA-N

Overview

2-(2,4,5-trichlorophenoxy)acetic acid (CAS 93-76-5) is an organochlorine compound with herbicidal properties and significant regulatory restrictions due to environmental persistence. This chlorinated phenoxyacetic acid derivative, commonly known as 2,4,5-T, represents a class of synthetic auxin herbicides that were historically significant in agricultural and forestry applications. The compound features a trichlorophenoxy group attached to an acetic acid moiety, resulting in a molecular formula of C8H5Cl3O3 and a molecular weight of 255.5 g/mol. Its chemical structure, similar to other organochlorine compounds like chloromercury derivatives, contributes to its environmental persistence and bioaccumulation potential. The substance exhibits moderate acute toxicity (Acute Tox. 4) and presents specific target organ toxicity following single exposure (STOT SE 3). Safety considerations include skin and eye irritation properties (Skin Irrit. 2, Eye Irrit. 2), requiring appropriate personal protective equipment during handling. Of particular concern are its aquatic toxicity characteristics, classified as both Aquatic Acute 1 and Aquatic Chronic 1, indicating severe immediate and long-term effects on aquatic organisms. The compound is classified under ADR Class 9 for transport purposes, reflecting its miscellaneous dangerous substance status. Industrial applications have been severely restricted in many jurisdictions due to environmental and health concerns. Historically, the compound found use in selective herbicide formulations for broadleaf weed control and brush clearing operations in forestry management. Research applications may involve studies on organochlorine environmental fate and remediation technologies. OYSI maintains technical-grade 2-(2,4,5-trichlorophenoxy)acetic acid availability for qualified industrial and research customers, ensuring full regulatory compliance and comprehensive safety documentation for all shipments.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2,4,5-T (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 2-(2,4,5-trichlorophenoxy)acetic acid?

2-(2,4,5-trichlorophenoxy)acetic acid is an organochlorine compound with the molecular formula C8H5Cl3O3 and CAS number 93-76-5. This synthetic chemical belongs to the phenoxyacetic acid family and has a molecular weight of 255.5 g/mol. It is classified as a hazardous substance with moderate toxicity, skin and eye irritation properties, and significant environmental concerns due to its aquatic toxicity.

What are the physicochemical properties of 2-(2,4,5-trichlorophenoxy)acetic acid?

2-(2,4,5-trichlorophenoxy)acetic acid is typically a white to off-white crystalline solid at room temperature. The compound has limited water solubility but dissolves readily in organic solvents such as alcohols and acetone. It exhibits good thermal stability under normal storage conditions and has a characteristic phenolic odor. The presence of three chlorine atoms contributes to its chemical stability and environmental persistence.

What is 2-(2,4,5-trichlorophenoxy)acetic acid used for?

2-(2,4,5-trichlorophenoxy)acetic acid is primarily used as an intermediate in the synthesis of herbicides and plant growth regulators. It serves as a key building block in pharmaceutical manufacturing and chemical research applications. The compound is also utilized in analytical chemistry as a reference standard and in specialized industrial processes requiring selective organic synthesis. Its applications are mainly restricted to professional and industrial use due to safety considerations.

How to handle 2-(2,4,5-trichlorophenoxy)acetic acid safely?

2-(2,4,5-trichlorophenoxy)acetic acid requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin and eye contact, and prevent dust generation during handling. Use non-sparking tools and ensure proper grounding of equipment. Always wash hands thoroughly after handling and before eating or drinking.

How to store 2-(2,4,5-trichlorophenoxy)acetic acid correctly?

2-(2,4,5-trichlorophenoxy)acetic acid should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and store separately from incompatible materials such as strong bases, oxidizing agents, and reactive metals. Use original containers or approved chemical storage vessels. Maintain storage temperatures below 25°C and ensure adequate containment measures to prevent environmental release in case of spillage.

What to do in case of contact with 2-(2,4,5-trichlorophenoxy)acetic acid?

Skin contact with 2-(2,4,5-trichlorophenoxy)acetic acid requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist or worsen.

How to dispose of 2-(2,4,5-trichlorophenoxy)acetic acid properly?

2-(2,4,5-trichlorophenoxy)acetic acid must be disposed of through licensed hazardous waste disposal facilities in accordance with local and national regulations. Never dispose of this substance in regular waste streams, sewers, or the environment due to its aquatic toxicity classification. Contact certified waste management companies for proper collection and treatment. Ensure proper documentation and waste tracking as required by applicable environmental legislation.

How to transport 2-(2,4,5-trichlorophenoxy)acetic acid?

2-(2,4,5-trichlorophenoxy)acetic acid is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. It requires appropriate UN-specification packaging and proper labeling with Class 9 hazard labels. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers need ADR certification for dangerous goods transport. Ensure compliance with quantity limitations and routing restrictions as specified in ADR regulations.

Is 2-(2,4,5-trichlorophenoxy)acetic acid subject to specific regulations?

2-(2,4,5-trichlorophenoxy)acetic acid is subject to REACH registration requirements in Europe and must comply with CLP classification and labeling regulations. While not currently listed as an SVHC substance, it requires safety data sheets and proper hazard communication due to its toxicity and environmental impact classifications. Users must implement appropriate risk management measures and may need to comply with industrial emissions directives and water framework regulations.

Where to buy 2-(2,4,5-trichlorophenoxy)acetic acid in Europe?

2-(2,4,5-trichlorophenoxy)acetic acid is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with full regulatory compliance including safety data sheets, certificates of analysis, and proper packaging for industrial and research applications. As a professional chemical distributor, OYSI ensures quality standards and regulatory compliance for customers across European markets requiring this specialized chemical intermediate.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.